scholarly journals Corrigendum to “Identification of critical formulation parameters affecting the in vitro release, permeation, and rheological properties of the acyclovir topical cream” [Int. J. Pharm. 590 (2020) 119914]

2021 ◽  
pp. 120787
Author(s):  
Nahid S. Kamal ◽  
Yellela S.R. Krishnaiah ◽  
Xiaoming Xu ◽  
Ahmed S. Zidan ◽  
Sam G. Raney ◽  
...  
Keyword(s):  
Rheological Properties ◽  
In Vitro Release ◽  
Topical Cream ◽  
Formulation Parameters ◽  
Vitro Release

Identification of critical formulation parameters affecting the in vitro release, permeation, and rheological properties of the acyclovir topical cream

2020 ◽  
Vol 590 ◽  
pp. 119914
Author(s):  
Nahid S. Kamal ◽  
Yellela S.R. Krishnaiah ◽  
Xiaoming Xu ◽  
Ahmed S. Zidan ◽  
Sameersingh Raney ◽  
...  
Keyword(s):  
Rheological Properties ◽  
In Vitro Release ◽  
Topical Cream ◽  
Formulation Parameters ◽  
Vitro Release

Impact of Formulation Parameters on In Vitro Release from Long-Acting Injectable Suspensions

2021 ◽  
Vol 23 (2) ◽  
Author(s):  
Quanying Bao ◽  
Yuan Zou ◽  
Yan Wang ◽  
Stephanie Choi ◽  
Diane J. Burgess
Keyword(s):  
In Vitro Release ◽  
Formulation Parameters ◽  
Long Acting ◽  
Vitro Release

Formulation and Evaluation of Teneligliptine Pellet

2019 ◽  
Vol 9 (01) ◽  
pp. 51-57
Author(s):  
Bodhle Priyanka Raju ◽  
Satish V Shirolkar
Keyword(s):  
Chemical Interaction ◽  
In Vitro Release ◽  
Angle Of Repose ◽  
Dependent Manner ◽  
32 Factorial Design ◽  
Formulation Parameters ◽  
Tapped Density ◽  
Vitro Release ◽  
Pellet Formulation

The present study is an attempt to formulate and evaluate Teneligliptin hydrobromide hydrate pellets. Teneligliptin is a potent, selective DPP-4 inhibitor, which is believed to exert its actions in diabetes mellitus patients. Teneligliptin increases insulin release and decreases glucagon levels in the circulation in a glucose dependent manner. The Teneligliptin pellets were prepared by using blend of MCC, Lactose, Crospovidone and PVP K-30. Pellet formulation was optimized for formulation parameters (concentration of Crosspovidone and PVP K-30) using 32 factorial design. FTIR studies showed absence of chemical interaction between the drug and polymer. The pellets were prepared and evaluated in terms of bulk density, tapped density, angle of repose and in-vitro release study. In-vitro release of drug was compared with in-vitro release of drug from marketed formulation (Dynaglipt Tablet).

Relationship between rheological properties, in vitro release and in vivo equivalency of topical formulations of diclofenac

2019 ◽  
Vol 572 ◽  
pp. 118755 ◽  
Author(s):  
María Pleguezuelos-Villa ◽  
Matilde Merino-Sanjuán ◽  
Mª Jesús Hernández ◽  
Amparo Nácher ◽  
Daniel Peris ◽  
...  
Keyword(s):  
Rheological Properties ◽  
In Vitro Release ◽  
Topical Formulations ◽  
Vitro Release

Study on in vitro release patterns of fentanyl-loaded PLGA microspheres

2003 ◽  
Vol 20 (5) ◽  
pp. 569-579 ◽  
Author(s):  
S.-A. Seo ◽  
G. Khang ◽  
J. M. Rhee ◽  
J. Kim ◽  
H. B. Lee
Keyword(s):  
In Vitro Release ◽  
Plga Microspheres ◽  
Vitro Release

Reliability of a Single β-Thromboglobulin Measurement in a Diabetic Population : Importance of PGE1 in Anticoagulant Mixture

1987 ◽  
Vol 57 (02) ◽  
pp. 201-204 ◽  
Author(s):  
P Y Scarabin ◽  
L Strain ◽  
C A Ludlam ◽  
J Jones ◽  
E M Kohner
Keyword(s):  
In Vitro Release ◽  
Mean Value ◽  
Reliable Estimate ◽  
Diabetic Patients ◽  
Single Measurement ◽  
Diabetic Population ◽  
The Difference ◽  
Vitro Release

SummaryDuring the collection of samples for plasma β-thromboglobulin (β-TG) determination, it is well established that artificially high values can be observed due to in-vitro release. To estimate the reliability of a single β-TG measurement, blood samples were collected simultaneously from both arms on two separate occasions in 56 diabetic patients selected for a clinical trial. From each arm, blood was taken into two tubes containing an anticoagulant mixture with (tube A) and without (tube B) PGE!. The overall mean value of B-TG in tube B was 1.14 times higher than in tube A (p <0.01). The markedly large between-arms variation accounted for the most part of within-subject variation in both tubes and was significantly greater in tube B than in tube A. Based on the difference between B-TG values from both arms, the number of subjects with artifically high B-TG values was significantly higher in tube B than in tube A on each occasion (overall rate: 28% and 14% respectively). Estimate of between-occasions variation showed that B-TG levels were relatively stable for each subject between two occasions in each tube. It is concluded that the use of PGEi decreases falsely high B-TG levels, but a single measurement of B-TG does not provide a reliable estimate of the true B-TG value in vivo.

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