scholarly journals Persistence and evolution of allergen-specific IgE repertoires during subcutaneous specific immunotherapy

2016 ◽  
Vol 137 (5) ◽  
pp. 1535-1544 ◽  
Author(s):  
Mattias Levin ◽  
Jasmine J. King ◽  
Jacob Glanville ◽  
Katherine J.L. Jackson ◽  
Timothy J. Looney ◽  
...  
Keyword(s):  
Specific Immunotherapy ◽  
Specific Ige ◽  
Subcutaneous Specific Immunotherapy

Immunotheraphy in Allergic Diseases

2018 ◽  
Vol 24 (11) ◽  
pp. 1174-1194
Author(s):  
Albert Roger ◽  
Maria Basagana ◽  
Aina Teniente-Serra ◽  
Nathalie Depreux ◽  
Yanina Jurgens ◽  
...  
Keyword(s):  
Specific Immunotherapy ◽  
Allergic Diseases ◽  
Specific Ige ◽  
World Population ◽  
Allergen Specific Immunotherapy ◽  
Routes Of Administration ◽  
Disease Modifying Therapy ◽  
History Of ◽  
Ige Mediated ◽  
Special Case

The prevalence of allergic diseases is increasing worldwide. It is estimated that more than 30% of the world population is now affected by one or more allergic conditions and a high proportion of this increase is in young people. The diagnosis of allergy is dependent on a history of symptoms on exposure to an allergen together with the detection of allergen-specific IgE. Accurate diagnosis of allergies opens up therapeutic options. Allergen specific immunotherapy is the only successful disease-modifying therapy for IgE-mediated allergic diseases. New therapeutic strategies have been developed or are currently under clinical trials. Besides new routes of administration, new types of allergens are being developed. The use of adjuvants may amplify the immune response towards tolerance to the antigens. In this review, we analyze different antigen-specific immunotherapies according to administration route, type of antigens and adjuvants, and we address the special case of food allergy.

In vivo and in vitro specific IgE determination after specific immunotherapy with Hymenoptera venom: parameter to evaluate treatment success?

2013 ◽  
Vol 1 (1) ◽  
pp. 51-55
Author(s):  
Cynthia Mafra Fonseca de Lima ◽  
Alexandra Sayuri Watanabe ◽  
Jorge Kalil ◽  
Fábio Fernandes Morato Castro ◽  
Clóvis Eduardo Santos Galvão
Keyword(s):  
Specific Immunotherapy ◽  
Treatment Success ◽  
Specific Ige ◽  
Hymenoptera Venom ◽  
Ige Determination

scholarly journals Reduction in allergen-specific IgE binding as measured by microarray: A possible surrogate marker for effects of specific immunotherapy

2015 ◽  
Vol 136 (3) ◽  
pp. 806-809.e7 ◽  
Author(s):  
Eva Wollmann ◽  
Christian Lupinek ◽  
Michael Kundi ◽  
Regina Selb ◽  
Verena Niederberger ◽  
...  
Keyword(s):  
Specific Immunotherapy ◽  
Surrogate Marker ◽  
Specific Ige ◽  
Ige Binding
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