This chapter compares two quantitative frameworks, namely, Computable General Equilibrium (CGE) and Econometric models to study the impacts of climate change on human economy. However, as is inferred from this chapter, CGE framework is fraught with unrealistic assumptions, and fails to capture impacts of climate change and extreme events on the ecosystem services. On the other hand, econometric framework can be customised and is not based on the unrealistic assumptions like CGE. The various advantages and disadvantages of the two methods have been discussed critically in the process in this chapter in light of the avowed objective of understanding sustainability science.