Tu2049 Long term Outcomes of PerOral Endoscopic Myotomy (POEM) in Achalasia patients With a minimum follow-up of 2 years: A multicenter study

2016 ◽  
Vol 83 (5) ◽  
pp. AB628 ◽  
Author(s):  
Saowanee Ngamruengphong ◽  
Haruhiro Inoue ◽  
Amol Bapaye ◽  
Michael Ujiki ◽  
Lava Y. Patel ◽  
...  
Keyword(s):  
Multicenter Study ◽  
Peroral Endoscopic Myotomy ◽  
Long Term Outcomes ◽  
Endoscopic Myotomy

One-year results of gastric peroral endoscopic myotomy for refractory gastroparesis: a French multicenter study

Endoscopy ◽  
2020 ◽  
Author(s):  
Olivier Ragi ◽  
Jérémie Jacques ◽  
Julien Branche ◽  
Sarah Leblanc ◽  
Geoffroy Vanbiervliet ◽  
...  
Keyword(s):  
Success Rate ◽  
Multicenter Study ◽  
Clinical Success ◽  
Clinical Success Rate ◽  
Peroral Endoscopic Myotomy ◽  
Gastric Retention ◽  
Endoscopic Myotomy ◽  
Cardinal Symptom

Abstract Background: Data on the long-term outcomes of gastric peroral endoscopic myotomy (G-POEM) for refractory gastroparesis are lacking. We report the results of a large multicenter long-term follow-up study of G-POEM for refractory gastroparesis. Methods: This was a retrospective multicenter study of all G-POEM operations performed in seven expert French centers for refractory gastroparesis with at least 1 year of follow-up. The primary endpoint was the 1-year clinical success rate, defined as at least a 1-point improvement in the Gastroparesis Cardinal Symptom Index (GCSI). Results: 76 patients were included (60.5 % women; age 56 years). The median symptom duration was 48 months. The median gastric retention at 4 hours (H4) before G-POEM was 45 % (interquartile range [IQR] 29 % – 67 %). The median GCSI before G-POEM was 3.6 (IQR 2.8 – 4.0). Clinical success was achieved in 65.8 % of the patients at 1 year, with a median rate of reduction in the GCSI score of 41 %. In logistic regression analysis, only a high preoperative GCSI satiety subscale score was predictive of clinical success (odds ratio [OR] 3.41, 95 % confidence interval [CI] 1.01 – 11.54; P = 0.048), while a high rate of gastric retention at H4 was significantly associated with clinical failure (OR 0.97, 95 %CI 0.95 – 1.00; P = 0.03). Conclusions: The results confirm the efficacy of G-POEM for the treatment of refractory gastroparesis, as evidenced by a 65.8 % clinical success rate at 1 year. Although G-POEM is promising, prospective sham-controlled trials are urgently needed to confirm its efficacy and identify the patient populations who will benefit most from this procedure.

scholarly journals Long-term outcomes of peroral endoscopic myotomy in achalasia patients with a minimum follow-up of 7 years

2020 ◽  
Vol 133 (8) ◽  
pp. 996-998
Author(s):  
Wen-Gang Zhang ◽  
Ning-Li Chai ◽  
Ya-Qi Zhai ◽  
En-Qiang Linghu ◽  
Hui-Kai Li
Keyword(s):  
Peroral Endoscopic Myotomy ◽  
Long Term Outcomes ◽  
Endoscopic Myotomy

470 LONG TERM OUTCOMES OF PER-ORAL ENDOSCOPIC MYOTOMY IN ACHALASIA PATIENTS WITH A MINIMUM FOLLOW-UP OF 6 YEARS: A MULTICENTER STUDY

2019 ◽  
Vol 89 (6) ◽  
pp. AB82-AB83
Author(s):  
Jad P. AbiMansour ◽  
Hitomi Minami ◽  
Pietro Familiari ◽  
Rosario Landi ◽  
Guido Costamagna ◽  
...  
Keyword(s):  
Multicenter Study ◽  
Long Term Outcomes ◽  
Per Oral Endoscopic Myotomy ◽  
Endoscopic Myotomy ◽  
Per Oral

scholarly journals Tu1195 LONG-TERM OUTCOMES OF PER-ORAL ENODOSCOPIC MYOTOMY IN ACHALASIA PATIENTS WITH A MINIMUM FOLLOW-UP OF 4 YEARS: A MULTICENTER STUDY

2018 ◽  
Vol 87 (6) ◽  
pp. AB564-AB565
Author(s):  
Olaya I. Brewer Gutierrez ◽  
Pietro Familiari ◽  
Guido Costamagna ◽  
Stefan Seewald ◽  
Shivangi Dorwat ◽  
...  
Keyword(s):  
Multicenter Study ◽  
Long Term Outcomes ◽  
Per Oral

Tu1204 Peroral Endoscopic Myotomy (Poem) in Patients With or Without Prior Heller Myotomy: Comparing Long-Term Outcomes in a Large Us Single Center Cohort

2017 ◽  
Vol 85 (5) ◽  
pp. AB581
Author(s):  
Stavros N. Stavropoulos ◽  
Xiaocen Zhang ◽  
Rani J. Modayil ◽  
Krishna C. Gurram ◽  
Collin E. Brathwaite ◽  
...  
Keyword(s):  
Heller Myotomy ◽  
Peroral Endoscopic Myotomy ◽  
Single Center ◽  
Long Term Outcomes ◽  
Endoscopic Myotomy

Long-Term Efficacy of Peroral Endoscopic Myotomy for Patients with Achalasia: Outcomes with a Median Follow-Up of 36 Months

2018 ◽  
Vol 64 (3) ◽  
pp. 803-810 ◽  
Author(s):  
Chenghai He ◽  
Meng Li ◽  
Bin Lu ◽  
Xiao Ying ◽  
Chen Gao ◽  
...  
Keyword(s):  
Peroral Endoscopic Myotomy ◽  
Term Efficacy ◽  
Endoscopic Myotomy

scholarly journals Diarrhoea, enteric pathogen detection and nutritional indicators among controls in the Global Enteric Multicenter Study, Kenya site: an opportunity to understand reference populations in case–control studies of diarrhoea

2018 ◽  
Vol 147 ◽  
Author(s):  
D. M. Berendes ◽  
C. E. O'Reilly ◽  
S. Kim ◽  
R. Omore ◽  
J. B. Ochieng ◽  
...  
Keyword(s):  
Multicenter Study ◽  
Pathogen Detection ◽  
Reference Population ◽  
Case Control ◽  
Enteric Pathogen ◽  
Case Control Studies ◽  
Long Term Outcomes ◽  
Enteric Infections

AbstractGiven the challenges in accurately identifying unexposed controls in case–control studies of diarrhoea, we examined diarrhoea incidence, subclinical enteric infections and growth stunting within a reference population in the Global Enteric Multicenter Study, Kenya site. Within ‘control’ children (0–59 months old without diarrhoea in the 7 days before enrolment,n= 2384), we examined surveys at enrolment and 60-day follow-up, stool at enrolment and a 14-day post-enrolment memory aid for diarrhoea incidence. At enrolment, 19% of controls had ⩾1 enteric pathogen associated with moderate-to-severe diarrhoea (‘MSD pathogens’) in stool; following enrolment, many reported diarrhoea (27% in 7 days, 39% in 14 days). Controls with and without reported diarrhoea had similar carriage of MSD pathogens at enrolment; however, controls reporting diarrhoea were more likely to report visiting a health facility for diarrhoea (27%vs.7%) or fever (23%vs.16%) at follow-up than controls without diarrhoea. Odds of stunting differed by both MSD and ‘any’ (including non-MSD pathogens) enteric pathogen carriage, but not diarrhoea, suggesting control classification may warrant modification when assessing long-term outcomes. High diarrhoea incidence following enrolment and prevalent carriage of enteric pathogens have implications for sequelae associated with subclinical enteric infections and for design and interpretation of case–control studies examining diarrhoea.

Sign in / Sign up

Export Citation Format

Share Document