scholarly journals The Effect of Bladder Volume on RT Dosimetry during Multiple Sessions of Intracavitary Brachytherapy for Cervical Cancer

2019 ◽  
Vol 105 (1) ◽  
pp. E341-E342
Author(s):  
Z.Y. Xu ◽  
L. Yang ◽  
A.T. Chang ◽  
L. Shen ◽  
S.K. Hui ◽  
...  
2019 ◽  
Vol 19 (3) ◽  
pp. 277-280
Author(s):  
N. Chakravarty ◽  
M. K. Semwal ◽  
G. Trivedi ◽  
V. Suhag ◽  
M. Jain ◽  
...  

AbstractAim:To study 2D and 3D dosimetric values for bladder and rectum, and the influence of bladder volume on bladder dose in high dose rate (HDR) intracavitary brachytherapy (ICBT). The large patient data incorporated in this study would better represent the inherent variations in many parameters affecting dosimetry in HDR-ICBT.Material and Methods:We prospectively collected data for 103 consecutive cervical cancer patients (over 310 HDR fractions) undergoing CT-based HDR-ICBT at our centre. Correlation among bladder and rectum maximum volume doses and corresponding International Commission on Radiation Units and Measurement (ICRU) point doses were estimated and analysed. Impact of bladder volume on bladder maximum dose was assessed.Results:The ICRU point doses to bladder and rectum varied from the volumetric doses to these organs. Further, bladder volume poorly correlated with bladder maximum dose for volume variations encountered in the clinical practice at our centre.Findings:ICRU point doses to bladder and rectum are less likely to correlate with long-term toxicities to these organs. Further, in clinical practice where inter-fraction bladder volume does not vary widely there is no correlation between bladder volume and bladder dose.


2017 ◽  
Vol 46 (1) ◽  
pp. 8-13 ◽  
Author(s):  
Tugana Akbas ◽  
Gamze Ugurluer ◽  
Meltem Acil ◽  
Taner Arpaci ◽  
Meltem Serin

2012 ◽  
Vol 103 ◽  
pp. S101
Author(s):  
T. Toita ◽  
R. Kitagawa ◽  
T. Hamano ◽  
K. Umayahara ◽  
Y. Hirashima ◽  
...  

Brachytherapy ◽  
2013 ◽  
Vol 12 ◽  
pp. S56-S57
Author(s):  
Lisa Klepczyk ◽  
Sui Shen ◽  
Jun Duan ◽  
Robert Y. Kim

2016 ◽  
Vol 57 (6) ◽  
pp. 677-683 ◽  
Author(s):  
Yoshifumi Oku ◽  
Hidetaka Arimura ◽  
Tran Thi Thao Nguyen ◽  
Yoshiyuki Hiraki ◽  
Masahiko Toyota ◽  
...  

Abstract This study investigates whether in-room computed tomography (CT)-based adaptive treatment planning (ATP) is robust against interfractional location variations, namely, interfractional organ motions and/or applicator displacements, in 3D intracavitary brachytherapy (ICBT) for uterine cervical cancer. In ATP, the radiation treatment plans, which have been designed based on planning CT images (and/or MR images) acquired just before the treatments, are adaptively applied for each fraction, taking into account the interfractional location variations. 2D and 3D plans with ATP for 14 patients were simulated for 56 fractions at a prescribed dose of 600 cGy per fraction. The standard deviations (SDs) of location displacements (interfractional location variations) of the target and organs at risk (OARs) with 3D ATP were significantly smaller than those with 2D ATP (P < 0.05). The homogeneity index (HI), conformity index (CI) and tumor control probability (TCP) in 3D ATP were significantly higher for high-risk clinical target volumes than those in 2D ATP. The SDs of the HI, CI, TCP, bladder and rectum D2cc, and the bladder and rectum normal tissue complication probability (NTCP) in 3D ATP were significantly smaller than those in 2D ATP. The results of this study suggest that the interfractional location variations give smaller impacts on the planning evaluation indices in 3D ATP than in 2D ATP. Therefore, the 3D plans with ATP are expected to be robust against interfractional location variations in each treatment fraction.


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