P2-014: STRATEGIC MEMORY ALZHEIMERS REHABILITATION TRAINING (SMART) MEMORY PROGRAM FOR AMNESTIC MILD COGNITIVE IMPAIRMENT (AMCI): REPORTING THE RESULTS OF A RANDOMIZED CLINICAL TRIAL

2006 ◽  
Vol 14 (7S_Part_12) ◽  
pp. P670-P670
Author(s):  
John William DenBoer
Keyword(s):  
Clinical Trial ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Randomized Clinical Trial ◽  
Amnestic Mild Cognitive Impairment ◽  
Rehabilitation Training ◽  
Strategic Memory

Computerized Cognitive Training in Amnestic Mild Cognitive Impairment: A Randomized Clinical Trial

2021 ◽  
pp. 089198872110064
Author(s):  
Kevin Duff ◽  
Jian Ying ◽  
Kayla R. Suhrie ◽  
Bonnie C.A. Dalley ◽  
Taylor J. Atkinson ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Training ◽  
Computer Games ◽  
Brain Plasticity ◽  
Amnestic Mild Cognitive Impairment ◽  
Control Group ◽  
Computerized Cognitive Training ◽  
Secondary Outcomes

Objective: Computerized cognitive training has been successful in healthy older adults, but its efficacy has been mixed in patients with amnestic Mild Cognitive Impairment (MCI). Methods: In a randomized, placebo-controlled, double-blind, parallel clinical trial, we examined the short- and long-term efficacy of a brain-plasticity computerized cognitive training in 113 participants with amnestic MCI. Results: Immediately after 40-hours of training, participants in the active control group who played computer games performed better than those in the experimental group on the primary cognitive outcome (p = 0.02), which was an auditory memory/attention composite score. There were no group differences on 2 secondary outcomes (global cognitive composite and rating of daily functioning). After 1 year, there was no difference between the 2 groups on primary or secondary outcomes. No adverse events were noted. Conclusions: Although the experimental cognitive training program did not improve outcomes in those with MCI, the short-term effects of the control group should not be dismissed, which may alter treatment recommendations for these patients.

scholarly journals Keys to staying sharp: A randomized clinical trial of piano training among older adults with and without mild cognitive impairment

2019 ◽  
Vol 84 ◽  
pp. 105789 ◽  
Author(s):  
Elizabeth M. Hudak ◽  
Jennifer Bugos ◽  
Ross Andel ◽  
Jennifer J. Lister ◽  
Ming Ji ◽  
...  
Keyword(s):  
Older Adults ◽  
Clinical Trial ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Randomized Clinical Trial
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