Annular size and interaction with trans-catheter aortic valves for treatment of severe bicuspid aortic valve stenosis: Insights from the BEAT registry

2021 ◽  
Author(s):  
Elisabetta Moscarella ◽  
Antonio Mangieri ◽  
Francesco Giannini ◽  
Didier Tchetchè ◽  
Won-Keun Kim ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Bicuspid Aortic Valve ◽  
Aortic Valve Stenosis ◽  
Aortic Valves

PM100 Systemic inflammatory activation and endothelial dysfunction predict development of aortic valve stenosis in bicuspid aortic valve

Global Heart ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e82
Author(s):  
Thanh H. Nguyen ◽  
Onn A. Ali ◽  
Matthew Chapman ◽  
Juan Mundisugih ◽  
Tamila Heresztyn ◽  
...  
Keyword(s):  
Endothelial Dysfunction ◽  
Aortic Valve ◽  
Bicuspid Aortic Valve ◽  
Aortic Valve Stenosis ◽  
Inflammatory Activation

Functional vascular alterations associated with aortic valve stenosis

2011 ◽  
Vol 152 (25) ◽  
pp. 993-999
Author(s):  
Attila Nemes ◽  
Tamás Forster
Keyword(s):  
Aortic Valve ◽  
Rheumatic Fever ◽  
Bicuspid Aortic Valve ◽  
Aortic Valve Stenosis ◽  
Predisposing Factors ◽  
Degenerative Changes ◽  
Non Invasive ◽  
Atherosclerotic Process

Degenerative changes, atherosclerotic process and calcification of valvular leaflets are mostly responsible for valvular aortic valve stenosis, but congenital bicuspid aortic valve and rheumatic fever in history are also known predisposing factors. Aortic valve stenosis is frequently associated with different functional vascular alterations. The aim of this review is to demonstrate these vascular alterations evaluated by non-invasive methods and underlying physiologic and pathophysiologic processes. Orv. Hetil., 2011, 152,993–999.

scholarly journals Aortic valve-sparing root replacement in patients with bicuspid aortic valve: long-term outcome with the David I procedure over 20 years

2020 ◽  
Vol 58 (1) ◽  
pp. 86-93 ◽  
Author(s):  
Erik Beckmann ◽  
Andreas Martens ◽  
Heike Krüger ◽  
Wilhelm Korte ◽  
Tim Kaufeld ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Bicuspid Aortic Valve ◽  
Aortic Valves ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Initial Surgery ◽  
Bicuspid Aortic Valves ◽  
Valve Sparing

Abstract OBJECTIVES Aortic valve-sparing root replacement is an excellent treatment option for patients with intact tricuspid aortic valves. However, the durability in patients with bicuspid aortic valves is still a matter of debate. The aim of this study was to analyse the short- and long-term outcomes in patients with bicuspid aortic valves. METHODS Between July 1993 and October 2015, a total of 582 patients underwent the David I procedure, 50 of whom had a bicuspid aortic valve. In these patients, the mean age was 46 ± 13 years, and 80% (n = 40) were men. Follow-up was complete for 100% of patients and comprised a total of 552 patient-years with a mean follow-up time of 11 ± 5.2 years. RESULTS In addition to the David procedure, cusp plication was performed in 34% (n = 17) of patients and commissure repair in 8% (n = 4) of patients. There were no in-hospital deaths, and 1 patient (2%) had a perioperative stroke. The 1-, 5-, 10- and 20-year survival rates of patients after discharge were 98%, 94%, 88% and 84%, respectively. The rates for freedom from valve-related reoperation at 1, 5, 10 and 20 years after initial surgery were 98%, 88%, 79% and 74%, respectively. Long-term freedom from reoperation was comparable to that of patients with tricuspid aortic valves (P = 0.2). CONCLUSIONS The David procedure has excellent short-term results in patients with a bicuspid aortic valve. In this study, the long-term durability of reimplanted bicuspid aortic valves was comparable to that of tricuspid valves. However, careful patient selection might have contributed to this, and further studies might be needed to definitely clarify this issue.

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