Panel Reactive Antibody Levels Are Associated With Survival in Heart Transplant Recipients Without But Not With a Ventricular Assist Device at the Time of Transplant

2015 ◽  
Vol 34 (4) ◽  
pp. S93-S94
Author(s):  
P. Chiu ◽  
J.M. Schaffer ◽  
P.E. Oyer ◽  
D. Banerjee ◽  
J. Woo ◽  
...  
2011 ◽  
Vol 142 (5) ◽  
pp. 1236-1245.e1 ◽  
Author(s):  
George J. Arnaoutakis ◽  
Timothy J. George ◽  
Arman Kilic ◽  
Eric S. Weiss ◽  
Stuart D. Russell ◽  
...  

2020 ◽  
Vol 31 (6) ◽  
pp. 874-880
Author(s):  
Felix Strangl ◽  
Anneke Ullrich ◽  
Karin Oechsle ◽  
Carsten Bokemeyer ◽  
Stefan Blankenberg ◽  
...  

Abstract Objectives Palliative care (PC) has gained rising attention in a holistic treatment approach to chronic heart failure (HF). It is unclear whether there is a need for PC in left ventricular assist device (LVAD) patients or heart transplant recipients. Methods In a cross-sectional explorative pilot study, outpatients after heart transplantation (HTx, n = 69) or LVAD implantation (n = 21) underwent screening for palliative care (PC) need and evaluation of symptom burden and psychological distress using tools that emanated from palliative cancer care. Results The ‘Palliative Care Screening Tool for Heart Failure Patients’ revealed scores of 4.3 ± 2.2 in HTx and 6.0 ± 2.1 in LVAD patients (max. 12 points, P = 0.003), indicating the need for PC (≥5 points) in 32% of HTx and 67% of LVAD patients. Symptom burden, as assessed by MIDOS (‘Minimal Documentation System for Palliative Care’) scores was substantial in both groups (4.9 ± 4.7 in HTx vs 6.6 ± 5.3 in LVAD, max. 30 points, P = 0.181). ‘Fatigue’, ‘weakness’ and ‘pain’ were the most frequent symptoms. Using the ‘Distress-Thermometer’, ‘clinically relevant’ distress was detected in 57% of HTx and 47% of LVAD patients (P = 0.445). In the PHQ-4 (‘4-Item Patient Health Questionnaire’), 45% of LVAD patients, compared to only 10% of HTx patients, reported mild symptoms of anxiety and depression. Conclusions Findings reveal substantial need for PC in LVAD patients and, to a lesser extent, in heart transplant recipients, suggesting that multi-disciplinary PC should be introduced into routine aftercare.


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