Docking and scoring for nucleic acid–ligand interactions: principles and current status

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Yuyu Feng ◽  
Yumeng Yan ◽  
Jiahua He ◽  
Huanyu Tao ◽  
Qilong Wu ◽  
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Sequence-programmed self-assembly provides multivalent nucleic acid–ligand constructs used as tailor-made probes for unravelling and exploiting the mechanisms of multivalency-enhanced interactions on protein receptors.


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Vol 51 (23) ◽  
pp. 4906-4909 ◽  
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Daria V. Berdnikova ◽  
Tseimur M. Aliyeu ◽  
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Controlled DNA binding: a photoresponsive ligand is made to migrate from cyclodextrin to double-stranded DNA upon irradiation and is eventually extracted from the nucleic acid by cucurbituril.


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