Non-invasive Estimation of Pulmonary Hemodynamics from 2D-PC MRI with an Arterial Mechanics Method

Pulmonary hypertension (PH) in adults with congenital heart disease (CHD) and significant systemic-to-pulmonary shunting is a significant cause of morbidity and mortality. Its pathophysiology is incompletely understood, but involves a flow-induced pulmonary arteriopathy characterized by endothelial cell dysfunction and vascular remodeling that alters pulmonary arterial vasoreactivity. There is a paucity of literature linking PH with left-to-right shunting due to ruptured sinus of Valsalva aneurysms (SOVA). We present a unique case of reversible, flow-associated PH due to a ruptured congenital right SOVA fistulizing into the right atrium (RA), with emphasis on non-invasive and invasive assessment of pulmonary hemodynamics before and after surgical intervention.

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PULMONARY ARTERY ACCELERATION TIME, AN ACCURATE NON-INVASIVE MEASURE OF PULMONARY HEMODYNAMICS IN CHILDREN

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(15)61337-7 ◽

2015 ◽

Vol 65 (10) ◽

pp. A1337

Author(s):

Philip Thaler Levy ◽

Georgeann Groh ◽

Joshua Murphy ◽

Timothy Sekarski ◽

Mark Holland ◽

...

Keyword(s):

Pulmonary Artery ◽

Pulmonary Hemodynamics ◽

Acceleration Time ◽

Non Invasive

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IMAGING TECHNIQUES IN THE DIAGNOSIS OF PULMONARY HYPERTENSION

Wiadomości Lekarskie ◽

10.36740/wlek202009111 ◽

2020 ◽

Vol 73 (9) ◽

pp. 1867-1869

Author(s):

Weronika Topyła ◽

Michał Tomaszewski ◽

Agnieszka Wojtkowska ◽

Sylwia Łukasik ◽

Andrzej Wysokiński ◽

...

Keyword(s):

Pulmonary Hypertension ◽

Clinical Symptoms ◽

Imaging Techniques ◽

Diagnostic Algorithm ◽

Right Heart Catheterization ◽

Diagnostic Process ◽

Heart Catheterization ◽

Hypertension Detection ◽

Pulmonary Hemodynamics ◽

Non Invasive

Introduction: Pulmonary hypertension is defined as being a haemodynamic state, wherein the mean pulmonary artery pressure measured during right heart catheterization is equal or greater than 25 mmHg. As a result, right ventricular heart failure develops and clinical symptoms such as dyspnea, fatigue, weakness, angina and fainting occur. The aim: To highlight the role of imaging techniques in diagnostic process for pulmonary hypertension. Review and Disscusion: The diagnosis of pulmonary hypertension is multistage and often requires a number of studies. Currently, imaging techniques play a significant role in the diagnostic algorithm for pulmonary hypertension due to the fact that they are non-invasive and readily available, and many of their parameters are closely related to pulmonary hemodynamics. Conclusions: The diagnosis of pulmonary hypertension requires a multistep approach and a number of imaging studies. The suspicion of the disease is based on medical history, clinical symptoms and chest radiogram. Echocardiography plays a crucial role in pulmonary hypertension detection. A computed tomography and cardiac magnetic resonanceare valuable methods in determining the cause of suspected or confirmed pulmonary hypertension.

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CME Test for Echocardiographic Indexes for the Non-Invasive Evaluation of Pulmonary Hemodynamics

Journal of the American Society of Echocardiography ◽

10.1016/j.echo.2010.01.014 ◽

2010 ◽

Vol 23 (3) ◽

pp. 332-334

Keyword(s):

Pulmonary Hemodynamics ◽

Non Invasive ◽

Invasive Evaluation

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Echocardiographic Indexes for the Non-Invasive Evaluation of Pulmonary Hemodynamics

Journal of the American Society of Echocardiography ◽

10.1016/j.echo.2010.01.003 ◽

2010 ◽

Vol 23 (3) ◽

pp. 225-239 ◽

Cited By ~ 103

Author(s):

Alberto Milan ◽

Corrado Magnino ◽

Franco Veglio

Keyword(s):

Pulmonary Hemodynamics ◽

Non Invasive ◽

Invasive Evaluation

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X-ray microtomography

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100107058 ◽

1988 ◽

Vol 46 ◽

pp. 998-999

Author(s):

H.W. Deckman ◽

B.F. Flannery ◽

J.H. Dunsmuir ◽

K.D' Amico

Keyword(s):

Computed Tomography ◽

Internal Structure ◽

Imaging Technique ◽

Three Dimensional ◽

Tissue Structure ◽

Individual Element ◽

X Ray ◽

Non Invasive ◽

Panoramic Imaging ◽

Three Dimensional Images

We have developed a new X-ray microscope which produces complete three dimensional images of samples. The microscope operates by performing X-ray tomography with unprecedented resolution. Tomography is a non-invasive imaging technique that creates maps of the internal structure of samples from measurement of the attenuation of penetrating radiation. As conventionally practiced in medical Computed Tomography (CT), radiologists produce maps of bone and tissue structure in several planar sections that reveal features with 1mm resolution and 1% contrast. Microtomography extends the capability of CT in several ways. First, the resolution which approaches one micron, is one thousand times higher than that of the medical CT. Second, our approach acquires and analyses the data in a panoramic imaging format that directly produces three-dimensional maps in a series of contiguous stacked planes. Typical maps available today consist of three hundred planar sections each containing 512x512 pixels. Finally, and perhaps of most import scientifically, microtomography using a synchrotron X-ray source, allows us to generate maps of individual element.

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