scholarly journals Bayesian meta-analysis of inter-phenotypic differences in human serum paraoxonase-1 activity for chemical risk assessment

2020 ◽  
Vol 138 ◽  
pp. 105609 ◽  
Author(s):  
K. Darney ◽  
E.E.J. Kasteel ◽  
F.M. Buratti ◽  
L. Turco ◽  
S. Vichi ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Human Serum ◽  
Meta Analysis ◽  
Paraoxonase 1 ◽  
Chemical Risk ◽  
Phenotypic Differences ◽  
Chemical Risk Assessment ◽  
Serum Paraoxonase

scholarly journals Inter-ethnic differences in CYP3A4 metabolism: A Bayesian meta-analysis for the refinement of uncertainty factors in chemical risk assessment

2019 ◽  
Vol 12 ◽  
pp. 100092 ◽  
Author(s):  
Keyvin Darney ◽  
Emanuela Testai ◽  
Franca M. Buratti ◽  
Emma Di Consiglio ◽  
Emma E.J. Kasteel ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Ethnic Differences ◽  
Meta Analysis ◽  
Uncertainty Factors ◽  
Chemical Risk ◽  
Chemical Risk Assessment

scholarly journals A critical review on human serum Paraoxonase-1 in the literature: truths and misconceptions

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Michael Mackness ◽  
Eser Yildirim Sozmen
Keyword(s):  
Heart Disease ◽  
Experimental Design ◽  
Human Serum ◽  
Critical Review ◽  
Neurological Diseases ◽  
Rapid Expansion ◽  
Paraoxonase 1 ◽  
Serum Paraoxonase ◽  
Inflammatory Component ◽  
Biomedical Fields

AbstractHuman serum paraoxonase 1 (PON1) appears to play an important role in the development of a large variety of diseases with an inflammatory component including heart disease, diabetes, rheumatic diseases, neurological diseases and cancer. As such PON1 research is rapidly expanding into new biomedical fields. Unfortunately, this rapid expansion has resulted in a number of problems due to poor experimental design and the spreading of misconceptions in the literature. This review seeks to describe the basic properties of PON1 and the problems and misconceptions that have arisen.

scholarly journals Chemical risk assessment based on in vitro and human biomonitoring data: A case study on thyroid toxicants

2019 ◽  
Vol 15 ◽  
pp. 8-17 ◽  
Author(s):  
Hanna K.L. Johansson ◽  
Julie Boberg ◽  
Marianne Dybdahl ◽  
Marta Axelstad ◽  
Anne Marie Vinggaard
Keyword(s):  
Risk Assessment ◽  
Human Biomonitoring ◽  
Chemical Risk ◽  
Chemical Risk Assessment

CRAMD — A Database for Validation of Models Used in Chemical Risk Assessment

1995 ◽  
pp. 429-439
Author(s):  
R. Kakko ◽  
H. Länsipuro ◽  
A. Lancia ◽  
I. C. Ziomas ◽  
P. M. Foster
Keyword(s):  
Risk Assessment ◽  
Chemical Risk ◽  
Chemical Risk Assessment ◽  
Validation Of Models
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