Clostridium paraputrificum: An atypical and rare case of septic arthritis mimicking an acute sickle cell crisis

Vascular occlusive crisis with a concurrent vision loss on both eyes is one of the most devastating disability for sickle cell disease patients. Reportedly occlusive crisis in the eyes is usually temporary whereas if not appropriately managed can result in permanent vision loss. A carefully managed sickle cell crisis could prevent multiple disabilities including blindness and stroke. We report a case of a 24-year-old female with a history of sickle cell disease who had acute bilateral vision loss during a sickle crisis and recovered significantly with a timely emergent erythrocytapheresis.

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Rare case of Ureaplasma parvum septic arthritis in an immunocompetent patient

BMJ Case Reports ◽

10.1136/bcr-2020-236396 ◽

2020 ◽

Vol 13 (9) ◽

pp. e236396

Author(s):

Abuzar Ali Asif ◽

Moni Roy ◽

Sharjeel Ahmad

Keyword(s):

Septic Arthritis ◽

Rare Case ◽

Immunocompetent Patient ◽

Next Generation ◽

Ureaplasma Parvum ◽

Urogenital Infections ◽

Joint Infections ◽

Prosthetic Joint ◽

Prosthetic Joint Infections ◽

Diagnostic Modalities

Mycoplasmatacea family comprises two genera: Mycoplasma and Ureaplasma. Ureaplasma parvum (previously known as U. urealyticum biovar 1) commonly colonises the urogenital tract in humans. Although Ureaplasma species have well-established pathogenicity in urogenital infections, its involvement in septic arthritis has been limited to prosthetic joint infections and immunocompromised individuals. We present a rare case of native right knee infection due to U. parvum identified using next-generation sequencing of microbial cell-free DNA testing and confirmed with PCR assays. This rare case of Ureaplasma septic arthritis was diagnosed using newer next-generation DNA sequencing diagnostic modalities and a literature review of prior cases, antibiotic coverage and antimicrobial resistance is incorporated as part of the discussion.

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Young child with painful edema and purpura: a case report

Italian Journal of Pediatrics ◽

10.1186/s13052-021-01001-y ◽

2021 ◽

Vol 47 (1) ◽

Author(s):

Sarah Contorno ◽

Giorgio Cozzi ◽

Irene Berti ◽

Egidio Barbi ◽

Andrea Taddio

Keyword(s):

Differential Diagnosis ◽

Child Abuse ◽

Case Report ◽

Young Child ◽

Sickle Cell ◽

Benign Condition ◽

Sickle Cell Crisis

Abstract Background We reported the case of a two-old-year boy with a painful acute hemorrhagic edema. This is a self-limited benign condition: usually, affected children are well appearing and this strongly support the diagnosis. In the opposite, in our case, we observed a painful presentation of the edema. Therefore, we demonstrated that rarely, this condition could have also a painful presentation. Conclusions This case report helps clinician to know that also acute hemorrhagic edema could have a painful presentation, so we must considered it in the differential diagnosis with sepsis, sickle cell crisis and child abuse. We believe that these findings will be of interest to pediatricians.

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