Redefinition of Liroetis, with descriptions of two new species and an annotated list of species (Coleoptera: Chrysomelidae: Galerucinae)

The genus Liroetis Weise, 1889 is redefi ned. The following new synonymies are established: Liroetis Weise, 1889 = Siemssenius Weise, 1922, syn. nov. = Pseudoliroetis Laboissière, 1929, syn. nov. = Zangia Chen, 1976, syn. nov. Consequently, the following new combinations are proposed: Liroetis coeruleus (Jiang, 1990) comb. nov.; Liroetis latispinus (Chen, 1976) comb. nov.; Liroetis nigricollis (Jiang, 1990) comb. nov.; Liroetis pallidulus (Jiang, 1990) comb. nov. (all from Zangia); Liroetis nigropictus (Fairmaire, 1889) comb. nov. (from Leptarthra); Liroetis cheni (Lee, 2016) comb. nov.; Liroetis elongatus (Kimoto, 1977) comb. nov.; Liroetis jeanvoinei (Laboissière, 1929) comb. nov.; Liroetis jungchani (Lee, 2016) comb. nov.; Liroetis liui (Lee, 2016) comb. nov.; Liroetis metallipennis (Chûjô, 1962) comb. nov.; Liroetis modestus (Weise, 1922) comb. nov.; Liroetis nigriceps (Laboissière, 1929) comb. nov.; Liroetis rufi pennis (Chûjô, 1962) comb. nov.; Liroetis sulcipennis (Zhang & Yang, 2008) comb. nov.; Liroetis tsoui (Lee, 2016) comb. nov.; and Liroetis yuae (Lee, 2016) comb. nov. (all from Siemssenius). Two new species, Liroetis aurantiacus sp. nov., from continental South East Asia, and L. baolocanus sp. nov., from Vietnam, are described. A new substitute name, Liroetis medvedevi nom. nov., is proposed for L. nigricollis Medvedev, 2009 preoccupied by L. nigricollis (Jiang, 1990). The following new synonyms are established: Liroetis aeneipennis Weise, 1889 = L. tiemushannis Jiang, 1988, syn. nov.; Liroetis ephippiatus Laboissière, 1930 = Zangia signata Jiang, 1990, syn. nov. = L. postmaculatus Lopatin, 2004, syn. nov.; Liroetis leechi Jacoby, 1890 = L. verticalis Jiang, 1988, syn. nov.; Liroetis nigricollis (Jiang, 1990) = L. unicolor Zhang, Li & Yang, 2008, syn. nov.; Liroetis reitteri (Pic, 1934) = Pseudoliroetis trifasciata Jiang, 1992, syn. nov. The spelling of Liroetis tiemushannis Jiang, 1988 is fixed using the First Reviewer Principle. Species of Liroetis are divided into five species-groups based on the combination of the following characters: presence/absence of border on anterior pronotal margin, width/length ratio of pronotum, structure of aedeagus, presence/absence of metatibial spur. The established groups are: the aeneipennis group, the aurantiacus group, the flavipennis group, the fulvipennis group, and the grandis group. The gender of Liroetis is masculine.

Prognostic Impact of Surgical Margin in Hepatectomy On Patients with Hepatocellular Carcinoma: A Meta-Analysis of Observational Studies

Objective This study aims to comprehensively evaluate the prognostic impact of the surgical margin in hepatectomy on patients diagnosed with hepatocellular carcinoma (HCC). Methods A comprehensive and systematic search for eligible articles published in English before July 2021 was conducted in PubMed, Cochrane Library, Web of Science, and Embase electronic databases. Notably, overall survival (OS) and disease-free survival (DFS) were the primary endpoints. Results In total, 37 observational studies with 12,295 cases were included in this meta-analysis. The results revealed that a wide surgical margin (≥1 cm) was associated with better OS (hazard ration (HR), 0.70; 95% confidence interval (CI), 0.63-0.77) and DFS (HR, 0.66; 95% CI, 0.61-0.71) compared to a narrow surgical margin (<1 cm). Subgroup analyses were conducted based on median follow-up time, gender, country, hepatitis B surface antigen (HBsAg) status, tumor number, and liver cirrhosis. The prognostic benefit of a wide surgical margin was consistent in most subgroups, however, analysis of studies from Western countries showed that margin width was not associated with prognosis. Conclusion In summary, a wide surgical margin prolongs the long-term prognosis of HCC patients compared to a narrow surgical margin.

Technical Aspects And Early Results of Uniportal Video-Assisted Thoracoscopic Complex Segmentectomy: A 30 Case-Series Study

Background. With the advantages of better cosmetic incision and faster recovery, uniportal video-assisted thoracoscopic surgery (UP-VATS) has developed rapidly worldwide in recent decades and indications for UP-VATS were further expanded as those for conventional VATS. Complex segmentectomy that makes several, or intricate intersegmental planes, with more a complex procedure, continues to be a difficulty in minimally invasive techniques. However, there are few reports as yet on UP-VATS complex segmentectomy. In this report, we describe the perioperative clinical data and operative techniques and present our early results of UP-VATS complex segmentectomy in our hospital. Methods. The records of a total of 30 patients who underwent UP-VATS complex segmentectomy by a single surgeon between January 2021 and June 2021 were retrospectively reviewed. We defined cases as complex segmentectomy if they required resection of segment 9, 10, combined segmentectomy, segmentectomy+subsegmentectomy, subsegmentectomy, or combined subsegmentectomy. Results. The mean age was 52.8±9.9 years old; mean nodule size was 0.84±0.36 cm; the mean margin width was 2.307±0.309 cm; median operative time was 229.0±58.06 minutes; mean operative hemorrhage was 56.60±17.95 mL; 5.58±1.74 lymph nodes dissected had not metastasized; mean duration of postoperative chest tube drainage was 4.7±1.4 days; and mean postoperative hospital stay was 6.5±3.0 days. Although 1 patient experienced a prolonged air leak, the other 29 recovered uneventfully. Another patient failed to reach the 2cm safe margins who received completion lobectomy later. Conclusions. UP-VATS complex segmentectomy is a safe and effective procedure in the treatment of lung cancers, sparing more pulmonary parenchyma and ensuring safe margins, the disadvantage being lengthy operative times during early acquisition of skills.

1330 How Does the Tumour-Free Margin Width After Breast-Conserving Surgery in Patients with Ductal Carcinoma in Situ (DCIS) Impact Local Recurrence Rates?

Introduction In the UK, breast conserving surgery (BCS) has been indicated to completely excise ductal carcinoma in situ(DCIS) to negative margins for around 70% of diagnosed women. The tumour-free radial surgical margin width is an important marker for determining the local recurrence (LR). Setting the margin too wide will result in additional re-excision and too low may result in increased LR rates. This review investigates the different tumour-free margins and its effect on LR. Method A literature review was conducted using the Cochrane library and Pubmed database with key terms. Cohort studies of more than 100 participants with a five-year follow up in women over 18 were included. Results &gt;2mm versus 0mm: LR was significantly reduced in DCIS from one very-low evidence retrospective cohort studies (N = 1,503). &gt;2mm versus 1-2mm: Meaningful reduction in LR with DCIS was found in one very low-quality retrospective cohort study(N = 433). &gt;2mm versus &lt;1mm: Clinically meaningful reduction in LR for DCIS was found in very low-quality retrospective study (N = 466). &gt;2mm versus 1-2mm: Meaningful reduction in LR with DCIS was found in one very low-quality retrospective cohort study(N = 433). Conclusions LR rates were reduced by further increasing the negative margin width in DCIS but only low-quality evidence was available to define these margins. This is an area for further research to enhance patient care and prevent increased LR.

BREAST-CONSERVING SURGERY AFTER NEOADJUVANT CHEMOTHERAPY IN BREAST CANCER PATIENTS

The purpose of the study was to present the most recent data on the outcomes of breast-conserving surgery after neoadjuvant chemotherapy for breast cancer patients.Material and methods. We analyzed relevant publications available in the pubmed, cochrane library, e-library databases between 1990 and 2020, and 24 of them were used to write this review.Results. Neoadjuvant chemotherapy for breast cancer patients is currently a widespread treatment option. The main advantage of this type of treatment for patients with early stage breast cancer is the feasibility of performing breast-conserving surgery in cases of partial or complete clinical response and, therefore, the improvement of the quality of life of patients with equivalent rates of disease-free survival compared to radical mastectomies.Conclusion. Numerous studies have shown that breast-conserving surgery following neoadjuvant chemotherapy is the safe surgery with good oncologic outcomes and an alternative to radical mastectomies in breast cancer patients. However, further studies are required to determine the optimal safe resection margin width in patients with complete and partial responses to neoadjuvant chemotherapy.

Agri-environment schemes do not support Brown Hare populations due to inadequate scheme application

The goal of many agri-environment schemes (AES) is to increase biodiversity in agroecosystems. AES effects are often measured on invertebrates and birds; mammals as indicator species are infrequently targets of such researches. Our goal was to evaluate the local-scale effects of the Hungarian Agri-Environmental Measures (AEM) on the European brown hare (Lepus europaeus), which shows decreasing population trends across Europe. We compared hare abundances and their dropping numbers in AEM and control agricultural arable and grassland fields of 17 game management units in two seasons. We also examined the quality of arable fields based on their margin width and vegetation cover. We found that margin quality was higher in AEM than in the control fields. Control grasslands had higher vegetation quality than the AEM grasslands. We found a significant difference in hare counts between AEM and control arable fields in spring but no difference in autumn. The dropping densities did not differ in any season, treatment category or agroecosystem type. We conclude that the AEM program (2009-2014) in Hungary was not effective for the hare, and this might have been caused by the inadequate or weak application of AEM practices. We provide recommendations for future AEM programs to enhance biodiversity.

Rheological inheritance controls the formation of segmented rifted margins in cratonic lithosphere

Observations from rifted margins reveal that significant structural and crustal variability develops through the process of continental extension and breakup. While a clear link exists between distinct margin structural domains and specific phases of rifting, the origin of strong segmentation along the length of margins remains relatively ambiguous and may reflect multiple competing factors. Given that rifting frequently initiates on heterogenous basements with a complex tectonic history, the role of structural inheritance and shear zone reactivation is frequently examined. However, the link between large-scale variations in lithospheric structure and rheology and 3-D rifted margin geometries remains relatively unconstrained. Here, we use 3-D thermo-mechanical simulations of continental rifting, constrained by observations from the Labrador Sea, to unravel the effects of inherited variable lithospheric properties on margin segmentation. The modelling results demonstrate that variations in the initial crustal and lithospheric thickness, composition, and rheology produce sharp gradients in rifted margin width, the timing of breakup and its magmatic budget, leading to strong margin segmentation.

Impact of surgical margin width on long-term outcomes for intrahepatic cholangiocarcinoma: a multicenter study

Background The objective of this study was to investigate the survival outcomes of surgical margin width in intrahepatic cholangiocarcinoma (ICC). Methods Between November 2011 and August 2017, patients who underwent hepatectomy for ICC were collected from 13 major hepatopancreatobiliary centers in China. The survival outcomes for patients who underwent wide margin hepatectomy (WMH) were compared with those who underwent narrow margin hepatectomy (NMH) using the 1:1 propensity score matching (PSM). Results Among 478 included patients, 195 (40.8%) underwent WMH whereas 283 (59.2%) underwent NMH. PSM yielded 79 matched patients with similar baseline characteristics. Patients underwent WMH had a significant better OS and DFS compared with those underwent NMH (before PSM: median OS 27 vs 17 months, P < 0.05; median DFS 15 vs 8 months, P = 0.001, after PSM: median OS 41 vs 22 months, p < 0.05; median DFS 16 vs 10 months, p < 0.05). However, subgroup analysis based on the AJCC staging system, WMH could only improve the survival outcomes in AJCC I ICC patients (Stage I: OS, DFS, P<0.05). Conclusions Surgeons should strive to achieve a wide surgical margin for patients with AJCC I ICC to optimize the long-term outcome.