Structural characterization and immunomodulatory activity of a novel acid polysaccharide isolated from the pulp of Rosa laevigata Michx fruit

2020 ◽  
Vol 145 ◽  
pp. 1080-1090 ◽  
Author(s):  
Qiping Zhan ◽  
Qian Wang ◽  
Ruge Lin ◽  
Ping He ◽  
Furao Lai ◽  
...  
Keyword(s):  
Structural Characterization ◽  
Immunomodulatory Activity ◽  
Acid Polysaccharide ◽  
Rosa Laevigata

scholarly journals Physicochemical Characterization and Immunomodulatory Activity of a Novel Acid Polysaccharide from Solanum muricatum

Polymers ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 1972 ◽  
Author(s):  
Heng Yue ◽  
Qianqian Xu ◽  
Xianheng Li ◽  
Jeevithan Elango ◽  
Wenhui Wu ◽  
...  
Keyword(s):  
High Performance ◽  
Average Molecular Weight ◽  
Thermal Studies ◽  
Physicochemical Characterization ◽  
Monosaccharide Composition ◽  
Molar Ratio ◽  
Immunomodulatory Activity ◽  
Composition Analysis ◽  
Solanum Muricatum ◽  
Acid Polysaccharide

To investigate the structure and immunomodulatory activity of polysaccharide from Solanum muricatum, a novel acid polysaccharide named SMP-3a was purified from Solanum muricatum pulp through DEAE-52 cellulose column and Sephadex G-200 chromatography. Monosaccharide composition analysis showed that SMP-3a was mainly composed of rhamnose, arabinose, galactose, and galacturonic acid with the molar ratio of 1.09:2.64:1.54:1. The average molecular weight was found to be 227 kDa by high performance gel permeation chromatography (HPGPC). Thermal studies revealed the SMP-3a was a thermally stable polymer. Based on the results of methylation and NMR analysis, the backbone chain of SMP-3a was composed of →2)-α-l-Rhap-(1→, →4)-α-d-GalpA-(1→ and →4)-α-d-Galp-(1→. The side chain was consisted of α-l-Araf-(1→ and →5)-α-l-Araf-(1→. Immunomodulatory assay indicated that SMP-3a could significantly promote the proliferation of macrophages and stimulate the secretion of cytokines, including TNF-α, IL-1β, and IL-6. Our results suggested that SMP-3a could be used as a novel potential immunomodulatory agent in functional food.

Structural Characterization of a Novel Polysaccharide from Pulp Tissues of Litchi chinensis and Its Immunomodulatory Activity

2014 ◽  
Vol 62 (4) ◽  
pp. 902-911 ◽  
Author(s):  
Yongshuai Jing ◽  
Lijiao Huang ◽  
Wenjie Lv ◽  
Hui Tong ◽  
Liyan Song ◽  
...  
Keyword(s):  
Structural Characterization ◽  
Immunomodulatory Activity ◽  
Litchi Chinensis

Structural Characterization and Immunomodulatory Activity of a Polysaccharide from Eurycoma longifolia

2019 ◽  
Vol 82 (2) ◽  
pp. 169-176 ◽  
Author(s):  
Ping He ◽  
Zhou Dong ◽  
Qian Wang ◽  
Qi-Ping Zhan ◽  
Meng-Meng Zhang ◽  
...  
Keyword(s):  
Structural Characterization ◽  
Immunomodulatory Activity ◽  
Eurycoma Longifolia

Structural characterization and immunomodulatory activity of a heterogalactan from Panax ginseng flowers

2020 ◽  
pp. 109859
Author(s):  
Liangnan Cui ◽  
Lei Chen ◽  
Guang Yang ◽  
Yakun Li ◽  
Zhonghui Qiao ◽  
...  
Keyword(s):  
Panax Ginseng ◽  
Structural Characterization ◽  
Immunomodulatory Activity

Structural characterization and immunomodulatory activity of a new heteropolysaccharide from Prunella vulgaris

2015 ◽  
Vol 6 (5) ◽  
pp. 1557-1567 ◽  
Author(s):  
Chao Li ◽  
Lijun You ◽  
Xiong Fu ◽  
Qiang Huang ◽  
Shujuan Yu ◽  
...  
Keyword(s):  
Structural Characterization ◽  
Extraction Method ◽  
Hot Water ◽  
Water Extraction ◽  
Immunomodulatory Activity ◽  
Prunella Vulgaris ◽  
Hot Water Extraction

A new heteropolysaccharide, here called P1, was isolated from the fruit clusters of Prunella vulgaris using a hot water extraction method.

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