Long-term outcomes after hepatectomy for recurrences after prior local ablation for hepatocellular carcinoma

2008 ◽  
Vol 34 (4) ◽  
pp. 433-438 ◽  
Author(s):  
J. Sakata ◽  
Y. Shirai ◽  
T. Wakai ◽  
K. Kaneko ◽  
K. Hatakeyama
Keyword(s):  
Hepatocellular Carcinoma ◽  
Long Term Outcomes ◽  
Local Ablation

Comparison of short- and long-term outcomes of patients with hepatocellular carcinoma undergoing surgical resection, local ablation, angiological treatment or palliation: Single center results over 35 years

2019 ◽  
Author(s):  
Valtteri Kairaluoma ◽  
Mira Karjalainen ◽  
Juha Saarnio ◽  
Jarmo Niemelä ◽  
Heikki Huhta ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Surgical Resection ◽  
Survival Rates ◽  
Confounding Factors ◽  
Single Center ◽  
Long Term Outcomes ◽  
Local Ablation ◽  
Short And Long Term ◽  
Overall Survival Rates

Abstract Background Hepatocellular carcinoma (HCC) is one leading cause of cancer mortality often presenting at inoperable stage. The aim of this study was to examine and compare surgically resected, locally ablated, angiologically treated and palliatively treated HCC patients’ short- and long-term outcomes in a single center over 35 year period. Methods All HCC diagnosed in Oulu University Hospital between 1983-2018 were identified from hospital records (n=273). Patients underwent hepatic resection (n=49), local ablation (RF, laser ablation or PEI; n=25), angiological treatments (TACE, TAE and SIRT; n=48) or palliative treatment (chemotherapy, best supportive care; n=151). Primary outcomes of the study were postoperative complications within 30 days after the operation, and short- (30- and 90-day) and long-term (1, 3 and 5-year) survival. Results were adjusted with sex, age, comorbidities, cirrhosis, Child-Pugh index points, ASA status, year of operation and stage. Results Surgically resected patients were younger than patients in other groups. Recurrence and local recidives occurred more often in local ablation group and in angiological treatment group (p<0.001). Surgical resection rate was 17.9%. Overall complication rates in surgical resection, local ablation and angiological group were 71.5%, 32.0% and 58.3%, (p<0.001). Major complications in respective groups occurred in 28.6%, 8.0% and 27.1%. Overall survival rates in surgical resection group were at 30 and 90 days, 1-, 3 and 5-years 95.9%, 95.9%, 85.1%, 59.0% and 51.2%. In local ablation group, respective overall survival rates were 100.0%, 100.0%, 86.1%, 43.1% and 18.8%, and in angiological group 95.8%, 93.6%, 56.1%, 26.3% and 6.6%. In cox regression model adjusted for confounding factors, local ablation and angiological treatment were significant risk factors for mortality. Prognosis was poor in palliatively treated patients. Conclusions Based on our study on Northern Finland population, the surgical resection of HCC seems to be the most effective treatment considering long-term survival and tumor recurrence after adjustment for confounding factors.

scholarly journals Long-term Outcomes after Laparoscopic Hepatectomy for Hepatocellular Carcinoma

HPB ◽  
2021 ◽  
Vol 23 ◽  
pp. S146
Author(s):  
D. Kilburn ◽  
D. Cavallucci ◽  
U. Leung ◽  
M. Siriwardhane ◽  
R. Bryant ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Laparoscopic Hepatectomy ◽  
Long Term Outcomes

scholarly journals Is the use of intra-operative blood salvage autotransfusion in hepatocellular carcinoma liver transplantation safe? A comparative analysis of long-term outcomes

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S366
Author(s):  
Kah Wai Lai ◽  
Jarrod Tan ◽  
Glenn Bonney ◽  
Iyer Shridhar ◽  
Krishnakumar Madhavan ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Comparative Analysis ◽  
Long Term Outcomes ◽  
Blood Salvage

FIB-4 Index is a Predictor of Background Liver Fibrosis and Long-Term Outcomes After Curative Resection of Hepatocellular Carcinoma

2016 ◽  
Vol 23 (S4) ◽  
pp. 467-474 ◽  
Author(s):  
Yukiyasu Okamura ◽  
Ryo Ashida ◽  
Yusuke Yamamoto ◽  
Takaaki Ito ◽  
Teiichi Sugiura ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Fibrosis ◽  
Curative Resection ◽  
Long Term Outcomes

scholarly journals Age-adjusted Charlson-comorbidity Index Predicts Short-term and Long-term Outcomes after Hepatic Resection of Hepatocellular Carcinoma

HPB ◽  
2021 ◽  
Vol 23 ◽  
pp. S33
Author(s):  
H. Shinkawa ◽  
S. Tanaka ◽  
S. Takemura ◽  
R. Amano ◽  
K. Kimura ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatic Resection ◽  
Charlson Comorbidity Index ◽  
Long Term Outcomes ◽  
Short Term ◽  
Comorbidity Index

Long-Term Outcomes of Hepatitis-C-Infected Patients Achieving a Sustained Virological Response and Undergoing Radical Treatment for Hepatocellular Carcinoma

Oncology ◽  
2016 ◽  
Vol 90 (3) ◽  
pp. 167-175 ◽  
Author(s):  
Hideo Kunimoto ◽  
Kenji Ikeda ◽  
Yushi Sorin ◽  
Shunichiro Fujiyama ◽  
Yusuke Kawamura ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis C ◽  
Sustained Virological Response ◽  
Virological Response ◽  
Long Term Outcomes ◽  
Radical Treatment

scholarly journals Meta-analysis of short- and long-term outcomes after pure laparoscopic versus open liver surgery in hepatocellular carcinoma patients

2018 ◽  
Vol 33 (5) ◽  
pp. 1491-1507 ◽  
Author(s):  
Jan Witowski ◽  
Mateusz Rubinkiewicz ◽  
Magdalena Mizera ◽  
Michał Wysocki ◽  
Natalia Gajewska ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Surgery ◽  
Meta Analysis ◽  
Long Term Outcomes ◽  
Short And Long Term
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