P2-221: ABT-089, a neuronal nicotinic receptor partial agonist, reverses scopolamine-induced cognitive deficits in healthy normal subjects

2009 ◽  
Vol 5 (4S_Part_11) ◽  
pp. P325-P325 ◽  
Author(s):  
Jeffrey D. Baker ◽  
Robert A. Lenz ◽  
Charles Locke ◽  
Keith Wesnes ◽  
Paul Maruff ◽  
...  
Keyword(s):  
Cognitive Deficits ◽  
Nicotinic Receptor ◽  
Partial Agonist ◽  
Normal Subjects ◽  
Neuronal Nicotinic Receptor

scholarly journals Phase IIb Trial of an α7 Nicotinic Receptor Partial Agonist With and Without Nicotine Patch for Withdrawal-Associated Cognitive Deficits and Tobacco Abstinence

2018 ◽  
Vol 38 (4) ◽  
pp. 307-316 ◽  
Author(s):  
Randi Melissa Schuster ◽  
Gladys N. Pachas ◽  
Luke Stoeckel ◽  
Corinne Cather ◽  
Mireya Nadal ◽  
...  
Keyword(s):  
Cognitive Deficits ◽  
Nicotinic Receptor ◽  
Partial Agonist ◽  
Nicotine Patch

Receptor Binding Thermodynamics at the Neuronal Nicotinic Receptor

2004 ◽  
Vol 4 (3) ◽  
pp. 361-368 ◽  
Author(s):  
P.A. Borea ◽  
K. Varani ◽  
S.G., S. Merighi ◽  
A.D. Piaz ◽  
P. Gilli ◽  
...  
Keyword(s):  
Receptor Binding ◽  
Nicotinic Receptor ◽  
Neuronal Nicotinic Receptor ◽  
Binding Thermodynamics

Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor

Nature ◽  
1991 ◽  
Vol 353 (6347) ◽  
pp. 846-849 ◽  
Author(s):  
F. Revah ◽  
D. Bertrand ◽  
J.-L Galzi ◽  
A. Devillers-Thiéry ◽  
C. Mulle ◽  
...  
Keyword(s):  
Nicotinic Receptor ◽  
Neuronal Nicotinic Receptor

Upregulation of Neuronal Nicotinic Receptor Subunits α4,β2,and α7 in Transgenic Mice Overexpressing Human Acetylcholinesterase

2002 ◽  
Vol 18 (3) ◽  
pp. 211-222 ◽  
Author(s):  
Marie M. Svedberg ◽  
Anne-Lie Svensson ◽  
Mary Johnson ◽  
Mandy Lee ◽  
Osnat Cohen ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Nicotinic Receptor ◽  
Neuronal Nicotinic Receptor
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