Surgical Care, Morbidity, Mortality and Follow-up after Nephrectomy for Renal Cancer with Extension of Tumor Thrombus into the Inferior Vena Cava: Retrospective Study Since 1990s

2006 ◽  
Vol 50 (2) ◽  
pp. 302-310 ◽  
Author(s):  
Jérôme Rigaud ◽  
Jean-François Hetet ◽  
Guillaume Braud ◽  
Simon Battisti ◽  
Loïc Le Normand ◽  
...  
2015 ◽  
Vol 16 (5) ◽  
pp. 657-661 ◽  
Author(s):  
Raquibul Hannan ◽  
Vitaly Margulis ◽  
Stephen G Chun ◽  
Nathan Cannon ◽  
D W Nathan Kim ◽  
...  

2021 ◽  
Author(s):  
Zhuo Liu ◽  
Yuxuan Li ◽  
Guodong Zhu ◽  
Liyuan Ge ◽  
Shiying Tang ◽  
...  

Abstract Background: To summarize the surgical technique and clinicopathological features of recurrent renal tumor thrombus in inferior vena cava (IVC) after surgery.Methods: We retrospectively analyzed the clinicopathological data of nine patients with recurrent renal tumor thrombus in IVC after surgery, who were admitted to Peking University Third Hospital between November 2015 and March 2021. Results: Among the nine patients, six patients (66.7%) developed recurrent tumor thrombus in the IVC after radical nephrectomy; two cases (22.2%) were recurrent tumor thrombus in the IVC after partial nephrectomy. One patient (11.1%) underwent partial nephrectomy first and radical nephrectomy for the second time. The recurrence of tumor thrombus in the IVC occurred after the operation. All the nine patients underwent open surgery for IVC thrombectomy. Eight patients (88.9 %) were operated smoothly. Among these eight patients, six patients (75%) underwent IVC segmental resection, and two patients (25%) underwent IVC thrombectomy. Another patient underwent IVC tumor thrombus exclusion. Median operative time was 380 (IQR: 338.5–540.5) min. Median estimated intraoperative blood loss was 1200 (IQR: 600–2250) ml. According to the modified Clavien classification system, one patient had grade I complications, three patients had grade II complications, and one patient had grade IVa complications. During a 20-months (range, 2-58 months) follow-up, tumor-specific death occurred in three patients and distant metastasis occurred in six patients.Conclusions: The operation of recurrent renal tumor thrombus in IVC after surgery is difficult. For patients with high-risk renal cell carcinoma, more close follow-up should be conducted after operation.


2021 ◽  
Vol 100 (2) ◽  

Introduction: Renal cancer is unique for many reasons. One reason is that renal cell carcinoma can grow directly into the drainage veins of the kidney, which enter the inferior vena cava leading to the heart. This growth of tumor cells into the veins is called a tumor thrombus and is a locally aggressive renal cancer. The present article informs about the experience of our cardiac surgery department together with the transplant surgery department in successful surgical removal of a kidney with tumor, with invasion into the inferior vena cava, right atrium of the heart and pulmonary artery in two case reports. Case Reports: A 32 years old female without significant history, with suddenly evolving dyspnea was urgently admitted to hospital. Her condition was suspected to be caused by pulmonary artery embolisation. The diagnosis was confirmed by CT scan which revealed unknown tumor mass of the right kidney and tumor embolisation in inferior vena cava and pulmonary artery. The patient was urgently operated by a vascular surgeon and cardiothoracic surgeon. They successfully performed left radical nephrectomy and total thromboembolectomy of the tumorous masses from vena cava inferior and pulmonary artery. The postoperative course was without complications, postoperative CT revealed no residual masses, and the patient was discharged in a good condition from the hospital. A 58 years old male with arterial hypertension suffered from orchiepididymitis. CT scan showed a tumor of the left kidney with propagation of tumorous masses to inferior vena cava and pulmonary artery. In elective surgery the vascular surgeon and cardiothoracic surgeon successfully performed left radical nephrectomy with total thromboembolectomy of the tumorous masses from inferior vena cava and pulmonary artery. After surgery a temporary paralytic ileus and an episode of atrial fibrillation occurred. Both are common postoperative complications related to the given surgical procedure. Follow-up CT scan showed no residual tumor or thrombus in inferior vena cava and pulmonary artery. Echocardiography revealed persistent dilation of right compartments of the heart with good systolic functions of both ventricles. The patient was discharged from hospital in a good condition. Conclusion: Surgical removal of renal tumor and tumor thrombus – radical nephrectomy with tumor thrombectomy – can be a curative treatment and can ensure long-term survival of the patient. Depending on the extent of the tumor thrombus, these operations can be performed in different ways – mini-invasive, robotic or open. When open surgery is used, it is possible to perform the procedure with or without extracorporeal circulation (cardiopulmonary bypass – CPB) depending on the extent of the disease.


1989 ◽  
Vol 50 (6) ◽  
pp. 1227-1234
Author(s):  
Satoshi KAMADA ◽  
Tadanori KAWADA ◽  
Hiroyuki ABE ◽  
Takashi MIEDA ◽  
Saburou HINATA ◽  
...  

2021 ◽  
Vol 6 (2) ◽  
Author(s):  
Ocampo MA ◽  
Capera C ◽  
Gonzalez MC ◽  
Salgado JM ◽  
Donoso W

Angiomyolipoma (AML) is a frequent benign renal tumor, corresponding to 0.3-3% of all renal masses. Eighty percent of AML occur sporadically; however, 10% have a hereditary component. We describe the case of a 41-year-old female patient with left abdominal pain associated with emesis, diarrheal stools, and dysuria. Upon admission, a computed tomography scan showed a left renal mass with tumor thrombus extending into the left renal vein and inferior vena cava (IVC). The patient underwent an open left radical nephrectomy plus thrombectomy. At 6months of follow-up, the patient is without tumor recurrence and asymptomatic.


Kanzo ◽  
2016 ◽  
Vol 57 (5) ◽  
pp. 205-212
Author(s):  
Takaaki Sugihara ◽  
Masahiko Koda ◽  
Toshiaki Okamoto ◽  
Kenichi Miyoshi ◽  
Tomomitsu Matono ◽  
...  

2020 ◽  
Author(s):  
Zhigang Chen ◽  
Bin Yang ◽  
Liyuan Ge ◽  
Fan Zhang ◽  
Xiaojun Tian ◽  
...  

Abstract Background: To present our initial experiences on the left radical nephrectomy (RN) and Mayo II-III IVC thrombectomy (IVCTE) using modified inferior vena cava (IVC) clamping technique. Methods: From November 2016 to July 2018, eight left renal cell carcinoma (RCC) patients with inferior vena cava tumor thrombus (IVCTT) underwent retroperitoneal laparoscopic RN and IVCTE using the modified IVC clamping technique. During the IVCTE, the infrarenal IVC, right renal artery, right renal vein were clamped sequentially, then the cephalic IVC of the tumor thrombus was clamped immediately after the thrombus was removed.Results: According to the preoperative plans, all 8 operations were completed successfully without perioperative mortality. Median operative time was 438 min (343-573 min). Median IVC blocking time was 18 min (12-28min), and median warm ischemia time (WIT) for the right kidney was 19min (14-28min). Median estimated intraoperative blood loss was 1107mL (50-6000 ml). Some 50% of patients required an intraoperative blood transfusion. Median length of hospital stay was 12.9 days (6-39). Early postoperative complications occurred in 2 cases, 1 was Clavien class II, another was Clavien class IVa. All 8 patients were followed up continually with a median follow-up period of 16 months (5-25 months). During the mean follow-up period, three patients developed metastatic disease.Conclusions: Modified IVC clamping technique, which is feasible and safe for experienced surgeons in selected patients, can simplify the procedures left RN and Mayo II-III IVCTE.


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