scholarly journals Evaluating Intensity Modulated Proton Therapy Relative to Passive Scattering Proton Therapy for Increased Vertebral Column Sparing in Craniospinal Irradiation in Growing Pediatric Patients

2017 ◽  
Vol 98 (1) ◽  
pp. 37-46 ◽  
Author(s):  
Drosoula Giantsoudi ◽  
Joao Seco ◽  
Bree R. Eaton ◽  
F. Joseph Simeone ◽  
Hanne Kooy ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Vertebral Column ◽  
Pediatric Patients ◽  
Craniospinal Irradiation ◽  
Intensity Modulated Proton Therapy ◽  
Intensity Modulated ◽  
Passive Scattering

SU-E-T-369: Evaluating Intensity Modulated Proton Therapy Relative to Passive Scattering Proton Therapy for Increased Vertebral Column Sparing in CSI of Pediatric Patients

2015 ◽  
Vol 42 (6Part17) ◽  
pp. 3418-3418
Author(s):  
J Seco ◽  
D Giantsoudi ◽  
BR Eaton ◽  
JA Adams ◽  
H Paganetti ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Vertebral Column ◽  
Pediatric Patients ◽  
Intensity Modulated Proton Therapy ◽  
Intensity Modulated ◽  
Passive Scattering

SU-E-T-340: Use of Intensity Modulated Proton Therapy (IMPT) for Reducing the Dose to Cochlea in Craniospinal Irradiation (CSI) of Pediatric Patients

2014 ◽  
Vol 41 (6Part16) ◽  
pp. 302-302
Author(s):  
J Dormer ◽  
A Kassaee ◽  
H Lin ◽  
X Ding ◽  
R Lustig
Keyword(s):  
Proton Therapy ◽  
Pediatric Patients ◽  
Craniospinal Irradiation ◽  
Intensity Modulated Proton Therapy ◽  
Intensity Modulated

SU-E-T-417: Experimental Verification of Robustness Optimized Intensity Modulated Proton Therapy Plans for Craniospinal Irradiation

2015 ◽  
Vol 42 (6Part18) ◽  
pp. 3429-3430
Author(s):  
J Yu ◽  
L Liao ◽  
N Sahoo ◽  
X Zhu ◽  
M Gillin ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Experimental Verification ◽  
Craniospinal Irradiation ◽  
Intensity Modulated Proton Therapy ◽  
Intensity Modulated

TH-C-BRD-12: Robust Intensity Modulated Proton Therapy Plan Can Eliminate Junction Shifts for Craniospinal Irradiation

2014 ◽  
Vol 41 (6Part32) ◽  
pp. 553-553 ◽  
Author(s):  
L Liao ◽  
S Jiang ◽  
Y Li ◽  
X Wang ◽  
H Li ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Craniospinal Irradiation ◽  
Intensity Modulated Proton Therapy ◽  
Intensity Modulated

scholarly journals A Treatment Planning Comparison of Passive-Scattering and Intensity-Modulated Proton Therapy for Typical Tumor Sites

2012 ◽  
Vol 53 (2) ◽  
pp. 272-280 ◽  
Author(s):  
Yuki KASE ◽  
Haruo YAMASHITA ◽  
Hiroshi FUJI ◽  
Yuichi YAMAMOTO ◽  
Yuehu PU ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Proton Therapy ◽  
Intensity Modulated Proton Therapy ◽  
Intensity Modulated ◽  
Passive Scattering

scholarly journals Cardiac-Sparing and Breast-Sparing Whole Lung Irradiation Using Intensity-Modulated Proton Therapy

2021 ◽  
Author(s):  
Ru Xin Wong ◽  
Jacqueline Faught ◽  
Melissa Gargone ◽  
William Myers ◽  
Matthew Krasin ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Planning Target Volume ◽  
Pediatric Patients ◽  
Lung Metastases ◽  
Target Volume ◽  
Internal Target Volume ◽  
Intensity Modulated Proton Therapy ◽  
Intensity Modulated ◽  
Lung Irradiation ◽  
Whole Lung Irradiation

Abstract Purpose Whole lung irradiation (WLI) is indicated for certain pediatric patients with lung metastases. This study investigated whether WLI delivered as intensity-modulated proton therapy (IMPT) could significantly spare the heart and breasts when compared with conventional WLI delivered with anteroposterior/posteroanterior photon fields and with intensity-modulated photon therapy (IMRT) WLI. Materials and Methods Conventional, IMRT, and IMPT plans were generated for 5 patients (aged 5-22 years). The prescription dose was 16.5 GyRBE in 1.5-GyRBE fractions. Conventional plans used 6-MV photons prescribed to the midline and a field-in-field technique to cover the planning target volume (the internal target volume [ITV] + 1 cm). IMRT plans used 6-MV photons with a 7-beam arrangement with dose prescribed to the planning target volume. IMPT plans used scenario-based optimization with 5% range uncertainty and 5-mm positional uncertainty to cover the ITV robustly. Monte Carlo dose calculation was used for all IMPT plans. Doses were compared with paired Student t test. Results The ITV Dmean was similar for the IMPT, conventional, and IMRT plans, but the IMPT plans had a lower Dmin and a higher Dmax at tissue interfaces than conventional plans (Dmean ratio: 0.96, P > .05; Dmin ratio: 0.9, P < .001; Dmax ratio: 1.1, P = .014). Dmeans for breast and heart substructures were lower with IMPT plans than with conventional/IMRT plans (heart ratios, 0.63:0.73; left ventricle ratios, 0.61:0.72; right ventricle ratios, 0.45:0.57; left atrium ratios, 0.79:0.85; right atrium ratios, 0.81:0.86; left breast ratios, 0.40:0.51; right breast ratio, 0.46:0.52; all P < .05). Conclusions IMPT resulted in comparable ITV coverage and lower mean doses to the heart and breasts when compared with other techniques. Whole lung irradiation delivered as IMPT warrants prospective evaluation in pediatric patients.

Robustly optimized hybrid intensity-modulated proton therapy for craniospinal irradiation

2021 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
ShamurailatpamDayananda Sharma ◽  
ManthalaPadannayil Noufal ◽  
Ganapathy Krishnan ◽  
Mayur Sawant ◽  
Utpal Gaikwad ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Craniospinal Irradiation ◽  
Intensity Modulated Proton Therapy ◽  
Intensity Modulated
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