Synthesis, biological evaluation, and in silico studies of potential activators of apoptosis and carbonic anhydrase inhibitors on isatin-5-sulfonamide scaffold

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113997 ◽

2021 ◽

pp. 113997

Author(s):

Stepan K. Krymov ◽

Alexander M. Scherbakov ◽

Diana I. Salnikova ◽

Danila V. Sorokin ◽

Lyubov G. Dezhenkova ◽

...

Keyword(s):

Carbonic Anhydrase ◽

In Silico ◽

Biological Evaluation ◽

Carbonic Anhydrase Inhibitors ◽

In Silico Studies

Download Full-text

Synthesis, biological evaluation and in silico studies with 4-benzylidene-2-phenyl-5(4H)-imidazolone-based benzenesulfonamides as novel selective carbonic anhydrase IX inhibitors endowed with anticancer activity

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.103102 ◽

2019 ◽

Vol 90 ◽

pp. 103102 ◽

Cited By ~ 7

Author(s):

Wagdy M. Eldehna ◽

Mohamed A. Abdelrahman ◽

Alessio Nocentini ◽

Silvia Bua ◽

Sara T. Al-Rashood ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Anticancer Activity ◽

In Silico ◽

Biological Evaluation ◽

Carbonic Anhydrase Ix ◽

In Silico Studies

Download Full-text

Synthesis, biological evaluation and in silico studies of novel N-substituted phthalazine sulfonamide compounds as potent carbonic anhydrase and acetylcholinesterase inhibitors

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.103004 ◽

2019 ◽

Vol 89 ◽

pp. 103004 ◽

Cited By ~ 32

Author(s):

Cüneyt Türkeş ◽

Mustafa Arslan ◽

Yeliz Demir ◽

Liridon Çoçaj ◽

Arleta Rifati Nixha ◽

...

Keyword(s):

Carbonic Anhydrase ◽

In Silico ◽

Acetylcholinesterase Inhibitors ◽

Biological Evaluation ◽

In Silico Studies

Download Full-text

3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.111768 ◽

2019 ◽

Vol 184 ◽

pp. 111768 ◽

Cited By ~ 12

Author(s):

Mahmoud F. Abo-Ashour ◽

Wagdy M. Eldehna ◽

Alessio Nocentini ◽

Alessandro Bonardi ◽

Silvia Bua ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Anticancer Activity ◽

In Silico ◽

Biological Evaluation ◽

Carbonic Anhydrase Inhibitors

Download Full-text

Synthesis and Biological Evaluation of New 4-Thiazolidinone Derivatives as Carbonic Anhydrase Inhibitors

Letters in Organic Chemistry ◽

10.2174/1570178614666161230121658 ◽

2017 ◽

Vol 14 (2) ◽

pp. 80-85 ◽

Cited By ~ 3

Author(s):

Hayriye Genc ◽

Busra Ceken ◽

Cigdem Bilen ◽

Zubeyde Sackes ◽

Nahit Gencer ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Biological Evaluation ◽

Carbonic Anhydrase Inhibitors ◽

Synthesis And Biological Evaluation

Download Full-text

In-Silico Analysis of Chromone Containing Sulfonamide Derivatives as Human Carbonic Anhydrase Inhibitors

Medicinal Chemistry ◽

10.2174/1573406411309040015 ◽

2013 ◽

Vol 9 (4) ◽

pp. 608-616 ◽

Cited By ~ 3

Author(s):

Zaheer Ul-Haq ◽

Saman Usmani ◽

Uzma Mahmood ◽

Mariya al-Rashida ◽

Ghulam Abbas

Keyword(s):

Carbonic Anhydrase ◽

In Silico ◽

In Silico Analysis ◽

Carbonic Anhydrase Inhibitors ◽

Human Carbonic Anhydrase ◽

Silico Analysis

Download Full-text

Design, synthesis, characterization, in vitro and in silico evaluation of novel imidazo[2,1-b][1,3,4]thiadiazoles as highly potent acetylcholinesterase and non-classical carbonic anhydrase inhibitors

Bioorganic Chemistry ◽

10.1016/j.bioorg.2021.105009 ◽

2021 ◽

pp. 105009

Author(s):

Sercan Askin ◽

Hakan Tahtaci ◽

Cüneyt Türkeş ◽

Yeliz Demir ◽

Abdulilah Ece ◽

...

Keyword(s):

Carbonic Anhydrase ◽

In Silico ◽

Carbonic Anhydrase Inhibitors ◽

Design Synthesis

Download Full-text

Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2015.07.066 ◽

2015 ◽

Vol 23 (17) ◽

pp. 5311-5318 ◽

Cited By ~ 31

Author(s):

Adriano Mollica ◽

Roberto Costante ◽

Atilla Akdemir ◽

Simone Carradori ◽

Azzurra Stefanucci ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Docking Studies ◽

Biological Evaluation ◽

Carbonic Anhydrase Inhibitors

Download Full-text

Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.112019 ◽

2020 ◽

Vol 189 ◽

pp. 112019 ◽

Cited By ~ 12

Author(s):

Mohamed A. Said ◽

Wagdy M. Eldehna ◽

Alessio Nocentini ◽

Samar H. Fahim ◽

Alessandro Bonardi ◽

...

Keyword(s):

Antitumor Activity ◽

Carbonic Anhydrase ◽

Biological Evaluation ◽

Carbonic Anhydrase Inhibitors ◽

Design Synthesis ◽

Activity Design

Download Full-text

New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2020.115586 ◽

2020 ◽

Vol 28 (15) ◽

pp. 115586

Author(s):

Baijayantimala Swain ◽

Andrea Angeli ◽

Priti Singh ◽

Claudiu T. Supuran ◽

Mohammed Arifuddin

Keyword(s):

Carbonic Anhydrase ◽

Biological Evaluation ◽

Carbonic Anhydrase Inhibitors

Download Full-text

Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.103095 ◽

2019 ◽

Vol 90 ◽

pp. 103095 ◽

Cited By ~ 21

Author(s):

Mehtap Tugrak ◽

Halise Inci Gul ◽

Kenjiro Bandow ◽

Hiroshi Sakagami ◽

Ilhami Gulcin ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Anticancer Agents ◽

Mannich Bases ◽

Biological Evaluation ◽

Carbonic Anhydrase Inhibitors ◽

Synthesis And Biological Evaluation

Download Full-text