scholarly journals Role of Adipose Tissue and Skeletal Muscle in Atherosclerotic Occlusive Disease (Peripheral Arterial Disease and Carotid Arterial Disease) and in Central Hemodynamics

2019 ◽  
Vol 58 (6) ◽  
pp. e802
Author(s):  
Joana Ferreira ◽  
Cristina Silva ◽  
Cristina Cunha ◽  
Isabel Vila ◽  
Pedro Cunha ◽  
...  
2020 ◽  
Vol 25 (Supplement 1) ◽  
pp. S56
Author(s):  
Joana Ferreira ◽  
Pedro Cunha ◽  
Alexandre Carneiro ◽  
Cristina Cunha ◽  
Cristina Silva ◽  
...  

2021 ◽  
Vol 22 (7) ◽  
pp. 3601
Author(s):  
Goren Saenz-Pipaon ◽  
Esther Martinez-Aguilar ◽  
Josune Orbe ◽  
Arantxa González Miqueo ◽  
Leopoldo Fernandez-Alonso ◽  
...  

Peripheral arterial disease (PAD) of the lower extremities is a chronic illness predominantly of atherosclerotic aetiology, associated to traditional cardiovascular (CV) risk factors. It is one of the most prevalent CV conditions worldwide in subjects >65 years, estimated to increase greatly with the aging of the population, becoming a severe socioeconomic problem in the future. The narrowing and thrombotic occlusion of the lower limb arteries impairs the walking function as the disease progresses, increasing the risk of CV events (myocardial infarction and stroke), amputation and death. Despite its poor prognosis, PAD patients are scarcely identified until the disease is advanced, highlighting the need for reliable biomarkers for PAD patient stratification, that might also contribute to define more personalized medical treatments. In this review, we will discuss the usefulness of inflammatory molecules, matrix metalloproteinases (MMPs), and cardiac damage markers, as well as novel components of the liquid biopsy, extracellular vesicles (EVs), and non-coding RNAs for lower limb PAD identification, stratification, and outcome assessment. We will also explore the potential of machine learning methods to build prediction models to refine PAD assessment. In this line, the usefulness of multimarker approaches to evaluate this complex multifactorial disease will be also discussed.


Author(s):  
Aditya K. Gupta ◽  
Madhulika A. Gupta ◽  
Richard C. Summerbell ◽  
Elizabeth A. Cooper ◽  
Nellie Konnikov ◽  
...  

2005 ◽  
Vol 96 (7) ◽  
pp. 996-1001 ◽  
Author(s):  
Annelies E. Aquarius ◽  
Johan Denollet ◽  
Jaap F. Hamming ◽  
Jolanda De Vries

2017 ◽  
Vol 36 (6) ◽  
Author(s):  
Gregory C. Makris ◽  
Pavlina Chrysafi ◽  
Mark Little ◽  
Rafiuddin Patel ◽  
Mark Bratby ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document