Polycyclic aromatic compounds in urban soils of Stockholm City: Occurrence, sources and human health risk assessment

2020 ◽  
Vol 182 ◽  
pp. 108989 ◽  
Author(s):  
Kristian Dreij ◽  
Lisa Lundin ◽  
Florane Le Bihanic ◽  
Staffan Lundstedt
2008 ◽  
Vol 24 (suppl 4) ◽  
pp. a569-s580 ◽  
Author(s):  
Sérgio Silveira Franco ◽  
Adelaide Cássia Nardocci ◽  
Wanda Maria Risso Günther

Polycyclic aromatic hydrocarbons (PAH) are widely distributed in the environment, and some are carcinogenic to human beings. The study of biomarkers has helped clarify the nature and magnitude of the human health risks posed by such substances. This article provides a review of the state-of-the-art on PAH biomarkers for human health risk assessment and also discusses their applicability within the context of environmental management in Brazil. The article discusses the methodologies for determination of some biomarkers such as 1-hydroxypyrene and PAH-DNA adducts. Cytogenetic markers, frequency of chromosomal aberrations, and micronucleus induction were considered for the evaluation of cancer risk. The current stage of studies on validation of such biomarkers was also approached.


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