Erythema nodosum–like lesions in treated Whipple's disease: Signs of immune reconstitution inflammatory syndrome

2009 ◽  
Vol 60 (2) ◽  
pp. 277-288 ◽  
Author(s):  
Jörg Schaller ◽  
J. Andrew Carlson
2010 ◽  
Vol 60 (1) ◽  
pp. 79-82 ◽  
Author(s):  
Jean-Christophe Lagier ◽  
Florence Fenollar ◽  
Hubert Lepidi ◽  
Eric Liozon ◽  
Didier Raoult

2021 ◽  
Vol 14 (6) ◽  
pp. e243633
Author(s):  
Patrick Hofmann ◽  
Nina Durisch ◽  
Claudia Buetikofer ◽  
Birgit Maria Helmchen

We present the case of a 70-year-old woman with a history of seronegative arthritis, recurrent pleural effusion and weight loss. A prior lung biopsy had revealed non-caseating epithelioid cell granulomas without evidence for microbial organisms on special stains. Intestinal biopsy findings where suspicious for Whipple’s disease, which was confirmed by PCR testing, both on the intestinal and retrospectively on the lung tissue. Treatment with ceftriaxone resulted in clinical deterioration with fever, arthritis and recurrent pleuritis consistent with immune reconstitution inflammatory syndrome. Dose increase of glucocorticoids and therapy rotation to doxycycline and hydroxychloroquine resulted in rapid clinical improvement.


2013 ◽  
Vol 190 (5) ◽  
pp. 2354-2361 ◽  
Author(s):  
Verena Moos ◽  
Gerhard E. Feurle ◽  
Katina Schinnerling ◽  
Anika Geelhaar ◽  
Julian Friebel ◽  
...  

2015 ◽  
Vol 82 (2) ◽  
pp. 122-124 ◽  
Author(s):  
Marielle Vayssade ◽  
Anne Tournadre ◽  
Michel D’Incan ◽  
Martin Soubrier ◽  
Jean-Jacques Dubost

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