Clinical Characterization of a Large Population of Subjects with Respiratory Vs Cutaneous Non-Steroidal Anti-Inflammatory Drugs (NSAID) Hypersensitivity Reactions

2017 ◽  
Vol 139 (2) ◽  
pp. AB45
Author(s):  
Jesus Verge ◽  
Inmaculada DoÑa ◽  
Ibon Eguiluz Gracia ◽  
Ana Prieto del Prado ◽  
Luisa Galindo ◽  
...  
2019 ◽  
Vol 143 (2) ◽  
pp. AB29
Author(s):  
Natalia Pérez-Sánchez ◽  
Inmaculada Doña ◽  
Maria Salas ◽  
Testera-Montes Almudena ◽  
Francisca Gomez ◽  
...  

1996 ◽  
Vol 10 (7) ◽  
pp. 451-459 ◽  
Author(s):  
John L Wallace

The toxicity of nonsteroidal anti-inflammatory drugs (NSAIDs) in the gastrointestinal tract continues to be a major limitation to their use in the treatment of inflammatory disorders. Better understanding of the pathogenesis of NSAID enteropathy has facilitated the development of novel NSAIDs that spare the gastrointestinal tract. In particular, identification and characterization of the inducible form of prostaglandin synthase has led to the design of novel NSAIDs that specifically target that enzyme. The pathogenesis of NSAID gastroenteropathy is reviewed, as are the strategies that have been used in the past and are used now to develop NSAIDs that spare the gastrointestinal tract. Also reviewed are the strategies being employed to achieve this goal in the future.


2016 ◽  
Vol 171 (3-4) ◽  
pp. 269-275 ◽  
Author(s):  
Eva Rebelo Gomes ◽  
Luísa Geraldes ◽  
Ângela Gaspar ◽  
Daniela Malheiro ◽  
Susana Cadinha ◽  
...  

2017 ◽  
Vol 22 (45) ◽  
pp. 6784-6802 ◽  
Author(s):  
Inmaculada Dona ◽  
Maria Salas ◽  
James Perkins ◽  
Esther Barrionuevo ◽  
Francesco Gaeta ◽  
...  

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