A new method for investigating osteoarthritis using Fast Field-Cycling nuclear magnetic resonance

Nuclear magnetic resonance (NMR) techniques are largely employed in several fields. As an example, NMR spectroscopy is used to provide structural and conformational information on pure systems, while affording quantitative evaluation on the number of nuclei in a given chemical environment. When dealing with relaxation, NMR allows understanding of molecular dynamics, i.e., the time evolution of molecular motions. The analysis of relaxation times conducted on complex liquid–liquid and solid–liquid mixtures is directly related to the nature of the interactions among the components of the mixture. In the present review paper, the peculiarities of low resolution fast field-cycling (FFC) NMR relaxometry in soil science are reported. In particular, the general aspects of the typical FFC NMR relaxometry experiment are firstly provided. Afterwards, a discussion on the main mathematical models to be used to “read” and interpret experimental data on soils is given. Following this, an overview on the main results in soil science is supplied. Finally, new FFC NMR-based hypotheses on nutrient dynamics in soils are described

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Comparative study of helical-cut notch–coil magnets for fast-field-cycling nuclear magnetic resonance

Canadian Journal of Physics ◽

10.1139/cjp-2013-0655 ◽

2014 ◽

Vol 92 (11) ◽

pp. 1430-1440 ◽

Cited By ~ 3

Author(s):

S. Kruber ◽

G.D. Farrher ◽

E. Anoardo

Keyword(s):

Magnetic Field ◽

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Magnet System ◽

Fast Switching ◽

Magnetic Field Homogeneity ◽

Field Cycling ◽

Fast Field ◽

The Magnetic Field ◽

Nuclear Magnetic

In this manuscript we describe an α-helical-cut notch–coil magnet system designed for fast switching of the magnetic field. An attempt was made to determine the extent to which such a magnet configuration can be efficiently used for fast-field-cycling (FFC) nuclear magnetic resonance (NMR) instruments. In addition to the typical technical requirements (high field-to-power ratio, adequate electric performance for fast-switching of the magnetic field and NMR-compatible magnetic field homogeneity), a tunable homogeneity within the sample volume and more uniform heat dissipation along the magnet body are included. A helical-cut notch–coil machined in metallic cylinders with external movable pieces was found to fit these requirements very well. A key factor for the optimization of the magnet parameters is the use of a novel calculation procedure based on a more realistic model that consider a magnet geometry with broken azimuthal symmetry. The aim of this paper is to theoretically compare the proposed geometry with other existing designs. No particular prototype is presented here. A clear understanding of the notch–coil performance was found to be an essential step for its further consideration as a potential autoadaptive (electronically controlled) magnet system for FFC applications.

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