Direct comparison between millifluidic and bulk-mixing platform in the synthesis of amorphous drug-polysaccharide nanoparticle complex

International Journal of Pharmaceutics ◽

10.1016/j.ijpharm.2017.03.021 ◽

2017 ◽

Vol 523 (1) ◽

pp. 42-51 ◽

Author(s):

Bingxue Dong ◽

Kunn Hadinoto

Keyword(s):

Amorphous Drug ◽

Nanoparticle Complex

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Controlling the burst release of amorphous drug–polysaccharide nanoparticle complex via crosslinking of the polysaccharide chains

European Journal of Pharmaceutics and Biopharmaceutics ◽

10.1016/j.ejpb.2016.05.006 ◽

2016 ◽

Vol 104 ◽

pp. 156-163 ◽

Author(s):

Minh-Hiep Nguyen ◽

The-Thien Tran ◽

Kunn Hadinoto

Keyword(s):

Burst Release ◽

Amorphous Drug ◽

Nanoparticle Complex

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Recovery of amorphous drug-polyelectrolyte nanoparticle complex by salt-induced flocculation to circumvent the need for ultracentrifugation

Advanced Powder Technology ◽

10.1016/j.apt.2020.05.030 ◽

2020 ◽

Vol 31 (8) ◽

pp. 3102-3109

Author(s):

Bingxue Dong ◽

Wean Sin Cheow ◽

Kunn Hadinoto

Keyword(s):

Amorphous Drug ◽

Nanoparticle Complex

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Carboxymethyl cellulose is a superior polyanion to dextran sulfate in stabilizing and enhancing the solubility of amorphous drug-polyelectrolyte nanoparticle complex

International Journal of Biological Macromolecules ◽

10.1016/j.ijbiomac.2019.08.023 ◽

2019 ◽

Vol 139 ◽

pp. 500-508 ◽

Author(s):

Bingxue Dong ◽

Kunn Hadinoto

Keyword(s):

Carboxymethyl Cellulose ◽

Dextran Sulfate ◽

Amorphous Drug ◽

Nanoparticle Complex

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Millifluidic synthesis of amorphous drug-polysaccharide nanoparticle complex with tunable size intended for supersaturating drug delivery applications

European Journal of Pharmaceutics and Biopharmaceutics ◽

10.1016/j.ejpb.2016.11.030 ◽

2017 ◽

Vol 112 ◽

pp. 196-203 ◽

Author(s):

The-Thien Tran ◽

Minh-Hiep Nguyen ◽

Yong Zen Tan ◽

Jia Wei Chew ◽

Saif A. Khan ◽

...

Keyword(s):

Drug Delivery ◽

Drug Delivery Applications ◽

Amorphous Drug ◽

Nanoparticle Complex

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Amorphous drug nanoparticle complex as bioavailability enhancement strategy of poorly soluble drugs

Proceedings of the 4th World Congress on Recent Advances in Nanotechnology ◽

10.11159/nddte19.3 ◽

2019 ◽

Author(s):

Kunn Hadinoto Ong

Keyword(s):

Poorly Soluble Drugs ◽

Bioavailability Enhancement ◽

Poorly Soluble ◽

Amorphous Drug ◽

Nanoparticle Complex

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Enhancing the stability of amorphous drug-polyelectrolyte nanoparticle complex using a secondary small-molecule drug as the stabilizer: A case study of ibuprofen-stabilized curcumin-chitosan nanoplex

International Journal of Pharmaceutics ◽

10.1016/j.ijpharm.2019.119007 ◽

2020 ◽

Vol 575 ◽

pp. 119007

Author(s):

Li Ming Lim ◽

Kunn Hadinoto

Keyword(s):

Small Molecule ◽

Small Molecule Drug ◽

The Stability ◽

Amorphous Drug ◽

Nanoparticle Complex

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Enhancing the physical stability and supersaturation generation of amorphous drug-polyelectrolyte nanoparticle complex via incorporation of crystallization inhibitor at the nanoparticle formation step: A case of HPMC versus PVP

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2019.105035 ◽

2019 ◽

Vol 138 ◽

pp. 105035 ◽

Author(s):

Bingxue Dong ◽

Li Ming Lim ◽

Kunn Hadinoto

Keyword(s):

Physical Stability ◽

Nanoparticle Formation ◽

Crystallization Inhibitor ◽

Amorphous Drug ◽

Formation Step ◽

Nanoparticle Complex

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Self-assembled amorphous drug–polyelectrolyte nanoparticle complex with enhanced dissolution rate and saturation solubility

Journal of Colloid and Interface Science ◽

10.1016/j.jcis.2011.10.011 ◽

2012 ◽

Vol 367 (1) ◽

pp. 518-526 ◽

Author(s):

Wean Sin Cheow ◽

Kunn Hadinoto

Keyword(s):

Dissolution Rate ◽

Saturation Solubility ◽

Enhanced Dissolution ◽

Self Assembled ◽

Amorphous Drug ◽

Nanoparticle Complex

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Preserving the supersaturation generation capability of amorphous drug-polysaccharide nanoparticle complex after freeze drying

International Journal of Pharmaceutics ◽

10.1016/j.ijpharm.2015.02.057 ◽

2015 ◽

Vol 484 (1-2) ◽

pp. 115-123 ◽

Author(s):

Tie Yi Kiew ◽

Wean Sin Cheow ◽

Kunn Hadinoto

Keyword(s):

Freeze Drying ◽

Amorphous Drug ◽

Nanoparticle Complex

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Amorphous drug-polyelectrolyte nanoparticle complex with controlled release functionality, enhanced amorphous stability, and its continuous production platform

10.32657/10356/138167 ◽

2019 ◽

Author(s):

◽

Bingxue Dong

Keyword(s):

Controlled Release ◽

Continuous Production ◽

Production Platform ◽

Amorphous Drug ◽

Nanoparticle Complex

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