A proteomic approach to receptor signaling: Molecular mechanisms and therapeutic implications derived from discovery of the dopamine D2 receptor signalplex

2007 ◽  
Vol 572 (2-3) ◽  
pp. 83-93 ◽  
Author(s):  
Nadine Kabbani ◽  
Robert Levenson
Keyword(s):  
Molecular Mechanisms ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Receptor Signaling ◽  
Therapeutic Implications ◽  
Dopamine D2 ◽  
Proteomic Approach

scholarly journals Dopamine D2 receptor signaling modulates mutant ataxin-1 S776 phosphorylation and aggregation

2010 ◽  
Vol 114 (3) ◽  
pp. 706-716 ◽  
Author(s):  
Scoty M. Hearst ◽  
Mariper E. Lopez ◽  
Qingmei Shao ◽  
Yong Liu ◽  
Parminder J. S. Vig
Keyword(s):  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Receptor Signaling ◽  
Dopamine D2

Modulation of Dopamine D2 Receptor Signaling by Actin-Binding Protein (ABP-280)

2000 ◽  
Vol 57 (3) ◽  
pp. 446-452 ◽  
Author(s):  
M. Li ◽  
J. C. Bermak ◽  
Z. W. Wang ◽  
Q. Y. Zhou
Keyword(s):  
Dopamine D2 Receptor ◽  
Binding Protein ◽  
D2 Receptor ◽  
Actin Binding ◽  
Receptor Signaling ◽  
Actin Binding Protein ◽  
Dopamine D2

scholarly journals Dopamine D2 receptor signaling modulates pancreatic beta cell circadian rhythms

2020 ◽  
Vol 113 ◽  
pp. 104551 ◽  
Author(s):  
Heather Wei ◽  
Rizaldy C. Zapata ◽  
Mariela Lopez-Valencia ◽  
Despoina Aslanoglou ◽  
Zachary J. Farino ◽  
...  
Keyword(s):  
Circadian Rhythms ◽  
Beta Cell ◽  
Dopamine D2 Receptor ◽  
Pancreatic Beta Cell ◽  
D2 Receptor ◽  
Receptor Signaling ◽  
Dopamine D2

scholarly journals The Influence of Hippocampal Dopamine D2 Receptors on Episodic Memory Is Modulated by BDNF and KIBRA Polymorphisms

2019 ◽  
Vol 31 (9) ◽  
pp. 1422-1429 ◽  
Author(s):  
Goran Papenberg ◽  
Nina Karalija ◽  
Alireza Salami ◽  
Micael Andersson ◽  
Jan Axelsson ◽  
...  
Keyword(s):  
Episodic Memory ◽  
Molecular Mechanisms ◽  
Dopamine D2 Receptor ◽  
Memory Performance ◽  
D2 Receptor ◽  
Interactive Effects ◽  
Candidate Gene Approach ◽  
Elderly Persons ◽  
Positive Effects ◽  
Dopamine D2

Episodic memory is a polygenic trait influenced by different molecular mechanisms. We used PET and a candidate gene approach to investigate how individual differences at the molecular level translate into between-person differences in episodic memory performance of elderly persons. Specifically, we examined the interactive effects between hippocampal dopamine D2 receptor (D2DR) availability and candidate genes relevant for hippocampus-related memory functioning. We show that the positive effects of high D2DR availability in the hippocampus on episodic memory are confined to carriers of advantageous genotypes of the brain-derived neurotrophic factor ( BDNF, rs6265) and the kidney and brain expressed protein ( KIBRA, rs17070145) polymorphisms. By contrast, these polymorphisms did not modulate the positive relationship between caudate D2DR availability and episodic memory.

scholarly journals Dopamine D2 Receptor Signaling in the Nucleus Accumbens Comprises a Metabolic–Cognitive Brain Interface Regulating Metabolic Components of Glucose Reinforcement

2017 ◽  
Vol 42 (12) ◽  
pp. 2365-2376 ◽  
Author(s):  
Michael Michaelides ◽  
Michael L Miller ◽  
Jennifer A DiNieri ◽  
Juan L Gomez ◽  
Elizabeth Schwartz ◽  
...  
Keyword(s):  
Nucleus Accumbens ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Receptor Signaling ◽  
Dopamine D2 ◽  
Brain Interface

α-Synuclein enhances dopamine D2 receptor signaling

2006 ◽  
Vol 1124 (1) ◽  
pp. 5-9 ◽  
Author(s):  
Sung Jae Kim ◽  
Sung Yul Kim ◽  
Young-Soon Na ◽  
Hyun Jung Lee ◽  
Kwang Chul Chung ◽  
...  
Keyword(s):  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Receptor Signaling ◽  
Dopamine D2

scholarly journals Enhanced GABA Transmission Drives Bradykinesia Following Loss of Dopamine D2 Receptor Signaling

Neuron ◽  
2016 ◽  
Vol 90 (4) ◽  
pp. 824-838 ◽  
Author(s):  
Julia C. Lemos ◽  
Danielle M. Friend ◽  
Alanna R. Kaplan ◽  
Jung Hoon Shin ◽  
Marcelo Rubinstein ◽  
...  
Keyword(s):  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Receptor Signaling ◽  
Dopamine D2 ◽  
Gaba Transmission
Sign in / Sign up

Export Citation Format

Share Document