Cardiac hybrid imaging for the management of patients with known or suspected coronary artery disease

2018 ◽  
Vol 261 ◽  
pp. 236-238
Author(s):  
Daniele Andreini ◽  
Edoardo Conte ◽  
Saima Mushtaq
Author(s):  
Antti Saraste ◽  
Sharmila Dorbala ◽  
Juhani Knuuti

Cardiac hybrid imaging offers the ability to combine strengths of different imaging modalities in providing information on cardiac physiology along with cardiac and coronary anatomy. Hybrid images contain two data sets combined into a fused image in which both data sets contribute important information. Hybrid coronary computed tomography angiography and nuclear or magnetic resonance myocardial perfusion imaging has been shown to accurately detect coronary artery disease. Emerging clinical applications of cardiac hybrid imaging include evaluation of myocardial viability, cardiac or vascular inflammation, infection, and cardiac infiltration. Cardiac dedicated single photon emission computed tomography scanners, novel software methods for low count image reconstruction, and quantification of myocardial blood flow by positron emission tomography (PET) have potential to lower radiation dose associated with cardiac imaging while maintaining high diagnostic accuracy for the detection of coronary artery disease.


2011 ◽  
Vol 7 (3) ◽  
pp. 172
Author(s):  
Benoy Nalin Shah ◽  
Roxy Senior ◽  
◽  

The development of stable transpulmonary ultrasound contrast agents (UCAs) has allowed the echocardiographic assessment of myocardial perfusion, a technique known as myocardial contrast echocardiography (MCE). MCE exploits the ultrasonic properties of UCAs, which consist of acoustically active gas-filled microspheres. These are intravascular agents that have a rheology similar to red blood cells and thus allow analysis of myocardial blood flow both at rest and after stress. The combined assessment of wall motion and myocardial perfusion provides significant diagnostic and prognostic information during stress echocardiography. Functional imaging tests, such as myocardial perfusion scintigraphy and stress cardiac magnetic resonance imaging, are also used for non-invasive assessment of coronary disease. The principal advantages of MCE are that it does not expose the patient to ionising radiation or radioactive pharmaceuticals, is not contraindicated in patients with an implanted metallic device or who suffer from claustrophobia and it can be performed at the bedside. The purpose of this article is to outline the physiological principles underpinning ischaemia testing with MCE before proceeding to review the evidence base for MCE in patients with known or suspected coronary artery disease.


Author(s):  
Vasiliki Katsi ◽  
Georgios Georgiopoulos ◽  
Panagiota Mitropoulou ◽  
Konstantinos Kontoangelos ◽  
Zoi Kollia ◽  
...  

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