Radiation Therapy for Extracranial Hemangiopericytoma/Solitary Fibrous Tumor: A Study From the Rare Cancer Network

2016 ◽  
Vol 96 (2) ◽  
pp. E707 ◽  
Author(s):  
M. Krengli ◽  
B. De Bari ◽  
S. Villa ◽  
J.H.A.M. Kaanders ◽  
S. Torrente ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Solitary Fibrous Tumor ◽  
Rare Cancer ◽  
Fibrous Tumor ◽  
Cancer Network

Radiotherapy in the treatment of extracranial hemangiopericytoma/solitary fibrous tumor: Study from the Rare Cancer Network

2020 ◽  
Vol 144 ◽  
pp. 114-120 ◽  
Author(s):  
Marco Krengli ◽  
Tiziana Cena ◽  
Thomas Zilli ◽  
Barbara A. Jereczek-Fossa ◽  
Berardino De Bari ◽  
...  
Keyword(s):  
Solitary Fibrous Tumor ◽  
Rare Cancer ◽  
Tumor Study ◽  
Fibrous Tumor ◽  
Cancer Network

scholarly journals Radiotherapy for marginally resected, unresectable or recurrent giant cell tumor of the bone: a rare cancer network study

Rare Tumors ◽  
2011 ◽  
Vol 3 (4) ◽  
pp. 150-152 ◽  
Author(s):  
Sumita Bhatia ◽  
Leszek Miszczyk ◽  
Martine Roelandts ◽  
Tan Dat Nguyen ◽  
Tom Boterberg ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Giant Cell ◽  
Local Control ◽  
Symptom Relief ◽  
Significant Proportion ◽  
Rare Cancer ◽  
Giant Cell Tumors ◽  
Number Of Patients ◽  
Cancer Network

The role of radiotherapy for local control of marginally resected, unresectable, and recurrent giant cell tumors of bone (GCToB) has not been well defined. The number of patients affected by this rare disease is low. We present a series of 58 patients with biopsy proven GCToB who were treated with radiation therapy. A retrospective review of the role of radiotherapy in the treatment of GCToB was conducted in participating institutions of the Rare Cancer Network. Eligibility criteria consisted of the use of radiotherapy for marginally resected, unresectable, and recurrent GCToB. Fifty-eight patients with biopsy proven GCToB were analyzed from 9 participating North American and European institutions. Forty-five patients had a primary tumor and 13 patients had a recurrent tumor. Median radiation dose was 50 Gy in a median of 25 fractions. Indication for radiation therapy was marginal resection in 33 patients, unresectable tumor in 13 patients, recurrence in 9 patients and palliation in 2 patients. Median tumor size was 7.0 cm. A significant proportion of the tumors involved critical structures. Median follow-up was 8.0 years. Five year local control was 85%. Of the 7 local failures, 3 were treated successfully with salvage surgery. All patients who received palliation achieved symptom relief. Five year overall survival was 94%. None of the patients experienced grade 3 or higher acute toxicity. This study reports a large published experience in the treatment of GCToB with radiotherapy. Radiotherapy can provide excellent local control for incompletely resected, unresectable or recurrent GCToB with acceptable morbidity.

Radiation Therapy in Intrathoracic Sarcomas: A Rare Cancer Network Study

2018 ◽  
Vol 102 (3) ◽  
pp. e295-e296
Author(s):  
F. Larsen ◽  
P. Sargos ◽  
V. Linacre ◽  
F. Suarez ◽  
M. Terlizzi ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Rare Cancer ◽  
Cancer Network

Paraganglioma of the head and neck region, treated with radiation therapy, a Rare Cancer Network study

Head & Neck ◽  
2019 ◽  
Vol 41 (6) ◽  
pp. 1770-1776 ◽  
Author(s):  
Yasmin Lassen‐Ramshad ◽  
Enis Ozyar ◽  
Senem Alanyali ◽  
Philip Poortmans ◽  
Paul Houtte ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Head And Neck ◽  
Neck Region ◽  
Rare Cancer ◽  
Head And Neck Region ◽  
Cancer Network

scholarly journals A rare case of solitary fibrous tumor of the liver and highly differentiated rectal adenocarcinoma

2021 ◽  
Vol 8 (4) ◽  
pp. 87-95
Author(s):  
S. A. Shinkarev ◽  
M. N. Lando ◽  
V. N. Brykin ◽  
R. V. Zhinkin ◽  
O. E. Pestryakov ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Solitary Fibrous Tumor ◽  
Rectal Adenocarcinoma ◽  
Villous Tumor ◽  
Malignant Neoplasms ◽  
Anatomical Location ◽  
Depth Of Invasion ◽  
Solitary Fibrous Tumors ◽  
Dynamic Observation ◽  
Fibrous Tumor

Solitary fibrous tumors (SFT) are rare spindle cell mesenchymal neoplasms of presumably fibroblastic origin with undefined malignancy potential and rare metastasis. Their most frequent localization is in the pleura, where they have been first described. The incidence of solitary fibrous tumors localized in liver is extremely low. The clinical picture of SFT is nonspecific and is not due to the anatomical location of the tumor and it's size.In the majority of cases these tumors are benign. However, a number of them still may have signs of malignancy: an aggressive course with possible local recurrence and distant metastasis. The main method of treatment of hepatic solitary fibrous tumor (as well as SFT of other localization) with it's resectability is surgery. Radical removal of the tumor in the majority of cases leads to recovery. Subsequently, the operated patients should be subjected to strict dynamic observation with regularity as in malignant neoplasms (MN).The importance for chemotherapy and radiation therapy in the treatment of hepatic solitary fibrous tumor has not been determined in clinical guidelines to date.There are isolated reports of the use of chemotherapy or radiation therapy for the treatment of cases when tumor resection is not radical or there are signs of malignant neoplasm.In literature, there are numerous reports of a combination of a solitary fibrous tumor of any localization with malignant neoplasms of other organs in the same patients.In this report, we represent a clinical case of a 64-year-old woman, who had a solitary fibrous tumor of the liver and highly differentiated rectal adenocarcinoma. The patient underwent resection of the first segment of the left lobe of the liver. After a month and a half, transanal excision of the villous tumor of the rectum. The pathologic and immunohistochemical examination of the liver tumor revealed a malignant solitary fibrous tumor. After researching villous tumor of the rectum - a highly differentiated adenocarcinoma with a depth of invasion of the submucous layer of the intestinal wall up to 1/3 (T1sm1 according to Kikuchi). During dynamic observation for twenty-five months after the operation, the patient has no signs of tumor recurrence and metastasis.

scholarly journals Single Solitary Fibrous Tumor Brain Metastasis in a Patient with Simultaneous Adenocarcinoma of the Lung: Case Report and Review of the Literature

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Erin A. Kaya ◽  
Jonathan D. Carlson ◽  
Cheddhi J. Thomas ◽  
Aaron E. Wagner ◽  
Robert K. Fairbanks ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Solitary Fibrous Tumor ◽  
Local Treatment ◽  
Clinical Situation ◽  
The Body ◽  
Postoperative Radiation Therapy ◽  
Adenocarcinoma Of The Lung ◽  
Mesenchymal Neoplasm ◽  
Fibrous Tumor ◽  
The Brain

We present a unique case of a patient simultaneously diagnosed with solitary fibrous tumor (SFT) and unrelated adenocarcinoma of the lung, both proven with separate pathology. It was subsequently found that the SFT had metastasized to the brain by additional pathology, and not the predicted adenocarcinoma. SFTs are a rare mesenchymal neoplasm that accounts for less than 2% of all reported soft tissue tumors. SFTs most commonly arise in the thoracic cavity, but are frequently found in various locations throughout the body, and rarely metastasize to the brain. This case highlights that rare neoplasms, such as SFT, should not be ruled out as a potential cause of metastasis. Due to the rarity of this clinical situation, we also provide a review and discussion of previously reported SFT cases and the use of postoperative radiation therapy. The optimal treatment for individual patients remains unclear in this unique situation. Surgical resection followed by adjuvant Gamma Knife radiation therapy to the surgical bed appears to be a safe option for local treatment of SFT in select patients. Further studies are needed of this rare clinical situation in order to better understand and optimize future treatments for patients with SFT and metastasis to the brain.

Radiation Therapy in Extracranial Chondrosarcomas: A Multicenter French Sarcoma Group and Rare Cancer Network Study

2018 ◽  
Vol 102 (3) ◽  
pp. e369-e370
Author(s):  
M. Terlizzi ◽  
E. Rapeaud ◽  
C. Le Pechoux ◽  
S. Salas ◽  
D. Lerouge ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Rare Cancer ◽  
Cancer Network
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