One-year follow-up optical coherence tomography after endovascular treatment with a new-generation zotarolimus-eluting stent for chronic mesenteric ischemia

The authors would present the mid-term outcomes with the use of stent-supported angioplasty in the treatment of symptomatic chronic mesenteric ischemia (CMI). The present study is a retrospective analysis of 36 patients undergoing endovascular treatment of symptomatic CMI, between November 2000 and September 2009. Primary study endpoints were defined as primary patency, periprocedural and midterm mortality and complications, and symptom improvement after intervention. Forty-one mesenteric arteries (77.3% stenotic and 22.7% occluded vessels) were treated in 36 patients with 42 stents. In 30 patients (83.3%) one visceral artery and in 6 cases (16.7%) two visceral arteries were treated. Overall mortality was 16.7% (n=6) after a 60-month follow-up (mean follow-up period 30.1 months). Two early (<30-day) deaths were caused by visceral ischemia (n=2: 5.5%). Late death was procedure-related in one patient with re-occlusion of the superior mesenteric artery after 12 months. The other 3 patients died from non procedure-related causes; e.g. twice myocardial infarction. Initial symptom relief was observed in 29 patients (80.5%); 7 patients reported no change. Primary patency was 83.3% after 5 years and secondary patency was 90.5% (38 out of 42 stents) among all patients. Two conversions to open surgery were documented. First-line endovascular approach of CMI is a reasonable strategy. Close follow-up is mandatory due to symptom recurrence and restenosis.

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P3385Difference of vascular healing after percutaneous coronary intervention between 4 kinds of new generation drug-eluting stents: an optical coherence tomography analysis

European Heart Journal ◽

10.1093/eurheartj/ehz745.0261 ◽

2019 ◽

Vol 40 (Supplement_1) ◽

Author(s):

Y Matsuhiro ◽

M Nishino ◽

H Nakamura ◽

K Yasumoto ◽

A Tanaka ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Biodegradable Polymer ◽

Neointimal Hyperplasia ◽

Drug Eluting Stents ◽

P Value ◽

Optical Coherence ◽

Durable Polymer ◽

Drug Eluting ◽

New Generation

Abstract Background New generation drug eluting stents (DES) have improved target vessel failure as compared with early generation DES and bare metal stent. Contemporary several new generation DES are different each other regarding strut thickness and drug and polymer type. A little is known about which stent induces a more favorable vascular healing at follow up. Purpose In this study, we compared the vascular healing at 8-month follow up by optical coherence tomography (OCT) between 4 different kinds of new generation DES. Methods We enrolled 112 consecutive patients (121 lesions) who underwent PCI using 4 kinds of new generation DES including biodegradable-polymer everolimus-eluting stents (BP-EES), biodegradable-polymer sirolimus-eluting stents (BP-SES), durable-polymer everolimus-eluting stents (DP-EES) and durable-polymer zotarolimus-eluting stents (DP-ZES) and who underwent 8-month follow up angiogram and OCT between July 2016 and April 2018. We compared the OCT parameters including percentage of covered struts, uncovered struts, well-apposed and uncovered struts, malapposed strut and mean neointimal hyperplasia (NIH) thickness between them. Results BP-EES consisted of 29 lesions, BP-SES consisted of 25 lesions, DP-EES consisted of 38 lesions and DP-ZES consisted of 29 lesions. A total of 734 frames with 5163 struts in BP-EES, 481 frames with 4214 struts in BP-SES, 783 frames with 6119 struts in DP-EES and 583 frames with 4708 struts in DP-ZES were analyzed. As shown in a table, mean NIH thickness was significantly higher in BP-EES and BP-SES. Thus, we compared the OCT parameters between durable-polymer (DP) group including DP-ZES and DP-EES and biodegradable-polymer (BP) group including BP-EES and BP-SES. The percentage of uncovered struts was significantly lower and mean NIH thickness was significantly higher in BP group than DP group. Results of OCT parameters BP-EES (n=29) BP-SES (n=25) DP-EES (n=38) DP-ZES (n=29) P value BP group (n=54) DP group (n=67) P value Covered struts (%) 89.5±13.6 92.4±8.6 85.5±17.5 85.0±17.7 0.29 90.9±11.6 85.3±17.4 0.08 Uncovered struts (%) 8.8±10.8 7.1±8.7 14.5±17.5 15.0±17.7 0.14 8.0±9.9 14.7±17.4 0.03 Well-apposed and uncovered struts (%) 7.9±9.9 5.9±7.7 11.7±13.1 12.3±14.0 0.15 7.0±8.9 11.9±13.4 0.04 Malapposed struts (%) 0.8±1.6 1.3±2.2 2.7±5.8 2.7±4.7 0.33 1.0±1.9 2.7±5.3 0.07 Mean NIH thickness (μm) 102±57 121±48 78±28 88±33 <0.01 111±53 82±31 <0.01 Conclusion The present OCT study demonstrated that delayed neointimal healing characterized by the presence of uncovered struts and lower mean NIH thickness was less common in BP group than DP gruop. Biodegradable-polymer may be more favorable than durable-polymer from the point of view of vascular healing.

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Analysis of the process of recovery of the foveolar region after surgery of idiopathic macular ruptures by the «temporal inverted VPM flap» method

Modern technologies in ophtalmology ◽

10.25276/2312-4911-2021-3-159-163 ◽

2021 ◽

pp. 159-163

Author(s):

S.D. Stebnev ◽

◽

V.S. Stebnev ◽

N.I. Skladchikova ◽

T.Y. Vashchenko ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Visual Acuity ◽

Retinal Thickness ◽

Outer Boundary ◽

Optical Coherence ◽

Photoreceptor Layer ◽

Corrected Distance Visual Acuity ◽

One Year ◽

Boundary Membrane

Purpose. To analyze the recovery of the foveolar region after successful surgery of idiopathic macular rupture (IMR) using the "temporal inverted VPM flap" method. Material and methods. In 33 patients (34 eyes) aged 65.2±8.1 years, operated on for stage II-IV IMR according to J. Gass (1995), in the postoperative period for up to 1 year, changes in the foveolar region were studied by optical coherence tomography (OCT). Results. Recovery of the foveolar area began from the first days after the operation and lasted for 12 months. In the period from 1 week to 1 month, the recovery and approximation to the U-shaped foveolar contour was noted in all patients. At the final follow-up period: the outer boundary membrane and the ellipsoid zone were completely restored in 26/44 (76%) and 23/34 (68%) eyes, respectively; the average central retinal thickness decreased from 396±62.6 microns to 194±66 microns (p<0.05); the corrected distance visual acuity (CDVA) increased from 0.07±0.04 to 0.35±0.21 (p<0.05). Conclusion The "temporal inverted VPM flap" method is highly effective in the surgery of idiopathic macular ruptures. The process of restoring the microstructures of the foveolar zone begins from the first days after the IMR surgery using the "temporal inverted VPM flap" method, is gradual and lasts up to one year from the start of treatment. The main stages of restoration of the microstructures of the foveolar region are: mechanical overlap of the macular rupture with HPV flaps, filling of the IMR lumen with a "glial plug", restoration of the external photoreceptor layer of the fovea. Key words: foveolar region, outer layers of the retina, idiopathic macular rupture, temporal inverted VPM flap, optical coherence tomography.

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Anterior Segment Optical Coherence Tomography Imaging of Filtering Blebs after Deep Sclerectomy with Esnoper-Clip Implant: One-year Follow-up

Current Journal of Glaucoma Practice with DVD ◽

10.5005/jp-journals-10008-1169 ◽

2014 ◽

Vol 8 (3) ◽

pp. 91-95 ◽

Cited By ~ 3

Author(s):

Teresa Gomes ◽

Maria Reina ◽

Luisa Vieira ◽

Manuel Noronha ◽

Vanessa Lemos

Keyword(s):

Optical Coherence Tomography ◽

Anterior Segment ◽

Deep Sclerectomy ◽

Optical Coherence ◽

Tomography Imaging ◽

Optical Coherence Tomography Imaging ◽

One Year

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Applying a New Automated Perimetry Pattern Based on the Stimulus Distribution of the Multifocal ERG to Improve Structure-Function Investigation in Glaucoma

Journal of Ophthalmology ◽

10.1155/2017/8780934 ◽

2017 ◽

Vol 2017 ◽

pp. 1-11 ◽

Cited By ~ 1

Author(s):

Lívia M. Brandão ◽

Matthias Monhart ◽

Andreas Schötzau ◽

Anna A. Ledolter ◽

Anja M. Palmowski-Wolfe

Keyword(s):

Optical Coherence Tomography ◽

Structure Function ◽

Automated Perimetry ◽

Optical Coherence ◽

Fiber Layer ◽

Rnfl Thickness ◽

Significant Difference ◽

Retinal Structure ◽

One Year

Purpose. To validate a new automated perimetry pattern (mf103 pattern) for the investigation of retinal structure-function relationships in glaucoma in comparison to the standard G2 pattern and to relate either field’s performance to optical coherence tomography (OCT). Methods. Automated perimetry data from the mfERG103 pattern were compared with the standard G2 pattern in glaucoma patients (18) and controls (15). The results of both (mean defect (MD) and mean sensitivity (MS)) were compared with optical coherence tomography (OCT): retinal nerve fiber layer (RNFL) thickness, macular thickness (mT), and ganglion cell analysis (GCIPL). Nine patients were followed up after one year. Results. G2 pattern and mf103 pattern did not differ significantly in MD or MS. The mf103 pattern associated significantly with more RNFL sectors in both MD and MS (p<0.01 and p<0.05, resp.). GCIPL thickness was not significantly associated with either SAP protocols. Both protocols remained comparable after one-year follow-up. Conclusions. G2 and mf103 pattern can both differentiate patients from controls with no significant difference in performance. RNFL thickness defects correlated better with mf103 than G2 with POAG. The mfERG-103 perimetry pattern can be used to establish structure-function correlations in glaucoma and may enable a more direct comparison with objective electrophysiological data.

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X-Linked Retinoschisis in Juveniles: Follow-Up by Optical Coherence Tomography

BioMed Research International ◽

10.1155/2017/1704623 ◽

2017 ◽

Vol 2017 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Qin-rui Hu ◽

Lv-zhen Huang ◽

Xiao-li Chen ◽

Hui-ka Xia ◽

Tian-qi Li ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Retinal Thickness ◽

Optical Coherence ◽

Clinical Protocol ◽

Juvenile Period ◽

Corrected Visual Acuity ◽

Structural Progression ◽

One Year ◽

Sd Oct

Purpose.To explore the structural progression of X-linked retinoschisis (XLRS) in patients by using spectral-domain optical coherence tomography (SD-OCT).Design.Retrospective, observational study.Methods.Patients who were diagnosed with XLRS by genetic testing underwent comprehensive ophthalmological examinations from December 2014 to October 2016. Each eye was measured by SD-OCT using the same clinical protocol. A correlation between best-corrected visual acuity (VA) and SD-OCT measurements was observed.Results.Six patients demonstrated retinoschisis (12 eyes) and typical foveal cyst-like cavities (10 eyes) on SD-OCT images with a mean logMAR VA of 0.48. The median age was 7.5 years at the initial visit. Their foveal retinal thickness (516.9 μm) and choroid thickness (351.4 μm) decreased at a rate of 38.1 and 7.5 μm, respectively, at the 10.5-month follow-up visit; however, there were no significant differences (P=0.622andP=0.406, resp.). There was no significant correlation between VA, the foveal retinal thickness, and subfoveal choroid thickness.Conclusions.SD-OCT images for XLRS patients during the juvenile period revealed no significant changes in the fundus structure, including the foveal retinal thickness and choroid thickness within one-year follow-up. There was a lack of correlation between VA, foveal retinal thickness, and subfoveal choroid thickness.

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