M1 muscarinic acetylcholine receptor in Alzheimer’s disease

P2-317: Suvn-i1312004, a novel M1 muscarinic acetylcholine receptor-positive allosteric modulator: Potential for the treatment of Alzheimer's disease

Alzheimer s & Dementia ◽

10.1016/j.jalz.2015.06.859 ◽

2015 ◽

Vol 11 (7S_Part_13) ◽

pp. P615-P616

Author(s):

Renny Abraham ◽

Ramkumar Subramanian ◽

Rajesh Babu Medapati ◽

Ravirala Venkateshwarlu ◽

Sumanth Yathavakilla ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

Allosteric Modulator ◽

Positive Allosteric Modulator ◽

P1-399: SUVN-I1307014: NOVEL M1 MUSCARINIC ACETYLCHOLINE RECEPTOR POSITIVE ALLOSTERIC MODULATOR FOR POTENTIAL TREATMENT OF ALZHEIMER'S DISEASE

Alzheimer s & Dementia ◽

10.1016/j.jalz.2014.05.641 ◽

2014 ◽

Vol 10 ◽

pp. P460-P460

Author(s):

Renny Abraham ◽

Medapati Rajesh Babu ◽

Rama Lakshmana ◽

Karthik Gadi ◽

Venkateshwarlu Ravirala ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

Allosteric Modulator ◽

Potential Treatment ◽

Positive Allosteric Modulator ◽

Allosteric modulation of the M1 muscarinic acetylcholine receptor: improving cognition and a potential treatment for schizophrenia and Alzheimer's disease

Drug Discovery Today ◽

10.1016/j.drudis.2013.09.005 ◽

2013 ◽

Vol 18 (23-24) ◽

pp. 1185-1199 ◽

Cited By ~ 78

Author(s):

Bruce J. Melancon ◽

James C. Tarr ◽

Joseph D. Panarese ◽

Michael R. Wood ◽

Craig W. Lindsley

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

Allosteric Modulation ◽

Potential Treatment ◽

From Structure to Clinic: Discovery of A M1 Muscarinic Acetylcholine Receptor Agonist for the Treatment of Memory Loss in Alzheimer's Disease

SSRN Electronic Journal ◽

10.2139/ssrn.3641933 ◽

2020 ◽

Author(s):

Alastair J. H. Brown ◽

Sophie J. Bradley ◽

Giles A. Brown ◽

Kirstie A. Bennett ◽

Jason Brown ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

Receptor Agonist ◽

Memory Loss ◽

Crosstalk between the M1 muscarinic acetylcholine receptor and the endocannabinoid system: A relevance for Alzheimer's disease?

Cellular Signalling ◽

10.1016/j.cellsig.2020.109545 ◽

2020 ◽

Vol 70 ◽

pp. 109545 ◽

Cited By ~ 1

Author(s):

Karen J. Thompson ◽

Andrew B. Tobin

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

Endocannabinoid System ◽

System A ◽

Surface modified nano-lipid drug conjugates of positive allosteric modulators of M1 muscarinic acetylcholine receptor for the treatment of Alzheimer’s disease

Medical Hypotheses ◽

10.1016/j.mehy.2017.01.026 ◽

2017 ◽

Vol 101 ◽

pp. 17-22 ◽

Cited By ~ 3

Author(s):

Pavan Kumar Chintamaneni ◽

Praveen T. Krishnamurthy ◽

Pachava Vengal Rao ◽

SaiKiran S.S. Pindiprolu

Keyword(s):

Alzheimer’S Disease ◽

Acetylcholine Receptor ◽

Allosteric Modulators ◽

Drug Conjugates ◽

Positive Allosteric Modulators ◽

M1 Muscarinic ◽

Surface Modified

5-HT2A receptor- and M1 muscarinic acetylcholine receptor-mediated Galpha(q) signalling in patients with psychiatric disorders

10.26226/morressier.5b68175eb56e9b005965c3a3 ◽

2018 ◽

Author(s):

Yuji Odagaki

Keyword(s):

Psychiatric Disorders ◽

Acetylcholine Receptor ◽

5-HT2A receptor- and M1 muscarinic acetylcholine receptor-mediated activation of Gαq/11 in postmortem dorsolateral prefrontal cortex of opiate addicts

Pharmacological Reports ◽

10.1007/s43440-021-00248-w ◽

2021 ◽

Author(s):

Yuji Odagaki ◽

Masakazu Kinoshita ◽

J. Javier Meana ◽

Luis F. Callado ◽

Jesús A. García-Sevilla

Keyword(s):

Prefrontal Cortex ◽

Acetylcholine Receptor ◽

Dorsolateral Prefrontal Cortex ◽

Dorsolateral Prefrontal ◽

Opiate Addicts ◽

Pharmacological Assessment of M1 Muscarinic Acetylcholine Receptor-Gq/11 Protein Coupling in Membranes Prepared from Postmortem Human Brain Tissue

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.108.137968 ◽

2008 ◽

Vol 325 (3) ◽

pp. 869-874 ◽

Cited By ~ 20

Author(s):

Hasib Salah-Uddin ◽

David R. Thomas ◽

Ceri H. Davies ◽

Jim J. Hagan ◽

Martyn D. Wood ◽

...

Keyword(s):

Human Brain ◽

Brain Tissue ◽

Acetylcholine Receptor ◽

Human Brain Tissue ◽

Postmortem Human Brain ◽

Protein Coupling ◽

Direct SUMOylation of M1 muscarinic acetylcholine receptor increases its ligand‐binding affinity and signal transduction

The FASEB Journal ◽

10.1096/fj.201800936r ◽

2018 ◽

Vol 33 (3) ◽

pp. 3237-3251 ◽

Cited By ~ 3

Author(s):

Jianrong Xu ◽

Panpan Tan ◽

Hui Li ◽

Yongyao Cui ◽

Yu Qiu ◽

...

Keyword(s):

Signal Transduction ◽

Ligand Binding ◽

Binding Affinity ◽

Acetylcholine Receptor ◽