Histologic Analysis of Acellular Dermal Matrix in the Treatment of Anal Fistula in an Animal Model

2009 ◽  
Vol 208 (6) ◽  
pp. 1099-1106 ◽  
Author(s):  
Jia Gang Han ◽  
Hui Min Xu ◽  
Wei Liang Song ◽  
Mu Lan Jin ◽  
Jia Sen Gao ◽  
...  
2013 ◽  
Vol 70 (4) ◽  
pp. 447-453 ◽  
Author(s):  
Richard S. Gaster ◽  
Aaron J. Berger ◽  
Stefanie D. Monica ◽  
Robert T. Sweeney ◽  
Ryan Endress ◽  
...  

Author(s):  
Javier Aragoneses ◽  
Ana Suárez ◽  
Cinthia Rodríguez ◽  
Juan Manuel Aragoneses

Acellular dermal matrix grafts (ADMG) have been used as soft tissue graft substitutes for autografts in periodontal plastic surgical procedures. They have benefits like avoiding a second surgical site and patient morbidity that have been associated with autografts, but there is limited evidence available on their tissue response and wound healing process. This histomorphometric animal model study was carried out in mini pigs and it aimed to compare the two types of ADMG materials of porcine derivative with a control group through observation of parameters like epithelial and Keratinized layer thickness, angiogenesis, cellularity, matrix resorption, and inflammatory infiltrate. The surgical technique involved punctures on the edentulous areas stripping the epithelial tissue and exposing the underlying connective tissue, placement of the ADMGs in the appropriate control and test sites. Following this, gingival biopsies were procured at three different time intervals of 15, 45, and 90 days. There were significant differences in epithelial and Keratinized layer thickness among the three groups. This study concluded that there was no clear consensus on which graft material was superior but it gave an insight into the tissue response and wound healing process associated with the graft materials.


2013 ◽  
Vol 22 (9) ◽  
pp. 1290-1297 ◽  
Author(s):  
Keiji Uezono ◽  
Junji Ide ◽  
Takuya Tokunaga ◽  
Hidetoshi Sakamoto ◽  
Nobukazu Okamoto ◽  
...  

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Aaron M. Kearney ◽  
Yufan Yan ◽  
Jonathan Bricker ◽  
Jennifer L. Pincus ◽  
Mohammed S. Alghoul

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Gianluca Franceschini ◽  
Riccardo Masetti

AbstractAcellular dermal matrices are biological materials of porcine, bovine, or human origin used as scaffold for reconstructive purpose in plastic surgery; these materials are well-tolerated and safely integrated in host tissues without causing resorption, contracture, and encapsulation thanks to their low antigenicity.Recently, human acellular dermal matrix has been used as a filler in breast-conserving surgery to improve aesthetic results. Adequate knowledge of biomaterials properties, appropriate skill, and careful compliance with some specific recommendations are mandatory in order to optimize outcomes and obtain a work of success.


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