Due to the growing advances in their temporal, spatial, and spectral resolutions, remotely sensed data continues to provide tools for a wide variety of environmental applications. This chapter presents the benefits and difficulties of Multi-Temporal Satellite Image (MTSI) for land use. Predicting land use changes using remote sensing is an area of interest that has been attracting increasing attention. Land use analysis from high temporal resolution remotely sensed images is important to promote better decisions for sustainable management land cover. The purpose of this book chapter is to review the background of using Hidden Markov Model (HMM) in land use change prediction, to discuss the difference on modeling using stationary as well as non-stationary data and to provide examples of both case studies (e.g. vegetation monitoring, urban growth).