Maternal ADHD medication use during pregnancy and the risk of ADHD in children: Importance of genetic predispositions and impact of using a sibling analysis

2021 ◽  
Vol 44 ◽  
pp. 66-78
Author(s):  
Maxim Lemelin ◽  
Odile Sheehy ◽  
Jin-Ping Zhao ◽  
Anick Bérard
2014 ◽  
Vol 205 (4) ◽  
pp. 291-297 ◽  
Author(s):  
Cédric Galéra ◽  
Jean-Baptiste Pingault ◽  
Grégory Michel ◽  
Manuel-Pierre Bouvard ◽  
Maria Melchior ◽  
...  

BackgroundThe impact of longitudinal psychiatric comorbidity, parenting and social characteristics on attention-deficit hyperactivity disorder (ADHD) medication use is still poorly understood.AimsTo assess the baseline and longitudinal influences of behavioural and environmental factors on ADHD medication use.MethodSurvival regressions with time-dependent covariates were used to model data from a population-based longitudinal birth cohort. The sample (n = 1920) was assessed from age 5 months to 10 years. Measures of children's psychiatric symptoms, parenting practices and social characteristics available at baseline and during follow-up were used to identify individual and family-level features associated with subsequent use of ADHD medication.ResultsUse of ADHD medication ranged from 0.2 to 8.6% between ages 3.5 to 10 years. Hyperactivity–inattention was the strongest predictor of medication use (hazard ratio (HR) = 2.75, 95% CI 2.35–3.22). Among all social variables examined, low maternal education increased the likelihood of medication use (HR = 2.09, 95% CI 1.38–3.18) whereas immigrant status lowered this likelihood (HR = 0.40, 95% CI 0.17–0.92).ConclusionsBeyond ADHD symptoms, the likelihood of receiving ADHD medication is predicted by social variables and not by psychiatric comorbidity or by parenting. This emphasises the need to improve global interventions by offering the same therapeutic opportunities (including medication) as those received by the rest of the population to some subgroups (i.e. immigrants) and by diminishing possible unnecessary prescriptions.


2014 ◽  
Vol 29 (4) ◽  
pp. 571-578 ◽  
Author(s):  
E.E. Krabbe ◽  
E.D. Thoutenhoofd ◽  
M. Conradi ◽  
S.J. Pijl ◽  
L. Batstra

2007 ◽  
Author(s):  
Scott P. Novak ◽  
Larry A. Kroutil ◽  
Rick L. Williams ◽  
David L. Van Brunt

2020 ◽  
pp. 108705471990023
Author(s):  
Mao-Hsiu Hua ◽  
Kai-Lin Huang ◽  
Ju-Wei Hsu ◽  
Ya-Mei Bai ◽  
Tung-Ping Su ◽  
...  

Objective: ADHD potentially leads to risky sexual behaviors, and is considered a major risk factor for early pregnancy (EP). However, the association between ADHD and subsequent EP remains unknown. Method: Seven thousand five hundred five adolescents with ADHD and 30,020 age- and sex-matched individuals without ADHD were enrolled from 2001 to 2009 and were followed until the end of 2011. Adolescents who developed any pregnancy (at age ≤30 years) or EP (at age <20 years) during the follow-up period were identified. Results: Adolescents with ADHD were found to be prone to pregnancy (hazard ratio [HR] = 1.27) and EP (HR = 2.30) compared with those without ADHD. Long-term ADHD medication use was related to a lower risk of subsequent any pregnancy (HR = 0.72) and EP (HR = 0.69). Conclusion: Adolescents with ADHD had an increased risk of any pregnancy and EP compared with their non-ADHD counterparts. Long-term ADHD medication use was associated with a lower subsequent EP risk.


2011 ◽  
Vol 27 (sup2) ◽  
pp. 13-22 ◽  
Author(s):  
Jamie C. Barner ◽  
Star Khoza ◽  
Abiola Oladapo

2014 ◽  
Vol 37 ◽  
pp. 137-151 ◽  
Author(s):  
Søren Dalsgaard ◽  
Helena Skyt Nielsen ◽  
Marianne Simonsen

2016 ◽  
Vol 51 (4) ◽  
pp. 508-516 ◽  
Author(s):  
Ashley M. Ramos ◽  
Brittney Becker ◽  
Julie A. Biemer ◽  
Lindsay Clark ◽  
Sherecce Fields ◽  
...  

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