Challenges With Measurement Of IgE Antibodies To Minor Components In Food Allergy: Eosinophilic Esophagitis, Peanut Allergy, and Delayed Anaphylaxis To Mammalian Meat

2014 ◽  
Vol 133 (2) ◽  
pp. AB260 ◽  
Author(s):  
Anubha Tripathi ◽  
Lisa J. Workman ◽  
Scott Commins ◽  
Barrett Barnes ◽  
Robert G. Hamilton ◽  
...  
Keyword(s):  
Food Allergy ◽  
Eosinophilic Esophagitis ◽  
Peanut Allergy ◽  
Minor Components ◽  
Ige Antibodies ◽  
Delayed Anaphylaxis ◽  
Mammalian Meat

Prevention of food allergy

2019 ◽  
Vol 40 (6) ◽  
pp. 450-452 ◽  
Author(s):  
Ashley L. Devonshire ◽  
Rachel Glick Robison
Keyword(s):  
Food Allergy ◽  
Peanut Allergy ◽  
Immunoglobulin E ◽  
Skin Prick Testing ◽  
Clinical Manifestations ◽  
Conclusive Evidence ◽  
Severe Atopic Dermatitis ◽  
Early Introduction ◽  
Infant Diet ◽  
Specific Immunoglobulin E

Primary prevention and secondary prevention in the context of food allergy refer to prevention of the development of sensitization (i.e., the presence of food-specific immunoglobulin E (IgE) as measured by skin-prick testing and/or laboratory testing) and sensitization plus the clinical manifestations of food allergy, respectively. Until recently, interventions that target the prevention of food allergy have been limited. Although exclusive breast-feeding for the first 6 months of life has been a long-standing recommendation due to associated health benefits, recommendations regarding complementary feeding in infancy have significantly changed over the past 20 years. There now is evidence to support early introduction of peanut into the diet of infants with egg allergy, severe atopic dermatitis, or both diagnoses, defined as high risk for peanut allergy, to try to prevent development of peanut allergy. Although guideline-based recommendations are not available for early introduction of additional allergenic foods, this topic is being actively studied. There is no evidence to support additional dietary modification of the maternal or infant diet for the prevention of food allergy. Similarly, there is no conclusive evidence to support maternal avoidance diets for the prevention of food allergy.

scholarly journals Food allergy, eosinophilic esophagitis, and the enigma of IgG4

2019 ◽  
Vol 122 (6) ◽  
pp. 563-564 ◽  
Author(s):  
Emily C. McGowan ◽  
Thomas A.E. Platts-Mills ◽  
Jeffrey M. Wilson
Keyword(s):  
Food Allergy ◽  
Eosinophilic Esophagitis

A review of the evidence linking eosinophilic esophagitis and food allergy

2015 ◽  
Vol 36 (1) ◽  
pp. 26-33 ◽  
Author(s):  
Samantha K. Lin ◽  
Geetika Sabharwal ◽  
Gisoo Ghaffari
Keyword(s):  
Food Allergy ◽  
Eosinophilic Esophagitis

Determinants of Peanut Allergy in an Observational Study (CoFAR2) of Food Allergy

2016 ◽  
Vol 137 (2) ◽  
pp. AB152 ◽  
Author(s):  
Scott H. Sicherer ◽  
Robert A. Wood ◽  
Tamara T. Perry ◽  
Brian P. Vickery ◽  
Stacie M. Jones ◽  
...  
Keyword(s):  
Food Allergy ◽  
Observational Study ◽  
Peanut Allergy

scholarly journals Recurring Anaphylaxis: A New Line of Questioning for your HPI

2020 ◽  
Vol 3 (1) ◽  
pp. 18-21
Author(s):  
Wahid Lana ◽  
◽  
Aziz Sameh ◽  
Abraham Christina ◽  
◽  
...  
Keyword(s):  
Allergic Reaction ◽  
Unknown Etiology ◽  
Shortness Of Breath ◽  
Tick Bites ◽  
Ige Antibody ◽  
Delayed Onset ◽  
The Past ◽  
Delayed Anaphylaxis ◽  
Life Threatening ◽  
Mammalian Meat

Anaphylaxis is a serious life-threatening allergic reaction that typically has an immediate onset. It can present as flushing, angioedema, shortness of breath, rash and result in death if not treated immediately. In the past ten years, an emerging cause of delayed anaphylaxis has been identified. An IgE antibody to a mammalian oligosaccharide epitope (alpha-gal, or galactose-alpha-1,3-galactose) has been linked to both immediate and delayed onset anaphylaxis. The immediate form is associated with the first exposure to cetuximab; whereas the delayed onset occurs after ingestion of mammalian meat such as beef and pork. The presentation can develop 2-6 hours after ingestion. This IgE antibody to alpha-gal is strongly suggested that Lone Star tick bites have been the culprit. It is imperative when caring for an anaphylaxis patient of unknown etiology, to consider a line of questioning to not only include recent tick bites, but also last 2-3 meals ingested to identify if mammalian meat may have been the trigger.

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