Prediction of time-dependent CYP3A4 drug–drug interactions by physiologically based pharmacokinetic modelling: Impact of inactivation parameters and enzyme turnover

Physiologically Based ◽

Enzyme Turnover

Physiologically based pharmacokinetic modelling to support the clinical management of drug‐drug interactions with bictegravir

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.2221 ◽

2021 ◽

Author(s):

Felix Stader ◽

Manuel Battegay ◽

Catia Marzolini

Keyword(s):

Drug Interactions ◽

Clinical Management ◽

Physiologically Based

Physiologically based pharmacokinetic modelling andin vivo[I]/Kiaccurately predict P-glycoprotein-mediated drug-drug interactions with dabigatran etexilate

British Journal of Pharmacology ◽

10.1111/bph.12533 ◽

2014 ◽

Vol 171 (4) ◽

pp. 1043-1053 ◽

Cited By ~ 28

Author(s):

Yuansheng Zhao ◽

Zhe-Yi Hu

Keyword(s):

Drug Interactions ◽

Dabigatran Etexilate ◽

P Glycoprotein ◽

Physiologically Based

Prediction of drug-drug Interactions Between Various Antidepressants and Efavirenz or Boosted Protease Inhibitors Using a Physiologically Based Pharmacokinetic Modelling Approach

Clinical Pharmacokinetics ◽

10.1007/s40262-013-0056-7 ◽

2013 ◽

Vol 52 (7) ◽

pp. 583-592 ◽

Cited By ~ 35

Author(s):

Marco Siccardi ◽

Catia Marzolini ◽

Kay Seden ◽

Lisa Almond ◽

Anna Kirov ◽

...

Keyword(s):

Drug Interactions ◽

Protease Inhibitors ◽

Physiologically Based ◽

Modelling Approach

Prediction of pharmacokinetic drug-drug interactions causing atorvastatin-induced rhabdomyolysis using physiologically based pharmacokinetic modelling

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2019.109416 ◽

2019 ◽

Vol 119 ◽

pp. 109416 ◽

Cited By ~ 3

Author(s):

Size Li ◽

Yiqun Yu ◽

Zhiping Jin ◽

Yu Dai ◽

Haishu Lin ◽

...

Keyword(s):

Drug Interactions ◽

Physiologically Based ◽

Pharmacokinetic Drug

Physiologically based pharmacokinetic modelling prediction of the effects of dose adjustment in drug–drug interactions between levonorgestrel contraceptive implants and efavirenz-based ART

Journal of Antimicrobial Chemotherapy ◽

10.1093/jac/dkx515 ◽

2018 ◽

Vol 73 (4) ◽

pp. 1004-1012 ◽

Cited By ~ 11

Author(s):

Owain Roberts ◽

Rajith K R Rajoli ◽

David J Back ◽

Andrew Owen ◽

Kristin M Darin ◽

...

Keyword(s):

Drug Interactions ◽

Dose Adjustment ◽

Physiologically Based ◽

Contraceptive Implants

Erratum to: Prediction of Drug–Drug Interactions Between Various Antidepressants and Efavirenz or Boosted Protease Inhibitors Using a Physiologically Based Pharmacokinetic Modelling Approach

Clinical Pharmacokinetics ◽

10.1007/s40262-013-0066-5 ◽

2013 ◽

Vol 52 (7) ◽

pp. 613-614

Author(s):

Marco Siccardi ◽

Catia Marzolini ◽

Kay Seden ◽

Lisa Almond ◽

Anna Kirov ◽

...

Keyword(s):

Drug Interactions ◽

Protease Inhibitors ◽

Physiologically Based ◽

Modelling Approach

Physiologically‐Based Pharmacokinetic Modelling of Creatinine‐Drug Interactions in the Chronic Kidney Disease Population

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12566 ◽

2020 ◽

Vol 9 (12) ◽

pp. 695-706

Author(s):

Hiroyuki Takita ◽

Daniel Scotcher ◽

Rajkumar Chinnadurai ◽

Philip A. Kalra ◽

Aleksandra Galetin

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Drug Interactions ◽

Physiologically Based ◽

Chronic Kidney Disease Population

Physiologically Based Pharmacokinetic Modelling of Hyperforin to Predict Drug Interactions with St John’s Wort

Clinical Pharmacokinetics ◽

10.1007/s40262-019-00736-6 ◽

2019 ◽

Vol 58 (7) ◽

pp. 911-926 ◽

Cited By ~ 6

Author(s):

Jeffry Adiwidjaja ◽

Alan V. Boddy ◽

Andrew J. McLachlan

Keyword(s):

Drug Interactions ◽

St John’S Wort ◽

St John's Wort ◽

Physiologically Based

The application of physiologically based pharmacokinetic modelling to assess the impact of antiretroviral-mediated drug-drug interactions on piperaquine antimalarial therapy during pregnancy

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2087 ◽

2017 ◽

Vol 38 (8) ◽

pp. 464-478 ◽

Cited By ~ 10

Author(s):

Olusola Olafuyi ◽

Michael Coleman ◽

Raj K.S. Badhan

Keyword(s):

Drug Interactions ◽

Antimalarial Therapy ◽

Physiologically Based ◽

The Impact

Application of unbound liver-to-plasma concentration ratio to quantitative projection of cytochrome P450-mediated drug–drug interactions using physiologically based pharmacokinetic modelling approach

Xenobiotica ◽

10.1080/00498254.2018.1547461 ◽

2019 ◽

Vol 49 (11) ◽

pp. 1251-1259 ◽

Cited By ~ 4

Author(s):

Shinji Iwasaki ◽

Yohei Kosugi ◽

Andy Z.X. Zhu ◽

Sayaka Nakagawa ◽

Noriyasu Sano ◽

...

Keyword(s):

Cytochrome P450 ◽

Plasma Concentration ◽

Drug Interactions ◽

Concentration Ratio ◽

Physiologically Based ◽

Plasma Concentration Ratio ◽

Modelling Approach