Role of Endoscopic Therapy Plus Intravenous Proton Pump Inhibitor in Uremic Patients with High-Risk Peptic Ulcer Bleeding. Preliminary Report of a Case-Controlled Study

2009 ◽  
Vol 69 (5) ◽  
pp. AB179-AB180
Author(s):  
Gaun-Ying Tseng
Keyword(s):  
Peptic Ulcer ◽  
High Risk ◽  
Proton Pump Inhibitor ◽  
Proton Pump ◽  
Preliminary Report ◽  
Endoscopic Therapy ◽  
Ulcer Bleeding ◽  
Controlled Study ◽  
Peptic Ulcer Bleeding

UPDATE ON ENDOSCOPIC MANAGEMENT OF PEPTIC ULCER BLEEDING

2012 ◽  
pp. 5-11
Author(s):  
Ngoc Quy Hue Dang ◽  
Van Huy Tran
Keyword(s):  
Peptic Ulcer ◽  
High Risk ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Endoscopic Therapy ◽  
Active Bleeding ◽  
Ulcer Bleeding ◽  
Endoscopic Management ◽  
High Dose ◽  
Peptic Ulcer Bleeding

Peptic ulcer bleeding is a common medical emergency and still a potentially fatal condition. It is the best managed using a multidisciplinary approach by a team with medical, endoscopic and surgical expertise. Appropriate resuscitation followed by early endoscopy for diagnosis and treatment are of major importance in these patients. Endoscopy is recommended within 24 h of presentation. Endoscopic therapy is indicated for patients with high-risk stigmata, in particular those with active bleeding and visible vessels. A combination of proton pump inhibitors and endoscopic therapy (using a combination of injection and mechanical hemostasis) offers the best chance of hemostasis for those with active bleeding ulcers. The application of an ulcer-covering hemospray is a new promising tool. High dose proton pump inhibitors should be administered intravenously for 72 h in high-risk patients. Helicobacter pylori should be tested for in all patients with peptic ulcer bleeding and eradicated if positive

Effect of intravenous proton pump inhibitor regimens and timing of endoscopy on clinical outcomes of peptic ulcer bleeding

2012 ◽  
Vol 27 (9) ◽  
pp. 1473-1479 ◽  
Author(s):  
Na Liu ◽  
Lili Liu ◽  
HongBo Zhang ◽  
Prakash Chandra Gyawali ◽  
Dexin Zhang ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Proton Pump Inhibitor ◽  
Clinical Outcomes ◽  
Proton Pump ◽  
Ulcer Bleeding ◽  
Peptic Ulcer Bleeding
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