Added value of pretreatment 18F-FDG PET/CT for staging of advanced gastric cancer: Comparison with contrast-enhanced MDCT

Aim: To perform a comprehensive analysis of discordances between contrast-enhanced CT (ceCT) and 18F-FDG PET/CT in the evaluation of the extra-cerebral treatment monitoring in patients with stage IV melanoma. Materials and methods: We conducted a retrospective monocentric observational study over a 3-year period in patients referred for 18F-FDG PET/CT and ceCT in the framework of therapy monitoring of immune checkpoint (ICIs) as of January 2017. Imaging reports were analyzed by two physicians in consensus. The anatomical site responsible for discordances, as well as induced changes in treatment were noted. Results: Eighty patients were included and 195 pairs of scans analyzed. Overall, discordances occurred in 65 cases (33%). Eighty percent of the discordances (52/65) were due to 18F-FDG PET/CT scans upstaging the patient. Amongst these discordances, 17/52 (33%) led to change in patient’s management, the most frequent being radiotherapy of a progressing site. ceCT represented 13/65 (20%) of discordances and induced changes in patients’ management in 2/13 cases (15%). The most frequent anatomical site involved was subcutaneous for 18F-FDG PET/CT findings and lung or liver for ceCT. Conclusions: Treatment monitoring with 18F-FDG PET/CT is more efficient than ceCT and has a greater impact in patient’s management.

Download Full-text

Comparison of liver SUV using unenhanced CT versus contrast-enhanced CT for attenuation correction in 18F-FDG PET/CT

Nuclear Medicine Communications ◽

10.1097/mnm.0000000000000086 ◽

2014 ◽

Vol 35 (5) ◽

pp. 472-477 ◽

Cited By ~ 3

Author(s):

Edwin E.G.W. ter Voert ◽

Hanneke W.M. van Laarhoven ◽

Peter J.M. Kok ◽

Wim J.G. Oyen ◽

Eric P. Visser ◽

...

Keyword(s):

Attenuation Correction ◽

Fdg Pet ◽

Unenhanced Ct ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Pet Ct ◽

Enhanced Ct ◽

18F Fdg ◽

Fdg Pet Ct

Download Full-text

The Added Value of [18F]FDG PET/CT in the Management of Invasive Fungal Infections

Diagnostics ◽

10.3390/diagnostics11010137 ◽

2021 ◽

Vol 11 (1) ◽

pp. 137

Author(s):

Alfred O. Ankrah ◽

Dina Creemers-Schild ◽

Bart de Keizer ◽

Hans C. Klein ◽

Rudi A. J. O. Dierckx ◽

...

Keyword(s):

Fdg Pet ◽

Fungal Infections ◽

Invasive Fungal Infections ◽

Added Value ◽

X Rays ◽

Imaging Studies ◽

Imaging Methods ◽

Pet Ct ◽

18F Fdg ◽

Fdg Pet Ct

Anatomy-based imaging methods are the usual imaging methods used in assessing invasive fungal infections (IFIs). [18F]FDG PET/CT has also been used in the evaluation of IFIs. We assessed the added value of [18F]FDG PET/CT when added to the most frequently used anatomy-based studies in the evaluation of IFIs. The study was conducted in two University Medical Centers in the Netherlands. Reports of [18F]FDG PET/CT and anatomy-based imaging performed within two weeks of the [18F]FDG PET/CT scan were retrieved, and the presence and sites of IFI lesions were documented for each procedure. We included 155 [18F]FDG PET/CT scans performed in 73 patients. A total of 216 anatomy-based studies including 80 chest X-rays, 89 computed tomography studies, 14 magnetic resonance imaging studies, and 33 ultrasound imaging studies were studied. The anatomy-based studies were concordant with the [18F]FDG PET/CT for 94.4% of the scans performed. [18F]FDG PET/CT detected IFI lesions outside of the areas imaged by the anatomy-based studies in 48.6% of the scans. In 74% of the patients, [18F]FDG PET/CT added value in the management of the IFIs.

Download Full-text