scholarly journals Dermatofibroma associated with a sweat duct skin cyst

2022 ◽  
Vol 27 ◽  
pp. 300588
Author(s):  
Jan Hrudka ◽  
Jakub Kníže ◽  
Kateřina Bodianová
Keyword(s):  
Sweat Duct

SCLEROSING SWEAT DUCT CARCINOMA IN A PERIORBITAL LOCATION

1993 ◽  
Vol 86 (Supplement) ◽  
pp. 68
Author(s):  
Eric Griener ◽  
Richard Hesse
Keyword(s):  
Sweat Duct ◽  
Duct Carcinoma ◽  
Sclerosing Sweat Duct Carcinoma

scholarly journals Decreased Filaggrin Level May Lead to Sweat Duct Obstruction in Filaggrin Mutant Mice

2017 ◽  
Vol 137 (1) ◽  
pp. 248-251 ◽  
Author(s):  
Pawinee Rerknimitr ◽  
Hideaki Tanizaki ◽  
Yasuo Yamamoto ◽  
Wataru Amano ◽  
Saeko Nakajima ◽  
...  
Keyword(s):  
Mutant Mice ◽  
Sweat Duct ◽  
Duct Obstruction

MICROCYSTIC ADNEXAL CARCINOMA (SCLEROSING SWEAT-DUCT CARCINOMA) OF THE HEAD AND NECK

1995 ◽  
Author(s):  
SN SNOW ◽  
W SAHL ◽  
R BULLEN ◽  
RS TAYLOR ◽  
R RUDNIKI ◽  
...  
Keyword(s):  
Head And Neck ◽  
Sweat Duct ◽  
Duct Carcinoma ◽  
Microcystic Adnexal Carcinoma ◽  
Sclerosing Sweat Duct Carcinoma

Bumetanide blocks CFTRG Cl in the native sweat duct

1999 ◽  
Vol 276 (1) ◽  
pp. C231-C237 ◽  
Author(s):  
M. M. Reddy ◽  
P. M. Quinton
Keyword(s):  
Basolateral Membrane ◽  
Electrical Conductance ◽  
Anion Channel ◽  
Membrane Resistance ◽  
Activation Process ◽  
Transmembrane Conductance Regulator ◽  
Sweat Duct ◽  
Transmembrane Conductance ◽  
Cystic Fibrosis Transmembrane ◽  
Human Sweat Duct

Bumetanide is well known for its ability to inhibit the nonconductive Na+-K+-2Cl−cotransporter. We were surprised in preliminary studies to find that bumetanide in the contraluminal bath also inhibited NaCl absorption in the human sweat duct, which is apparently poor in cotransporter activity. Inhibition was accompanied by a marked decrease in the transepithelial electrical conductance. Because the cystic fibrosis transmembrane conductance regulator (CFTR) Cl− channel is richly expressed in the sweat duct, we asked whether bumetanide acts by blocking this anion channel. We found that bumetanide 1) significantly increased whole cell input impedance, 2) hyperpolarized transepithelial and basolateral membrane potentials, 3) depolarized apical membrane potential, 4) increased the ratio of apical-to-basolateral membrane resistance, and 5) decreased transepithelial Cl− conductance ( G Cl). These results indicate that bumetanide inhibits CFTR G Clin both cell membranes of this epithelium. We excluded bumetanide interference with the protein kinase A phosphorylation activation process by “irreversibly” phosphorylating CFTR [by using adenosine 5′- O-(3-thiotriphosphate) in the presence of a phosphatase inhibition cocktail] before bumetanide application. We then activated CFTR G Clby adding 5 mM ATP. Bumetanide in the cytoplasmic bath (10−3 M) inhibited ∼71% of this ATP-activated CFTR G Cl, indicating possible direct inhibition of CFTR G Cl. We conclude that bumetanide inhibits CFTR G Clin apical and basolateral membranes independent of phosphorylation. The results also suggest that >10−5 M bumetanide cannot be used to specifically block the Na+-K+-2Cl−cotransporter.

Effect of Anion Transport Blockers on CFTR in the Human Sweat Duct

2002 ◽  
Vol 189 (1) ◽  
pp. 15-25 ◽  
Author(s):  
M.M. Reddy ◽  
P.M. Quinton
Keyword(s):  
Anion Transport ◽  
Sweat Duct ◽  
Human Sweat ◽  
Human Sweat Duct

Anatomoclinical study of 30 cases of sclerosing sweat duct carcinomas (microcystic adnexal carcinoma, syringomatous carcinoma and squamoid eccrine ductal carcinoma)

2015 ◽  
Vol 29 (10) ◽  
pp. 1978-1994 ◽  
Author(s):  
E. Frouin ◽  
M.D. Vignon-Pennamen ◽  
B. Balme ◽  
B. Cavelier-Balloy ◽  
U. Zimmermann ◽  
...  
Keyword(s):  
Ductal Carcinoma ◽  
Sweat Duct ◽  
Microcystic Adnexal Carcinoma
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