scholarly journals The Added Value of [18F]FDG PET/CT in the Management of Invasive Fungal Infections

Diagnostics ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 137
Author(s):  
Alfred O. Ankrah ◽  
Dina Creemers-Schild ◽  
Bart de Keizer ◽  
Hans C. Klein ◽  
Rudi A. J. O. Dierckx ◽  
...  

Anatomy-based imaging methods are the usual imaging methods used in assessing invasive fungal infections (IFIs). [18F]FDG PET/CT has also been used in the evaluation of IFIs. We assessed the added value of [18F]FDG PET/CT when added to the most frequently used anatomy-based studies in the evaluation of IFIs. The study was conducted in two University Medical Centers in the Netherlands. Reports of [18F]FDG PET/CT and anatomy-based imaging performed within two weeks of the [18F]FDG PET/CT scan were retrieved, and the presence and sites of IFI lesions were documented for each procedure. We included 155 [18F]FDG PET/CT scans performed in 73 patients. A total of 216 anatomy-based studies including 80 chest X-rays, 89 computed tomography studies, 14 magnetic resonance imaging studies, and 33 ultrasound imaging studies were studied. The anatomy-based studies were concordant with the [18F]FDG PET/CT for 94.4% of the scans performed. [18F]FDG PET/CT detected IFI lesions outside of the areas imaged by the anatomy-based studies in 48.6% of the scans. In 74% of the patients, [18F]FDG PET/CT added value in the management of the IFIs.

2017 ◽  
Vol 59 (5) ◽  
pp. 569-576 ◽  
Author(s):  
Robert M Kwee ◽  
Wouter AM Broos ◽  
Boudewijn Brans ◽  
Geert HIM Walenkamp ◽  
Jan Geurts ◽  
...  

Background The diagnosis of infected hip prosthesis is frequently not straightforward yet very important as it changes treatment. Purpose To retrospectively investigate the added value of 18F-FDG PET/CT to conventional tests including radiography, erythrocyte sedimentation rate (ESR)/C-reactive protein (CRP) testing, and joint aspiration, in diagnosing infected hip prosthesis. Material and Methods Seventy-eight hip prostheses of 78 patients (55% men; mean age = 66.5 years; age range = 30–85 years) with non-specific clinical presentation, i.e. no abscess or sinus tract communicating with the joint space at clinical examination, were analyzed. Cultures of intra-articular fluid and peri-implant tissues after revision surgery or clinical follow-up ≥6 months served as gold standard. Areas under the receiver operating characteristic curves (AUCs) of radiography, ESR/CRP testing, aspiration culture, and white blood cell (WBC) count without and with the addition of 18F-FDG PET/CT were compared. Results The addition of 18F-FDG PET/CT increased AUCs: for radiography with 0.212, P = 0.001; for ESR/CRP testing with 0.076, P = 0.072; for aspiration culture with 0.126, P = 0.032; and for aspiration WBC count with 0.191, P = 0.035. Conclusion This study shows that 18F-FDG PET/CT adds to individual conventional tests in diagnosing infected hip prosthesis. It may improve the preoperative planning and should therefore be considered in the diagnostic work-up. Future studies should define the exact place of 18F-FDG PET/CT in the diagnostic work-up of periprosthetic joint infection.


2016 ◽  
Vol 85 (5) ◽  
pp. 989-995 ◽  
Author(s):  
Yusuke Kawanaka ◽  
Kazuhiro Kitajima ◽  
Kazuhito Fukushima ◽  
Miya Mouri ◽  
Hiroshi Doi ◽  
...  

2020 ◽  
Vol 45 (4) ◽  
pp. 1075-1081
Author(s):  
Wujian Mao ◽  
Jun Zhou ◽  
Lin Qiu ◽  
Hongyan Yin ◽  
Hui Tan ◽  
...  

2012 ◽  
Vol 46 (3) ◽  
pp. 189-195 ◽  
Author(s):  
Eun Kyoung Choi ◽  
Ie Ryung Yoo ◽  
Hye Lim Park ◽  
Hyun Su Choi ◽  
Eun Ji Han ◽  
...  

2020 ◽  
Vol 13 (3) ◽  
pp. 195-203
Author(s):  
Mohsen Farsad

Background.: Accurate staging is crucial for the proper management of patients with nonsmall cell lung cancer, especially for choosing the best treatment strategy. Different Imaging methods are used to stage patients with non-small cell lung cancer. In the last two decades, FDG PET/CT is carried out in almost all the main Hospitals around the world in this setting. Objective: The aim of this paper is to focus on the value of integrated FDG PET/CT in the TNM staging of the non-small cell lung cancer. Methods: A non-systematic revision of the literature was performed in order to identify all papers about the role of FDG PET/CT in the evaluation of non-small cell lung cancer and to highlight the value of FDG PET/CT in this setting. Results: Many data are now available about this topic, including also randomized controlled trials. FDG PET/CT is of limited added value in the characterization of T status but it increases the diagnostic accuracy for the assessment of the nodal status. The main advantage of FDG PET/CT over conventional imaging methods is its higher sensitivity in identifying extra-thoracic metastases, especially bone and adrenal lesions. Conclusion: PET/CT with FDG should be included in the diagnostic work-up of patients with lung cancer, because it provides useful information for appropriate therapy.


Medicine ◽  
2015 ◽  
Vol 94 (27) ◽  
pp. e1124 ◽  
Author(s):  
Chih-Yung Chang ◽  
Cheng-Pei Chang ◽  
Chun-Che Shih ◽  
Bang-Hung Yang ◽  
Cheng-Yi Cheng ◽  
...  

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