scholarly journals StarD13 negatively regulates invadopodia formation and invasion in high-grade serous (HGS) ovarian adenocarcinoma cells by inhibiting Cdc42

2021 ◽  
pp. 151197
Author(s):  
Sandra Abdellatef ◽  
Isabelle Fakhoury ◽  
Maria Al Haddad ◽  
Leila Jaafar ◽  
Hiba Maalouf ◽  
...  
Keyword(s):  
High Grade ◽  
Ovarian Adenocarcinoma ◽  
Adenocarcinoma Cells ◽  
Invadopodia Formation

scholarly journals CD437 induces apoptosis in ovarian adenocarcinoma cells via ER stress signaling

2008 ◽  
Vol 366 (3) ◽  
pp. 840-847 ◽  
Author(s):  
Yumi Watanabe ◽  
Hiroyuki Tsuchiya ◽  
Tomohiko Sakabe ◽  
Saori Matsuoka ◽  
Yuji Akechi ◽  
...  
Keyword(s):  
Er Stress ◽  
Stress Signaling ◽  
Ovarian Adenocarcinoma ◽  
Adenocarcinoma Cells

Ezrin Overexpression by Transformed Human Ovarian Surface Epithelial Cells, Ovarian Cleft Cells, and Serous Ovarian Adenocarcinoma Cells

2012 ◽  
Vol 19 (8) ◽  
pp. 797-805 ◽  
Author(s):  
Ahmed Fadiel ◽  
Zhaocong Chen ◽  
Emine Ulukus ◽  
Kaori Ohtani ◽  
Mehrangiz Hatami ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Ovarian Adenocarcinoma ◽  
Ovarian Surface ◽  
Adenocarcinoma Cells ◽  
Ovarian Surface Epithelial ◽  
Serous Ovarian Adenocarcinoma

Abstract 1155: Chemoresistance acquisition by ovarian adenocarcinoma cells due to microenvironment

2014 ◽  
Author(s):  
Benoit Thibault ◽  
Magali Castells ◽  
Delphine Mihas ◽  
Ludivine Genre ◽  
Cecile Gandy ◽  
...  
Keyword(s):  
Ovarian Adenocarcinoma ◽  
Adenocarcinoma Cells

scholarly journals Taxol Suppresses Dynamics of Individual Microtubules in Living Human Tumor Cells

1999 ◽  
Vol 10 (4) ◽  
pp. 947-959 ◽  
Author(s):  
Anne-Marie C. Yvon ◽  
Patricia Wadsworth ◽  
Mary Ann Jordan
Keyword(s):  
Cell Proliferation ◽  
Cell Lines ◽  
Mitotic Spindle ◽  
Dynamic Instability ◽  
Human Tumor ◽  
Mitotic Checkpoint ◽  
Microtubule Dynamics ◽  
Mitotic Spindles ◽  
Ovarian Adenocarcinoma ◽  
Adenocarcinoma Cells

Microtubules are intrinsically dynamic polymers, and their dynamics play a crucial role in mitotic spindle assembly, the mitotic checkpoint, and chromosome movement. We hypothesized that, inliving cells, suppression of microtubule dynamics is responsible for the ability of taxol to inhibit mitotic progression and cell proliferation. Using quantitative fluorescence video microscopy, we examined the effects of taxol (30–100 nM) on the dynamics of individual microtubules in two living human tumor cell lines: Caov-3 ovarian adenocarcinoma cells and A-498 kidney carcinoma cells. Taxol accumulated more in Caov-3 cells than in A-498 cells. At equivalent intracellular taxol concentrations, dynamic instability was inhibited similarly in the two cell lines. Microtubule shortening rates were inhibited in Caov-3 cells and in A-498 cells by 32 and 26%, growing rates were inhibited by 24 and 18%, and dynamicity was inhibited by 31 and 63%, respectively. All mitotic spindles were abnormal, and many interphase cells became multinucleate (Caov-3, 30%; A-498, 58%). Taxol blocked cell cycle progress at the metaphase/anaphase transition and inhibited cell proliferation. The results indicate that suppression of microtubule dynamics by taxol deleteriously affects the ability of cancer cells to properly assemble a mitotic spindle, pass the metaphase/anaphase checkpoint, and produce progeny.

Excision repair cross-complementation group 1 protein overexpression as a predictor of poor survival for high-grade serous ovarian adenocarcinoma

2010 ◽  
Vol 119 (2) ◽  
pp. 325-331 ◽  
Author(s):  
Stefanie Scheil-Bertram ◽  
Patricia Tylus-Schaaf ◽  
Andreas du Bois ◽  
Philipp Harter ◽  
Matthias Oppitz ◽  
...  
Keyword(s):  
Excision Repair ◽  
Complementation Group ◽  
High Grade ◽  
Protein Overexpression ◽  
Poor Survival ◽  
Ovarian Adenocarcinoma ◽  
Serous Ovarian Adenocarcinoma ◽  
Group 1

scholarly journals Human erythropoietin increases the pro-angiogenic potential of A2780 ovarian adenocarcinoma cells under hypoxic conditions

2013 ◽  
Vol 30 (3) ◽  
pp. 1455-1462 ◽  
Author(s):  
JÁN KRIŠKA ◽  
PETER SOLÁR ◽  
LENKA VARINSKÁ ◽  
ZUZANA SOLÁROVÁ ◽  
PATRÍCIA KIMÁKOVÁ ◽  
...  
Keyword(s):  
Ovarian Adenocarcinoma ◽  
Angiogenic Potential ◽  
Hypoxic Conditions ◽  
Human Erythropoietin ◽  
Adenocarcinoma Cells

The role of interferon-stimulated gene 15 in advanced stage high-grade serous ovarian adenocarcinoma

2012 ◽  
Vol 125 ◽  
pp. S140
Author(s):  
C. Tsai ◽  
T. Zaid ◽  
C. Co ◽  
M. Thompson ◽  
T. Yeung ◽  
...  
Keyword(s):  
High Grade ◽  
Advanced Stage ◽  
Ovarian Adenocarcinoma ◽  
Interferon Stimulated Gene 15 ◽  
Serous Ovarian Adenocarcinoma

Nonviral Vector for Efficient Gene Transfer to Human Ovarian Adenocarcinoma Cells

2002 ◽  
Vol 84 (1) ◽  
pp. 85-93 ◽  
Author(s):  
C.K. Kim ◽  
Kh.H. Haider ◽  
S.H. Choi ◽  
E.J. Choi ◽  
W.S. Ahn ◽  
...  
Keyword(s):  
Gene Transfer ◽  
Nonviral Vector ◽  
Ovarian Adenocarcinoma ◽  
Efficient Gene ◽  
Adenocarcinoma Cells

Immunophenotype and K-RAS Mutation in Mucinous Ovarian Adenocarcinoma With Mural Nodule of High-grade Sarcoma

2014 ◽  
Vol 33 (2) ◽  
pp. 186-190 ◽  
Author(s):  
Mohamed M. Desouki ◽  
Oluwole Fadare ◽  
Anisa Kanbour ◽  
Amal Kanbour-Shakir
Keyword(s):  
Mural Nodule ◽  
High Grade ◽  
Ovarian Adenocarcinoma ◽  
Ras Mutation ◽  
High Grade Sarcoma
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