scholarly journals Nosocomial infections due to methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci at a university hospital in Taiwan from 1991 to 2003: resistance trends, antibiotic usage and in vitro activities of newer antimicrobial agents

2005 ◽  
Vol 26 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Po-Ren Hsueh ◽  
Wen-Huei Chen ◽  
Lee-Jene Teng ◽  
Kwen-Tay Luh
2004 ◽  
Vol 48 (4) ◽  
pp. 1361-1364 ◽  
Author(s):  
Po-Ren Hsueh ◽  
Lee-Jene Teng ◽  
Wen-Hwei Chen ◽  
Huei-Ju Pan ◽  
Mei-Lin Chen ◽  
...  

ABSTRACT A rapid emergence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection (from 26.3% in 1986 to 77% in 2001) was found. The susceptibility of 200 nonduplicate blood isolates of MRSA and 100 MRSA isolates causing refractory bacteremia to 22 antimicrobial agents disclosed that glycopeptides, quinupristin-dalfopristin, and linezolid remained the most active agents.


1996 ◽  
Vol 40 (10) ◽  
pp. 2416-2419 ◽  
Author(s):  
R S Schwalbe ◽  
A C McIntosh ◽  
S Qaiyumi ◽  
J A Johnson ◽  
R J Johnson ◽  
...  

The in vitro activities of LY333328 were compared with those of vancomycin, teicoplanin, and quinupristin-dalfopristin (Synercid) against 219 strains of enterococci and staphylococci, including vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus. MICs and MBCs were determined by a microtiter dilution protocol. LY333328 demonstrated superior activity against vancomycin-resistant enterococci and was the only antibiotic which was bactericidal. Its potency was comparable or superior to those of other antibiotics tested against methicillin-resistant staphylococci.


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