Intratumoral Hydrogen Peroxide With Radiation Therapy in Locally Advanced Breast Cancer: Results From a Phase 1 Clinical Trial

Samantha Nimalasena; Lone Gothard; Selvakumar Anbalagan; Steven Allen; Victoria Sinnett; Kabir Mohammed; Gargi Kothari; Annette Musallam; Claire Lucy; Sheng Yu; Gift Nayamundanda; Anna Kirby; Gill Ross; Elinor Sawyer; Fiona Castell; Susan Cleator; Imogen Locke; Diana Tait; Charlotte Westbury; Virginia Wolstenholme; Carol Box; Simon P. Robinson; John Yarnold; Navita Somaiah

doi:10.1016/j.ijrobp.2020.06.022

Intratumoral Hydrogen Peroxide With Radiation Therapy in Locally Advanced Breast Cancer: Results From a Phase 1 Clinical Trial

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2020.06.022 ◽

2020 ◽

Vol 108 (4) ◽

pp. 1019-1029

Author(s):

Samantha Nimalasena ◽

Lone Gothard ◽

Selvakumar Anbalagan ◽

Steven Allen ◽

Victoria Sinnett ◽

...

Keyword(s):

Breast Cancer ◽

Clinical Trial ◽

Hydrogen Peroxide ◽

Radiation Therapy ◽

Advanced Breast Cancer ◽

Locally Advanced Breast Cancer ◽

Phase 1 ◽

Locally Advanced ◽

Advanced Breast ◽

Phase 1 Clinical Trial

Trial Combining Taxol and Radiation Therapy for Treatment of Locally Advanced Breast Cancer. Phase 1.

10.21236/ada323556 ◽

1996 ◽

Author(s):

Peter B. Schiff

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Advanced Breast Cancer ◽

Locally Advanced Breast Cancer ◽

Phase 1 ◽

Locally Advanced ◽

Advanced Breast

1844 Preliminary treatment results of new hypoxic radiosensitizer ’KORTUC’ (Kochi oxydol-radiation therapy for unresectable carcinomas) containing hydrogen peroxide and sodium hyaluronate for massive unresectable locally advanced breast cancer

European Journal of Cancer ◽

10.1016/s0959-8049(16)30794-8 ◽

2015 ◽

Vol 51 ◽

pp. S280

Author(s):

T. Hamada ◽

T. Shinbo ◽

N. Yoshikawa ◽

H. Yoshioka ◽

Y. Tanaka ◽

...

Keyword(s):

Breast Cancer ◽

Hydrogen Peroxide ◽

Radiation Therapy ◽

Advanced Breast Cancer ◽

Locally Advanced Breast Cancer ◽

Locally Advanced ◽

Sodium Hyaluronate ◽

Advanced Breast ◽

Preliminary Treatment ◽

Treatment Results

Exclusive radiation therapy after neoadjuvant chemotherapy for locally advanced breast cancer: experience of a single academic institution

European Journal of Cancer ◽

10.1016/s0959-8049(02)80501-9 ◽

2002 ◽

Vol 38 (11) ◽

pp. S150

Author(s):

J Caudrelier

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Neoadjuvant Chemotherapy ◽

Advanced Breast Cancer ◽

Locally Advanced Breast Cancer ◽

Locally Advanced ◽

Academic Institution ◽

Advanced Breast ◽

Cancer Experience

In regard to Kao et al.: Concomitant radiation therapy and paclitaxel for unresectable locally advanced breast cancer: Results from two consecutive Phase I/II trials (Int J Radiat Oncol Biol Phys 2005;61:1045–1053)

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2005.06.045 ◽

2005 ◽

Vol 63 (4) ◽

pp. 1276 ◽

Cited By ~ 2

Author(s):

Silvia C. Formenti

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Phase I ◽

Advanced Breast Cancer ◽

Radiat Oncol Biol Phys ◽

Locally Advanced Breast Cancer ◽

Locally Advanced ◽

Advanced Breast ◽

Consecutive Phase

Treatment of stage IIIA/B locally advanced breast cancer (LABC) with induction chemotherapy (CT) and hormonal synchronization (HS) followed by radiation therapy (RT) with or without mastectomy

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/0360-3016(86)90620-6 ◽

1986 ◽

Vol 12 ◽

pp. 152

Author(s):

J.L. Bader ◽

M.E. Lippman ◽

C.S. Bagley ◽

S. Swain ◽

R.A. Sorace ◽

...

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Advanced Breast Cancer ◽

Induction Chemotherapy ◽

Locally Advanced Breast Cancer ◽

Locally Advanced ◽

Advanced Breast ◽

Stage Iiia

Preoperative 5-fluorouracil and radiation therapy for locally advanced breast cancer

The American Journal of Surgery ◽

10.1016/s0002-9610(97)00198-0 ◽

1997 ◽

Vol 174 (6) ◽

pp. 705-708 ◽

Cited By ~ 18

Author(s):

Kristin A. Skinner ◽

Gary Dunnington ◽

Howard Silberman ◽

Barbara Florentine ◽

Darcy Spicer ◽

...

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Advanced Breast Cancer ◽

Locally Advanced Breast Cancer ◽

Locally Advanced ◽

Advanced Breast

Radiation Therapy for Locally Advanced Breast Cancer

The Breast ◽

10.1016/b978-0-323-35955-9.00053-2 ◽

2018 ◽

pp. 726-735.e2

Author(s):

Kilian E. Salerno ◽

Michael D. Mix

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Advanced Breast Cancer ◽

Locally Advanced Breast Cancer ◽

Locally Advanced ◽

Advanced Breast

Upper Extremity Toxicity With Adjuvant Comprehensive Radiation Therapy for Locally-Advanced Breast Cancer

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2013.06.620 ◽

2013 ◽

Vol 87 (2) ◽

pp. S239

Author(s):

M.C. Roach ◽

L. Ochoa ◽

C.M. Bradbury ◽

M.A. Thomas ◽

I. Zoberi

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Advanced Breast Cancer ◽

Upper Extremity ◽

Locally Advanced Breast Cancer ◽

Locally Advanced ◽

Advanced Breast

Low HER2/neu gene expression is associated with pathological response to concurrent paclitaxel and radiation therapy in locally advanced breast cancer

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/s0360-3016(01)02655-4 ◽

2002 ◽

Vol 52 (2) ◽

pp. 397-405 ◽

Cited By ~ 25

Author(s):

Silvia C Formenti ◽

Darcy Spicer ◽

Kristin Skinner ◽

Deidre Cohen ◽

Susan Groshen ◽

...

Keyword(s):

Breast Cancer ◽

Gene Expression ◽

Radiation Therapy ◽

Advanced Breast Cancer ◽

Locally Advanced Breast Cancer ◽

Locally Advanced ◽

Pathological Response ◽

Advanced Breast

Five-year Local Control Results of Preoperative Paclitaxel with Concurrent Radiation Therapy in Locally Advanced Breast Cancer

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2010.07.505 ◽

2010 ◽

Vol 78 (3) ◽

pp. S209-S210

Author(s):

A. Chakravarthy ◽

S. Adams ◽

D. Spicer ◽

S. Lymberis ◽

J.D. Goldberg ◽

...

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Advanced Breast Cancer ◽

Local Control ◽

Locally Advanced Breast Cancer ◽

Locally Advanced ◽

Advanced Breast