Su1175 PROSPECTIVE EVALUATION OF THE DIAGNOSTIC PERFORMANCE OF ENDOSCOPIC ULTRASOUND-GUIDED FINE NEEDLE BIOPSY IN ABDOMINAL SOLID LESIONS

2019 ◽  
Vol 89 (6) ◽  
pp. AB300-AB301
Author(s):  
Kunsuda Cheirsilpa ◽  
Phunchai Charatcharoenwitthaya ◽  
Wipapat V. Chalermwai ◽  
Tassanee Sriprayoon ◽  
Uayporn Kaosombatwattana ◽  
...  
2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Lachlan R. Ayres ◽  
Elizabeth K. Kmiotek ◽  
Eric Lam ◽  
Jennifer J. Telford

Background and Aims. Endoscopic ultrasound (EUS) guided fine-needle aspiration (FNA) is the method of choice for sampling pancreatic lesions. This study compares the diagnostic accuracy and safety of FNB using a novel core needle to FNA in solid pancreatic lesions. Methods. A retrospective review of patients in whom EUS FNA or FNB was performed for solid pancreatic lesions was conducted. Diagnostic performance was calculated based upon a dual classification system: classification 1, only malignant pathology considered a true positive, versus classification 2, atypical, suspicious, and malignant pathology considered a true positive. Results. 43 patients underwent FNB compared with 51 FNA. Using classification 1, sensitivity was 74.0% versus 80.0%, specificity 100% versus 100%, and diagnostic accuracy 77.0% versus 80.0% for FNB versus FNA, respectively (all p>0.05). Using classification 2, sensitivity was 97% versus 94.0%, specificity 100% versus 100%, and diagnostic accuracy 98.0% versus 94.0% for FNB versus FNA, respectively (all p>0.05). FNB required significantly fewer needle passes (median = 2) compared to FNA (median = 3; p<0.001). Adverse events occurred in two (4.5%) FNB patients compared with none in the FNA group (p>0.05). Conclusion. FNA and FNB have comparable sensitivity and diagnostic accuracy. FNB required fewer passes.


2017 ◽  
Vol 6 (8) ◽  
pp. 45
Author(s):  
Elia Armellini ◽  
Elena Trisolini ◽  
Marco Ballarè ◽  
Silvano Andorno ◽  
Corinna Pizio ◽  
...  

2019 ◽  
Vol 07 (10) ◽  
pp. E1221-E1230 ◽  
Author(s):  
Antonio Facciorusso ◽  
Valentina Del Prete ◽  
Vincenzo Rosario Buccino ◽  
Purvi Purohit ◽  
Puneet Setia ◽  
...  

Abstract Background and study aims Although newer needle designs are thought to improve diagnostic outcomes of endoscopic ultrasound-guided fine-needle biopsy, there is limited evidence on their diagnostic performance. The aim of this meta-analysis was to provide a pooled estimate of the diagnostic performance and safety profile of Franseen and Fork-tip fine-needle biopsy needles. Patients and methods Computerized bibliographic search on the main databases was performed through March 2019. The primary endpoint was sample adequacy. Secondary outcomes were diagnostic accuracy, optimal histological core procurement, mean number of needle passes, pooled specificity and sensitivity. Safety data were also analyzed. Results Twenty-four studies with 6641 patients were included and pancreas was the prevalent location of sampled lesions. Overall sample adequacy with the two newer needles was 94.8 % (93.1 % – 96.4 %), with superiority of Franseen needle over Fork-tip (96.1 % versus 92.4 %, P < 0.001). Sample adequacy in targeting pancreatic masses was 95.6% and both needles produced results superior to fine-needle aspiration (FNA) (odds ratio 4.29, 1.49 – 12.35 and 1.79, 1.01 – 3.19 with Franseen and Fork-tip needle, respectively). The rate of histological core procurement was 92.5%, whereas diagnostic accuracy and sensitivity were 95 % and 92.8 %, again with no difference between the two needles. Number of needle passes was significantly lower in comparison to FNA (mean difference: –0.42 with Franseen and –1.60 with Fork-tip needle). No significant adverse events were registered. Conclusion Our meta-analysis speaks in favor of use of newer biopsy needles as a safe and effective tool in endoscopic ultrasound-guided tissue acquisition.


Author(s):  
Akashi Fujita ◽  
Shomei Ryozawa ◽  
Yuki Tanisaka ◽  
Tomoya Ogawa ◽  
Masahiro Suzuki ◽  
...  

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