Synthesis, crystal structure, DNA binding properties and antioxidant activities of transition metal complexes with 3-carbaldehyde-chromone semicarbazone

2010 ◽  
Vol 13 (10) ◽  
pp. 1213-1216 ◽  
Author(s):  
Yong Li ◽  
Zheng-Yin Yang ◽  
Zhen-Chuan Liao ◽  
Zi-Chao Han ◽  
Zeng-Chen Liu
Keyword(s):  
Crystal Structure ◽  
Dna Binding ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Antioxidant Activities ◽  
Binding Properties ◽  
Dna Binding Properties

Synthesis, Crystal Structure, DNA-binding Properties and Antioxidant Activities of a Lutetium(III) Complex with the Bis(N-salicylidene)-3- oxapentane-1,5-diamine Ligand

2013 ◽  
Vol 68 (3) ◽  
pp. 257-266 ◽  
Author(s):  
Guolong Pan ◽  
Yuchen Bai ◽  
Hua Wang ◽  
Jin Kong ◽  
Furong Shi ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Dna Binding ◽  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Binding Mode ◽  
Binding Properties ◽  
Metal Centers ◽  
Spectrophotometric Methods ◽  
Dna Binding Properties

A Schiff base ligand bis(N-salicylidene)-3-oxapentane-1,5-diamine (H2L) and its lutetium(III) complex, with composition Lu2(L)2(NO3)2, were synthesized and characterized by physico-chemical and spectroscopic methods. The crystal structure of the Lu(III) complex has been determined by single-crystal X-ray diffraction. It reveals a centrosymmetric binuclear neutral entity where Lu(III) metal centers are bridged by two phenoxo oxygen atoms. The DNA-binding properties of the Lu(III) complex were investigated by spectrophotometric methods and viscosity measurements, and the results suggest that the Lu(III) complex binds to DNA via a groove binding mode. Additionally, the antioxidant activity of the Lu(III) complex was determined by the superoxide and hydroxyl radical scavenging methods in vitro, which indicate that it is a scavenger for OH· and O-· 2 radicals.

Tuned structure and DNA binding properties of metal complexes based on a new 4-acylpyrazolone derivative

2020 ◽  
Vol 44 (6) ◽  
pp. 2281-2290
Author(s):  
Wei Xi ◽  
Fu-Qiang Song ◽  
Xue-Li Xia ◽  
Xue-Qin Song
Keyword(s):  
Dna Binding ◽  
Transition Metal ◽  
Metal Complexes ◽  
Metal Cations ◽  
Transition Metal Compounds ◽  
Binding Properties ◽  
Metal Compounds ◽  
Dna Binding Properties

The structure and DNA binding performance of three transition metal compounds based on a new pyrazolone ligand were tuned effectively by changing both metal cations and anions.

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