scholarly journals Improving Target Volume Identification Using Biomechanical Model-Based Deformable Image Registration in MRI-Guided CT-Based Brachytherapy in Locally Advanced Cervical Cancer

2017 ◽  
Vol 99 (2) ◽  
pp. E308-E309
Author(s):  
Y. Rong ◽  
B.A. Dyer ◽  
S.H. Benedict ◽  
C. Wright ◽  
J.S. Mayadev
Keyword(s):  
Cervical Cancer ◽  
Image Registration ◽  
Locally Advanced ◽  
Biomechanical Model ◽  
Deformable Image Registration ◽  
Target Volume ◽  
Advanced Cervical Cancer ◽  
Locally Advanced Cervical Cancer ◽  
Model Based ◽  
Mri Guided

Image-Guided Brachtherapy for Locally Advanced Cervical Cancer: Can Deformable Image Registration Replace MRI Simulation?

Brachytherapy ◽  
2014 ◽  
Vol 13 ◽  
pp. S31
Author(s):  
Lauren Tait ◽  
Sonja Dieterich ◽  
Jihoon Lim ◽  
Jon-Paul Hunt ◽  
Richard K. Valicenti ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Image Registration ◽  
Locally Advanced ◽  
Deformable Image Registration ◽  
Advanced Cervical Cancer ◽  
Locally Advanced Cervical Cancer ◽  
Image Guided

The use of MRI deformable image registration for CT-based brachytherapy in locally advanced cervical cancer

Brachytherapy ◽  
2016 ◽  
Vol 15 (3) ◽  
pp. 333-340 ◽  
Author(s):  
Lauren M. Tait ◽  
David Hoffman ◽  
Stanley Benedict ◽  
Richard Valicenti ◽  
Jyoti S. Mayadev
Keyword(s):  
Cervical Cancer ◽  
Image Registration ◽  
Locally Advanced ◽  
Deformable Image Registration ◽  
Advanced Cervical Cancer ◽  
Locally Advanced Cervical Cancer

Uncertainties of deformable image registration for dose accumulation of high-dose regions in bladder and rectum in locally advanced cervical cancer

Brachytherapy ◽  
2015 ◽  
Vol 14 (6) ◽  
pp. 953-962 ◽  
Author(s):  
Swamidas V. Jamema ◽  
Umesh Mahantshetty ◽  
Else Andersen ◽  
Karsten Ø. Noe ◽  
Thomas S. Sørensen ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Image Registration ◽  
Locally Advanced ◽  
Deformable Image Registration ◽  
High Dose ◽  
Advanced Cervical Cancer ◽  
Dose Accumulation ◽  
Locally Advanced Cervical Cancer

scholarly journals MRI-guided adaptive radiotherapy in locally advanced cervical cancer from a Nordic perspective

2013 ◽  
Vol 52 (7) ◽  
pp. 1510-1519 ◽  
Author(s):  
Jacob Christian Lindegaard ◽  
Lars Ulrik Fokdal ◽  
Søren Kynde Nielsen ◽  
Jens Juul-Christensen ◽  
Kari Tanderup
Keyword(s):  
Cervical Cancer ◽  
Locally Advanced ◽  
Adaptive Radiotherapy ◽  
Advanced Cervical Cancer ◽  
Locally Advanced Cervical Cancer ◽  
Mri Guided

scholarly journals Reduction of dose to duodenum with a refined delineation method of Para-aortic region in patients with locally advanced cervical Cancer receiving prophylactic extended-field radiotherapy

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Bo Yang ◽  
Xiaoliang Liu ◽  
Ke Hu ◽  
Jie Qiu ◽  
Fuquan Zhang ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Irradiation Dose ◽  
Locally Advanced ◽  
Volumetric Modulated Arc Therapy ◽  
Vena Cava ◽  
Target Volume ◽  
High Dose ◽  
Advanced Cervical Cancer ◽  
Locally Advanced Cervical Cancer ◽  
Extended Field

Abstract Background To compare irradiation dose to the second and third portions of duodenum (Duo2 and Duo3) with a new refined and old delineation method of para-aortic region for patients with locally advanced cervical cancer (LACC) receiving prophylactic extended-field radiotherapy (EFRT). Methods Twenty consecutive patients with LACC were treated with prophylactic EFRT from January 2016 to January 2017 at our institute. Two delineation methods of para-aortic region were designed for each patient, the old delineation method ensured a full coverage of aortic and inferior vena cava, while the right paracaval region above L3 was omitted from CTV in the new delineation method. Patients received a dose of 50.4Gy in 28 fractions for PCTV and a dose of 60.2Gy in 28 fractions for PGTV with volumetric-modulated arc therapy (VMRT). The dose delivered to Duo2 and Duo3 with these two delineation methods were compared. Results All treatment plans achieved excellent target volume coverage with 95% of PCTV receiving 50.4Gy and 95% of PGTV receiving 60.2Gy. There was no difference between delineation methods in low dose level (V5, V10, V15, V20, V25) for Duo2 and Duo3. The V30, V35, V40, V45, V50, Dmax, Dmean and D2cc for Duo2 with the new and old delineation methods were 55.76% vs 80.54% (P = 0.009), 34.72% vs 70.91% (P < 0.001), 18.69% vs 55.46% (P < 0.001), 8.20% vs 41.49% (P < 0.001), 1.86% vs 21.60% (P < 0.001), 49.58Gy vs 52.91Gy (P = 0.002), 30.38Gy vs 39.22Gy (P = 0.001) and 37.90Gy vs 48.64Gy (P < 0.001) respectively. For Duo3, the new delineation method achieved significant advantages in V30, V35, V40, V45, V50 and Dmean over the old one (96.82% vs 99.25%, P = 0.021; 89.65% vs 97.21%, P = 0.001; 79.50% vs 93.18%, P < 0.001; 65.63% vs 82.93%, P < 0.001; 43.39% vs 65.60%, P < 0.001; 46.09Gy vs 49.24Gy, P < 0.001), no deference was observed regarding D2cc and Dmax with these two delineation methods. Conclusion With the new delineation method of para-aortic area in prophylactic EFRT, significant reduction of irradiation dose to the second and third portions of duodenum in high dose area was obtained. This may further lower the incidence of duodenal toxicity when performing prophylactic EFRT for patients with LACC.

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