Racial Disparities in Treatment Outcomes for African American Women with Ductal Carcinoma In Situ Receiving Whole Breast Irradiation following Breast Conserving Surgery

2010 ◽  
Vol 78 (3) ◽  
pp. S222
Author(s):  
C. Nelson ◽  
S. Goyal ◽  
M. Moran ◽  
S. Motwani ◽  
B. Haffty
Keyword(s):  
African American ◽  
Racial Disparities ◽  
African American Women ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Breast Conserving Surgery ◽  
Whole Breast Irradiation ◽  
Breast Irradiation

scholarly journals Society of Surgical Oncology–American Society for Radiation Oncology–American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma In Situ

2016 ◽  
Vol 34 (33) ◽  
pp. 4040-4046 ◽  
Author(s):  
Monica Morrow ◽  
Kimberly J. Van Zee ◽  
Lawrence J. Solin ◽  
Nehmat Houssami ◽  
Mariana Chavez-MacGregor ◽  
...  
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Ipsilateral Breast Tumor Recurrence ◽  
Breast Conserving Surgery ◽  
Whole Breast Irradiation ◽  
Breast Irradiation ◽  
Margin Width ◽  
American Society

Background Controversy exists regarding the optimal negative margin width for ductal carcinoma in situ (DCIS) treated with breast-conserving surgery and whole-breast irradiation (WBRT). Methods A multidisciplinary consensus panel used a meta-analysis of margin width and ipsilateral breast tumor recurrence (IBTR) from a systematic review of 20 studies including 7883 patients and other published literature as the evidence base for consensus. Results Negative margins halve the risk of IBTR compared with positive margins defined as ink on DCIS. A 2 mm margin minimizes the risk of IBTR compared with smaller negative margins. More widely clear margins do not significantly decrease IBTR compared with 2 mm margins. Negative margins less than 2 mm alone are not an indication for mastectomy, and factors known to impact rates of IBTR should be considered in determining the need for re-excision. Conclusion The use of a 2 mm margin as the standard for an adequate margin in DCIS treated with WBRT is associated with low rates of IBTR and has the potential to decrease re-excision rates, improve cosmetic outcome, and decrease health care costs. Clinical judgment should be used in determining the need for further surgery in patients with negative margins < 2 mm.

Ductal carcinoma in situ treated with breast-conserving surgery and accelerated partial breast irradiation

Cancer ◽  
2010 ◽  
Vol 117 (6) ◽  
pp. 1149-1155 ◽  
Author(s):  
Sharad Goyal ◽  
Frank Vicini ◽  
Peter D. Beitsch ◽  
Henry Kuerer ◽  
Martin Keisch ◽  
...  
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Breast Conserving Surgery ◽  
Accelerated Partial Breast Irradiation ◽  
Partial Breast Irradiation ◽  
Breast Irradiation
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