P1-399: SUVN-I1307014: NOVEL M1 MUSCARINIC ACETYLCHOLINE RECEPTOR POSITIVE ALLOSTERIC MODULATOR FOR POTENTIAL TREATMENT OF ALZHEIMER'S DISEASE

Allosteric Modulator ◽

Potential Treatment ◽

P2-317: Suvn-i1312004, a novel M1 muscarinic acetylcholine receptor-positive allosteric modulator: Potential for the treatment of Alzheimer's disease

Alzheimer s & Dementia ◽

10.1016/j.jalz.2015.06.859 ◽

2015 ◽

Vol 11 (7S_Part_13) ◽

pp. P615-P616

Author(s):

Renny Abraham ◽

Ramkumar Subramanian ◽

Rajesh Babu Medapati ◽

Ravirala Venkateshwarlu ◽

Sumanth Yathavakilla ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

Allosteric Modulator ◽

Allosteric modulation of the M1 muscarinic acetylcholine receptor: improving cognition and a potential treatment for schizophrenia and Alzheimer's disease

Drug Discovery Today ◽

10.1016/j.drudis.2013.09.005 ◽

2013 ◽

Vol 18 (23-24) ◽

pp. 1185-1199 ◽

Cited By ~ 78

Author(s):

Bruce J. Melancon ◽

James C. Tarr ◽

Joseph D. Panarese ◽

Michael R. Wood ◽

Craig W. Lindsley

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

Allosteric Modulation ◽

Potential Treatment ◽

M1 muscarinic acetylcholine receptor in Alzheimer’s disease

Neuroscience Bulletin ◽

10.1007/s12264-013-1406-z ◽

2014 ◽

Vol 30 (2) ◽

pp. 295-307 ◽

Cited By ~ 65

Author(s):

Shangtong Jiang ◽

Yanfang Li ◽

Cuilin Zhang ◽

Yingjun Zhao ◽

Guojun Bu ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

4-Phenylpyridin-2-one Derivatives: A Novel Class of Positive Allosteric Modulator of the M1 Muscarinic Acetylcholine Receptor

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.5b01562 ◽

2015 ◽

Vol 59 (1) ◽

pp. 388-409 ◽

Cited By ~ 27

Author(s):

Shailesh N. Mistry ◽

Manuela Jörg ◽

Herman Lim ◽

Natalie B. Vinh ◽

Patrick M. Sexton ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Allosteric Modulator ◽

A M1 muscarinic acetylcholine receptor positive allosteric modulator improves pathology and cognitive deficits in female APPswe/PSEN1ΔE9 mice

British Journal of Pharmacology ◽

10.1111/bph.15750 ◽

2021 ◽

Author(s):

Khaled S. Abd‐Elrahman ◽

Shaarika Sarasija ◽

Tash‐Lynn L. Colson ◽

Stephen S. G. Ferguson

Keyword(s):

Acetylcholine Receptor ◽

Cognitive Deficits ◽

Allosteric Modulator ◽

From Structure to Clinic: Discovery of A M1 Muscarinic Acetylcholine Receptor Agonist for the Treatment of Memory Loss in Alzheimer's Disease

SSRN Electronic Journal ◽

10.2139/ssrn.3641933 ◽

2020 ◽

Author(s):

Alastair J. H. Brown ◽

Sophie J. Bradley ◽

Giles A. Brown ◽

Kirstie A. Bennett ◽

Jason Brown ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

Receptor Agonist ◽

Memory Loss ◽

Characterization of a Novel M1 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator Radioligand, [3H]PT-1284

Molecular Pharmacology ◽

10.1124/mol.116.104737 ◽

2016 ◽

Vol 90 (3) ◽

pp. 177-187 ◽

Cited By ~ 6

Author(s):

Deborah L. Smith ◽

Jennifer E. Davoren ◽

Jeremy R. Edgerton ◽

John T. Lazzaro ◽

Che-Wah Lee ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Allosteric Modulator ◽

Crosstalk between the M1 muscarinic acetylcholine receptor and the endocannabinoid system: A relevance for Alzheimer's disease?

Cellular Signalling ◽

10.1016/j.cellsig.2020.109545 ◽

2020 ◽

Vol 70 ◽

pp. 109545 ◽

Cited By ~ 1

Author(s):

Karen J. Thompson ◽

Andrew B. Tobin

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

Endocannabinoid System ◽

System A ◽

Surface modified nano-lipid drug conjugates of positive allosteric modulators of M1 muscarinic acetylcholine receptor for the treatment of Alzheimer’s disease

Medical Hypotheses ◽

10.1016/j.mehy.2017.01.026 ◽

2017 ◽

Vol 101 ◽

pp. 17-22 ◽

Cited By ~ 3

Author(s):

Pavan Kumar Chintamaneni ◽

Praveen T. Krishnamurthy ◽

Pachava Vengal Rao ◽

SaiKiran S.S. Pindiprolu

Keyword(s):

Alzheimer’S Disease ◽

Acetylcholine Receptor ◽

Allosteric Modulators ◽

Drug Conjugates ◽

Positive Allosteric Modulators ◽

M1 Muscarinic ◽

Surface Modified

5-HT2A receptor- and M1 muscarinic acetylcholine receptor-mediated Galpha(q) signalling in patients with psychiatric disorders

10.26226/morressier.5b68175eb56e9b005965c3a3 ◽

2018 ◽

Author(s):

Yuji Odagaki

Keyword(s):

Psychiatric Disorders ◽

Acetylcholine Receptor ◽