Improvements in health-related quality of life with once-daily (evening) or twice-daily dosing of mometasone furoate dry powder inhaler (MF-DPI) in children with asthma

2005 ◽  
Vol 115 (2) ◽  
pp. S5
Author(s):  
M. Noonan ◽  
M.E. Ruff ◽  
P. Chervinsky ◽  
W. Berger
2012 ◽  
Vol 24 (3) ◽  
pp. 472-489 ◽  
Author(s):  
Alison Crosbie

ObjectiveAsthma is a leading cause of chronic illness in children, impacting heavily on their daily life and participation in physical activity. The purpose of this systematic review was to investigate the evidence for the use of physical therapy to improve pulmonary function and aerobic capacity in children with asthma. Furthermore, the review aims to update previous literature on the effect of exercise on health related quality of life.MethodsA search was conducted for randomized control trials (RCTs) using the electronic databases Medline, Embase, SPORTDiscus, AMED, CINAHL, and The Cochrane Central Register of Controlled Trials. Studies were included if the participants were asthmatic children aged 6–18 years participating in any mode of physical exercise. Studies were reviewed for study quality, participant details, exercise intervention details, and intervention outcomes.ResultsA total of 16 studies and 516 subjects met inclusion criteria for review. Severity of asthma ranged from mild to severe. No improvement in pulmonary function was observed. Physical training led to an increase in aerobic capacity as measured by VO2max (mL/kg/min).ConclusionsFindings suggest that physical training does not improve pulmonary function in children with asthma, but does increase aerobic capacity. The small number of studies investigating quality of life suggests that physical training does improve health related quality of life; however further well designed randomized control trials are needed to verify these findings.


1997 ◽  
Vol 4 (3) ◽  
pp. 145-151
Author(s):  
Elizabeth F Juniper

Many clinicians now recognize the importance of incorporating an assessment of health-related quality of life (HRQL) into their clinical studies and practices. Conventional clinical measures provide valuable information about the status of the affected organ system but rarely capture the functional impairments (physical, emotional and social) that are important to patients in their everyday lives. To obtain a complete picture of a patient’s health status, both the conventional clinical indices and the patient's HRQL must be measured. Both adults and children with asthma are distressed by symptoms, such as shortness of breath, cough and chest tightness, and they are limited in their day-to-day activities, such as sports, employment or school work and participation in activities with friends. In addition, both adults and children with asthma are concerned about having asthma, fearful of not having their medications when they need them and frightened of having an asthma attack. They become very frustrated, and children in particular often feel different and isolated from their friends. Disease-specific HRQL questionnaires have been developed and validated for both adults and children with asthma. This paper provides a review of these questionnaires and identifies their strengths and weaknesses. The questionnaires chosen for review have good measurement properties and validity and can be used in both clinical trials and clinical practice to assess the impact of asthma on a patient’s life. Because one of the aims of treatment is to ensure that patients benefit from treatment, an essential component of clinical assessment should be evaluation of HRQL.


Author(s):  
Phillip E. Korenblat ◽  
Jacques Hebert ◽  
Nicola Gallagher ◽  
Carmen Martin ◽  
Donald Banerji ◽  
...  

2012 ◽  
Vol 30 (8) ◽  
pp. 697-712 ◽  
Author(s):  
Wendy J. Ungar ◽  
Katherine Boydell ◽  
Sharon Dell ◽  
Brian M. Feldman ◽  
Deborah Marshall ◽  
...  

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