Design and synthesis of novel 5-phenyl-N-piperidine ethanone containing 4,5-dihydropyrazole derivatives as potential antitumor agents

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We herein report a design and synthesis of new 1,3,5-triazine based pyrazole derivatives (5a-i) for anticancer activity targeting epidermal growth factor (EGFR) tyrosine kinase. The newly synthesized compounds were characterized...


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2010 ◽  
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