Drug Provocation Tests in Patients with Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Acetaminophen Hypersensitivity Reactions

2017 ◽  
Vol 139 (2) ◽  
pp. AB40
Author(s):  
Wat Mitthamsiri ◽  
Panithan Pradubpongsa ◽  
Atik Sangasapaviliya ◽  
Tadech Boonpiyathad
2021 ◽  
Vol 40 (1) ◽  
pp. 37-43
Author(s):  
Laura Levantino ◽  
Cristiana Corrado ◽  
Laura Badina ◽  
Sara Lega ◽  
Egidio Barbi

Non-steroidal anti-inflammatory drugs (NSAIDs) are the main triggers of drug hypersensitivity reactions in children. According to the EAACI latest classification NSAIDs hypersensitivity reactions are differentiated into cross-reactive reactions, with non-immunological mechanisms (based on COX-1 inhibition), and selective reactions, with immunological mechanisms. Paediatric clinical manifestations of NSAID hypersensitivity are typically cutaneous, but sometimes, similarly to anaphylaxis, can involve other systems, especially the respiratory one. Differentiating between NSAID intolerance and NSAID allergy through drug provocation tests is crucial for the patient because the two clinical entities require different management.


2013 ◽  
Vol 24 (2) ◽  
pp. 151-159 ◽  
Author(s):  
Maria A. Zambonino ◽  
Maria J. Torres ◽  
Candelaria Muñoz ◽  
Gloria Requena ◽  
Cristobalina Mayorga ◽  
...  

Allergy ◽  
2020 ◽  
Vol 75 (6) ◽  
pp. 1423-1434 ◽  
Author(s):  
Dunya Nohra ◽  
Nicolas Molinari ◽  
Pascal Demoly ◽  
Anca‐Mirela Chiriac

2019 ◽  
Vol 143 (2) ◽  
pp. AB29
Author(s):  
Natalia Pérez-Sánchez ◽  
Inmaculada Doña ◽  
Maria Salas ◽  
Testera-Montes Almudena ◽  
Francisca Gomez ◽  
...  

2016 ◽  
Vol 171 (3-4) ◽  
pp. 269-275 ◽  
Author(s):  
Eva Rebelo Gomes ◽  
Luísa Geraldes ◽  
Ângela Gaspar ◽  
Daniela Malheiro ◽  
Susana Cadinha ◽  
...  

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